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Deep Convolutional Neural Networks have become a Swiss knife in solving critical artificial intelligence tasks. However, deploying deep CNN models for latency-critical tasks remains to be challenging because of the complex nature of CNNs.…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Chuanhao Zhuge , Xinheng Liu , Xiaofan Zhang , Sudeep Gummadi , Jinjun Xiong , Deming Chen

Genome sequence analysis has enabled significant advancements in medical and scientific areas such as personalized medicine, outbreak tracing, and the understanding of evolution. Unfortunately, it is currently bottlenecked by the…

In-time particle trajectory reconstruction in the Large Hadron Collider is challenging due to the high collision rate and numerous particle hits. Using GNN (Graph Neural Network) on FPGA has enabled superior accuracy with flexible…

Hardware Architecture · Computer Science 2023-06-28 Shi-Yu Huang , Yun-Chen Yang , Yu-Ru Su , Bo-Cheng Lai , Javier Duarte , Scott Hauck , Shih-Chieh Hsu , Jin-Xuan Hu , Mark S. Neubauer

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex…

Other Quantitative Biology · Quantitative Biology 2014-03-12 Jian-Jun Shu , Li Shan Ouw

The advent of Generative Adversarial Networks (GANs) has brought about completely novel ways of transforming and manipulating pixels in digital images. GAN based techniques such as Image-to-Image translations, DeepFakes, and other automated…

Computer Vision and Pattern Recognition · Computer Science 2019-10-04 Lakshmanan Nataraj , Tajuddin Manhar Mohammed , Shivkumar Chandrasekaran , Arjuna Flenner , Jawadul H. Bappy , Amit K. Roy-Chowdhury , B. S. Manjunath

Approximate nearest neighbor search (ANNS) in high-dimensional vector spaces has a wide range of real-world applications. Numerous methods have been proposed to handle ANNS efficiently, while graph-based indexes have gained prominence due…

Databases · Computer Science 2025-08-14 Zhonggen Li , Xiangyu Ke , Yifan Zhu , Bocheng Yu , Baihua Zheng , Yunjun Gao

DNA computing is an unconventional approach to computing that harnesses the parallelism and information storage capabilities of DNA molecules. It has emerged as a promising field with potential applications in solving a variety of…

Emerging Technologies · Computer Science 2024-06-04 Muhammad Asad Tariq , Rafay Junaid , Muhammad Mehdy Hasnain , Danyal Farhat

One of the most popular tools for large scale gene expression studies are high-density oligonucleotide (GeneChip(R)) arrays. These currently have 16-20 small probe cells (``features'') for evaluating the transcript abundance of each gene.…

Biological Physics · Physics 2007-05-23 Felix Naef , Daniel A. Lim , Nila Patil , Marcelo O. Magnasco

Graph Neural Networks (GNNs) have shown great superiority on non-Euclidean graph data, achieving ground-breaking performance on various graph-related tasks. As a practical solution to train GNN on large graphs with billions of nodes and…

Machine Learning · Computer Science 2024-09-24 Zeyu Zhu , Peisong Wang , Qinghao Hu , Gang Li , Xiaoyao Liang , Jian Cheng

Powerful yet complex deep neural networks (DNNs) have fueled a booming demand for efficient DNN solutions to bring DNN-powered intelligence into numerous applications. Jointly optimizing the networks and their accelerators are promising in…

Machine Learning · Computer Science 2025-01-07 Yongan Zhang , Yonggan Fu , Weiwen Jiang , Chaojian Li , Haoran You , Meng Li , Vikas Chandra , Yingyan Celine Lin

Pedigree GWAS (Option 29) in the current version of the Mendel software is an optimized subroutine for performing large scale genome-wide QTL analysis. This analysis (a) works for random sample data, pedigree data, or a mix of both, (b) is…

Applications · Statistics 2014-08-01 Hua Zhou , Jin Zhou , Tao Hu , Eric M Sobel , Kenneth Lange

We improve on GenASM, a recent algorithm for genomic sequence alignment, by significantly reducing its memory footprint and bandwidth requirement. Our algorithmic improvements reduce the memory footprint by 24$\times$ and the number of…

Hardware Architecture · Computer Science 2022-03-30 Joël Lindegger , Damla Senol Cali , Mohammed Alser , Juan Gómez-Luna , Onur Mutlu

Most of the existing work on FPGA acceleration of Convolutional Neural Network (CNN) focus on employing a single strategy (algorithm, dataflow, etc.) across all the layers. Such an approach does not achieve optimal latency on complex and…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-03-16 Yuan Meng , Sanmukh Kuppannagari , Rajgopal Kannan , Viktor Prasanna

Loopy Belief Propagation (LBP) is a widely used approximate inference algorithm in probabilistic graphical models, with applications in computer vision, error correction codes, protein folding, program analysis, etc. However, LBP faces…

Software Engineering · Computer Science 2025-09-29 Haoyu Feng , Xin Zhang

Subgraph matching has garnered increasing attention for its diverse real-world applications. Given the dynamic nature of real-world graphs, addressing evolving scenarios without incurring prohibitive overheads has been a focus of research.…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-31 Linshan Qiu , Lu Chen , Hailiang Jie , Xiangyu Ke , Yunjun Gao , Yang Liu , Zetao Zhang

Motif discovery in DNA sequences is a challenging task in molecular biology. In computational motif discovery, Planted (l, d) motif finding is a widely studied problem and numerous algorithms are available to solve it. Both hardware and…

Computational Engineering, Finance, and Science · Computer Science 2014-03-07 P. Perera , R. G. Ragel

Implementing Deep Neural Networks (DNNs) on resource-constrained edge devices is a challenging task that requires tailored hardware accelerator architectures and a clear understanding of their performance characteristics when executing the…

The ability to detect fragments of deleted image files and to reconstruct these image files from all available fragments on disk is a key activity in the field of digital forensics. Although reconstruction of image files from the file…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-01-12 Sylvain Collange , Yoginder Dandass , Marc Daumas , David Defour

We propose a novel couple mappings method for low resolution face recognition using deep convolutional neural networks (DCNNs). The proposed architecture consists of two branches of DCNNs to map the high and low resolution face images into…

Computer Vision and Pattern Recognition · Computer Science 2017-06-21 Erfan Zangeneh , Mohammad Rahmati , Yalda Mohsenzadeh

Genomic signal processing has been used successfully in bioinformatics to analyze biomolecular sequences and gain varied insights into DNA structure, gene organization, protein binding, sequence evolution, etc. But challenges remain in…

Genomics · Quantitative Biology 2022-11-04 Saish Jaiswal , Shreya Nema , Hema A Murthy , Manikandan Narayanan
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