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Biology has taken strong steps towards becoming a computer science aiming at reprogramming nature after the realisation that nature herself has reprogrammed organisms by harnessing the power of natural selection and the digital prescriptive…

Neural and Evolutionary Computing · Computer Science 2016-01-21 Hector Zenil , Angelika Schmidt , Jesper Tegnér

In this paper the author presents some non-conventional thoughts on the complexity of the Universe and the algorithmic reproducibility of the human brain, essentially sparked off by the notion of algorithmic complexity. We must warn that…

History and Overview · Mathematics 2007-05-23 Germano D'Abramo

Understanding large molecular networks consisting of entities such as genes, proteins or RNAs that interact in complex ways to drive the cellular machinery has been an active focus of systems biology. Computational approaches have played a…

Molecular Networks · Quantitative Biology 2013-04-23 Sriganesh Srihari , Mark A. Ragan

Computational problems can be classified according to their algorithmic complexity, which is defined based on how the resources needed to solve the problem, e.g. the execution time, scale with the problem size. Many problems in…

Computational Complexity · Computer Science 2021-07-29 Davide Cirillo , Miguel Ponce-de-Leon , Alfonso Valencia

At the intersection of what I call uncomputable art and computational epistemology, a form of experimental philosophy, we find an exciting and promising area of science related to causation with an alternative, possibly best possible,…

Other Computer Science · Computer Science 2021-09-20 Hector Zenil

An astonishingly diverse biomolecular circuitry orchestrates the functioning machinery underlying every living cell. These biomolecules and their circuits have been engineered not only for various industrial applications but also to perform…

Biomolecules · Quantitative Biology 2021-02-15 Sahana Gangadharan , Karthik Raman

A coherent mathematical overview of computation and its generalisations is described. This conceptual framework is sufficient to comfortably host a wide range of contemporary thinking on embodied computation and its models.

Logic in Computer Science · Computer Science 2013-03-12 S. Barry Cooper

Scientists have demonstrated that quantum computing has presented novel approaches to address computational challenges, each varying in complexity. Adapting problem-solving strategies is crucial to harness the full potential of quantum…

Computational Complexity · Computer Science 2024-09-13 Arash Vaezi , Ali Movaghar , Mohammad Ghodsi , Seyed Mohammad Hussein Kazemi , Negin Bagheri Noghrehy , Seyed Mohsen Kazemi

I am most honoured to have the privilege to present the Foreword to this fascinating and wonderfully varied collection of contributions, concerning the nature of computation and of its deep connection with the operation of those basic laws,…

General Literature · Computer Science 2012-05-29 Roger Penrose

One might think that, once we know something is computable, how efficiently it can be computed is a practical question with little further philosophical importance. In this essay, I offer a detailed case that one would be wrong. In…

Computational Complexity · Computer Science 2024-05-11 Scott Aaronson

Causality is a fundamental part of the scientific endeavour to understand the world. Unfortunately, causality is still taboo in much of psychology and social science. Motivated by a growing number of recommendations for the importance of…

Methodology · Statistics 2022-06-27 Matthew J. Vowels

Here we address the challenge of profiling causal properties and tracking the transformation of chemical compounds from an algorithmic perspective. We explore the potential of applying a computational interventional calculus based on the…

Molecular Networks · Quantitative Biology 2018-03-20 Hector Zenil , Narsis A. Kiani , Ming-Mei Shang , Jesper Tegnér

Machine Learning explainability techniques have been proposed as a means of `explaining' or interrogating a model in order to understand why a particular decision or prediction has been made. Such an ability is especially important at a…

Machine Learning · Statistics 2022-02-28 Matthew J. Vowels

We introduce computational causal inference as an interdisciplinary field across causal inference, algorithms design and numerical computing. The field aims to develop software specializing in causal inference that can analyze massive…

Computation · Statistics 2020-07-22 Jeffrey C. Wong

In this paper, we analyze axiomatic issues of unconventional computations from a methodological and philosophical point of view. We explain how the new models of algorithms changed the algorithmic universe, making it open and allowing…

General Literature · Computer Science 2012-07-05 Gordana Dodig-Crnkovic , Mark Burgin

Causality has become a fundamental approach for explaining the relationships between events, phenomena, and outcomes in various fields of study. It has invaded various fields and applications, such as medicine, healthcare, economics,…

Artificial Intelligence · Computer Science 2024-03-19 Abraham Itzhak Weinberg , Cristiano Premebida , Diego Resende Faria

One approach to confronting computational hardness is to try to understand the contribution of various parameters to the running time of algorithms and the complexity of computational tasks. Almost no computational tasks in real life are…

Computational Complexity · Computer Science 2011-11-23 Rodney G. Downey , Dimitrios M. Thilikos

Over the past two decades, the rapid surge in data-intensive computational techniques for statistical modeling may have had the effect of diminishing the use of applied mathematics in causal scientific inquiry. In this paper, co-authored by…

History and Philosophy of Physics · Physics 2026-05-13 Marzieh Asgari-Targhi , Amene Asgari-Targhi , Mahboubeh Asgari-Targhi , Edward J. , Hall

Deep Learning models have shown success in a large variety of tasks by extracting correlation patterns from high-dimensional data but still struggle when generalizing out of their initial distribution. As causal engines aim to learn…

Machine Learning · Computer Science 2024-01-02 Gaël Gendron , Michael Witbrock , Gillian Dobbie

The search for meaningful structure in biological data has relied on cutting-edge advances in computational technology and data science methods. However, challenges arise as we push the limits of scale and complexity in biological problems.…

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