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Fast procedures for the beam quality assessment and for the monitoring of beam energy modulations during the irradiation are among the most urgent improvements in particle therapy. Indeed, the online measurement of the particle beam energy…

This paper focuses on some dosimetry aspects of proton therapy and pencil beam scanning based on the experience accumulated at Paul Scherrer Institute(PSI). The basic formalism for absolute dosimetry in proton therapy is outlined and the…

Medical Physics · Physics 2018-04-24 S. Safai

Purpose: Anthropomorphic phantoms can be used in radiotherapy to confirm dose distributions. In this work, a prototype phantom with a deformable chest wall was created based on real human. Methods: A technique similar to 3-dimensional…

Medical Physics · Physics 2021-11-11 Maria Akiki , Fadi Rouphael , Mazen Moussallem

How to evaluate and compare image quality from different sub-micrometer (sub$\mu$) CT scans? A simple test phantom made of polymer microbeads is used for recording projection images as well as 13 CT scans in a number of commercial and…

The purpose of this work is to provide a fast and accurate scatter artifacts correction algorithm for cone beam CT (CBCT) imaging. The method starts with an estimation of coarse scatter profiles for a set of CBCT data in either image domain…

Medical Physics · Physics 2016-04-27 Wei Zhao , Don Vernekohl , Jun Zhu , Luyao Wang , Lei Xing

Purpose: Cone-beam CT (CBCT) plays an important role in image guided radiation therapy (IGRT). However, the large radiation dose from serial CBCT scans in most IGRT procedures raises a clinical concern, especially for pediatric patients who…

Medical Physics · Physics 2015-05-18 Xun Jia , Yifei Lou , Ruijiang Li , William Y. Song , Steve B. Jiang

Enhanced-accuracy ion-range verification in real time shall enable a significant step forward in the use of therapeutic ion beams. Positron-emission tomography (PET) and prompt-gamma imaging (PGI) are two of the most promising and…

Background: Treatment verification with PET imaging in charged particle therapy is conventionally done by comparing measurements of spatial distributions with Monte Carlo (MC) predictions. However, decay curves can provide additional…

Purpose: Dual-energy CT (DECT) has been shown to derive stopping power ratio (SPR) map with higher accuracy than conventional single energy CT (SECT) by obtaining the energy dependence of photon interactions. However, DECT is not as widely…

Purpose: To apply a convolutional neural network (CNN) to develop a system that segments intensity calibration phantom regions in computed tomography (CT) images, and to test the system in a large cohort to evaluate its robustness. Methods:…

Computer Vision and Pattern Recognition · Computer Science 2020-12-22 Keisuke Uemura , Yoshito Otake , Masaki Takao , Mazen Soufi , Akihiro Kawasaki , Nobuhiko Sugano , Yoshinobu Sato

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

Proton radiography is a new scatheless diagnostic tool, and which provides a potential development direction for advanced hydrotesting. Recently a low energy proton radiography system has been developed at CAEP. This system has been…

Accelerator Physics · Physics 2013-10-22 Tao Wei , Guojun Yang , Jidong Long , Xiaozhong He , Yiding Li , Xiaoding Zhang , Chaofan Ma , Liangchao Zhao , Jinshui Shi

Purpose: Cone-beam CT (CBCT) projection images provide anatomical data in real-time over several respiratory cycles, forming a comprehensive picture of tumor movement. We developed and validated a method which uses these projections to…

Medical Physics · Physics 2015-01-15 Bernard L. Jones , David Westerly , Moyed Miften

A novel dose calculation approach was designed based on the application of LSTM network that processes the 3D patient/phantom geometry as a sequence of 2D computed tomography input slices yielding a corresponding sequence of 2D slices that…

Medical Physics · Physics 2021-06-09 Ahmad Neishabouri , Niklas Wahl , Ulrich Köthe , Mark Bangert

The foreseen CaLIPSO Positron Emission Tomography (PET) scanner is expected to yield simultaneously a fine image resolution, about 1 mm$^3$, and a high contrast. In this paper we present results of simulations for the full CaLIPSO PET…

Single-bed whole-body positron emission tomography based on resistive plate chamber detectors (RPC-PET) has been proposed for human studies, as a complementary resource to scintillator-based PET scanners. The purpose of this work is mainly…

Computed tomography (CT) scans are a major source of medical radiation exposure worldwide. In countries like China, the frequency of CT scans has grown rapidly, particularly in routine physical examinations where chest CT scans are…

Medical Physics · Physics 2025-04-10 Zirui Ye , Bei Yao , Haoran Zheng , Li Tao , Ripeng Wang , Yankui Chang , Zhi Chen , Yingming Zhao , Wei Wei , Xie George Xu

Proton radiography is used for advanced hydrotesting as a new type radiography technology due to its powerful penetration capability and high detection efficiency. A new proton radiography terminal will be developed to radiograph static…

Accelerator Physics · Physics 2015-01-28 Yan Yan , Li-Na Sheng , Zhi-Wu Huang , Jie Wang , Ze-En Yao , Jun-Run Wang , Zheng Wei , Jian-Cheng Yang , You-Jin Yuan

Cone-beam CT (CBCT) is installed in the treatment room to facilitate online clinical applications, including image guidance in radiation and surgery. Half-fan and short-can are the commonly used modes in clinical applications to expand the…

Medical Physics · Physics 2022-05-24 Junbo Peng

Our aim was to enhance visual quality and quantitative accuracy of dynamic positron emission tomography (PET)uptake images by improved image reconstruction, using sophisticated sparse penalty models that incorporate both 2D spatial+1D…

Computer Vision and Pattern Recognition · Computer Science 2019-06-17 Ida Häggström , Yizun Lin , Si Li , Andrzej Krol , Yuesheng Xu , C. Ross Schmidtlein
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