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Correlation is not causation. As simple as this widely agreed-upon statement may seem, scientifically defining causality and using it to drive our modern biomedical research is immensely challenging. In this perspective, we attempt to…

Molecular Networks · Quantitative Biology 2024-01-19 Sebastian Lobentanzer , Pablo Rodriguez-Mier , Stefan Bauer , Julio Saez-Rodriguez

Computational complexity is a core theory of computer science, which dictates the degree of difficulty of computation. There are many problems with high complexity that we have to deal, which is especially true for AI. This raises a big…

Computational Complexity · Computer Science 2023-01-10 Chuyu Xiong

In this paper we analyze methodological and philosophical implications of algorithmic aspects of unconventional computation. At first, we describe how the classical algorithmic universe developed and analyze why it became closed in the…

Other Computer Science · Computer Science 2012-11-20 Mark Burgin , Gordana Dodig-Crnkovic

We discuss the computational complexity and feasibility properties of scenario based techniques for uncertain optimization programs. We consider different solution alternatives ranging from the standard scenario approach to recursive…

Optimization and Control · Mathematics 2014-12-16 Nikolaos Kariotoglou , Kostas Margellos , John Lygeros

We discuss various universality aspects of numerical computations using standard algorithms. These aspects include empirical observations and rigorous results. We also make various speculations about computation in a broader sense.

Probability · Mathematics 2017-03-24 Percy Deift , Thomas Trogdon

Computational scientists are facing a new era where the old ways of developing and reusing code have to be left behind and a few daring steps are to be made towards new horizons. The present work analyzes the needs that drive this change,…

Computational Engineering, Finance, and Science · Computer Science 2021-08-23 Zsolt I. Lázár , Jouke R. Heringa , Bazil Pârv , Simon W. de Leeuw

Causal reasoning is essential to science, yet quantum theory challenges it. Quantum correlations violating Bell inequalities defy satisfactory causal explanations within the framework of classical causal models. What is more, a theory…

Quantum Physics · Physics 2021-03-05 Jonathan Barrett , Robin Lorenz , Ognyan Oreshkov

Probabilities of causation provide principled ways to assess causal relationships but face computational challenges due to partial identifiability and latent confounding. This paper introduces both algorithmic simplifications, significantly…

How can complexity theory and algorithms benefit from practical advances in computing? We give a short overview of some prior work using practical computing to attack problems in computational complexity and algorithms, informally describe…

Computational Complexity · Computer Science 2008-11-11 Ryan Williams

This article summarises a Web-book on "Complexity" that was developed to introduce undergraduate students to interesting complex systems in the biological, physical and social sciences, and the common tools, principles and concepts used for…

Physics Education · Physics 2007-05-23 Rajesh R. Parwani

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

Neurons and Cognition · Quantitative Biology 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

Computation models such as circuits describe sequences of computation steps that are carried out one after the other. In other words, algorithm design is traditionally subject to the restriction imposed by a fixed causal order. We address a…

Quantum Physics · Physics 2017-07-04 Ämin Baumeler , Stefan Wolf

Complex processes often arise from sequences of simpler interactions involving a few particles at a time. These interactions, however, may not be directly accessible to experiments. Here we develop the first efficient method for unravelling…

Quantum Physics · Physics 2022-06-24 Ge Bai , Ya-Dong Wu , Yan Zhu , Masahito Hayashi , Giulio Chiribella

We deliver a call to arms for probabilistic numerical methods: algorithms for numerical tasks, including linear algebra, integration, optimization and solving differential equations, that return uncertainties in their calculations. Such…

Numerical Analysis · Mathematics 2016-02-17 Philipp Hennig , Michael A Osborne , Mark Girolami

Causality has gained popularity in recent years. It has helped improve the performance, reliability, and interpretability of machine learning models. However, recent literature on explainable artificial intelligence (XAI) has faced…

Artificial Intelligence · Computer Science 2025-07-11 Samuel Reyd , Ada Diaconescu , Jean-Louis Dessalles

Many proposed applications of neural networks in machine learning, cognitive/brain science, and society hinge on the feasibility of inner interpretability via circuit discovery. This calls for empirical and theoretical explorations of…

Artificial Intelligence · Computer Science 2025-04-02 Federico Adolfi , Martina G. Vilas , Todd Wareham

Linear Programs (LP) are celebrated widely, particularly so in machine learning where they have allowed for effectively solving probabilistic inference tasks or imposing structure on end-to-end learning systems. Their potential might seem…

Artificial Intelligence · Computer Science 2022-03-30 Matej Zečević , Florian Peter Busch , Devendra Singh Dhami , Kristian Kersting

This short course offers a new perspective on randomized algorithms for matrix computations. It explores the distinct ways in which probability can be used to design algorithms for numerical linear algebra. Each design template is…

Numerical Analysis · Mathematics 2025-09-23 Anastasia Kireeva , Joel A. Tropp

Researchers in the field of biocomputing have, for many years, successfully "harvested and exploited" the natural world for inspiration in developing systems that are robust, adaptable and capable of generating novel and even "creative"…

Artificial Intelligence · Computer Science 2007-05-23 Jon Timmis , Martyn Amos , Wolfgang Banzhaf , Andy Tyrrell

Causal discovery studies the problem of mining causal relationships between variables from data, which is of primary interest in science. During the past decades, significant amount of progresses have been made toward this fundamental data…

Artificial Intelligence · Computer Science 2016-11-28 Kui Yu , Jiuyong Li , Lin Liu