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We consider within-host virus models with more than one strain and allow mutation between the strains. If there is no mutation, a Lyapunov function establishes global stability of the steady state corresponding to the fittest strain. For…

Cell Behavior · Quantitative Biology 2007-08-01 Patrick De Leenheer , Sergei S. Pilyugin

We introduce a nonlinear structured population model with diffusion in the state space. Individuals are structured with respect to a continuous variable which represents a pathogen load. The class of uninfected individuals constitutes a…

Analysis of PDEs · Mathematics 2019-03-25 Angel Calsina , Jozsef Z. Farkas

We study the early stages of viral infection, and the distribution of times to obtain a persistent infection. The virus population proliferates by entering and reproducing inside a target cell until a sufficient number of new virus…

Populations and Evolution · Quantitative Biology 2019-07-11 Carmel Sagi , Michael Assaf

This paper addresses the stability problem for discrete-time switched systems under autonomous switching. Each mode of the switched system is modeled as a Linear Parameter Varying (LPV) system, the time-varying parameters can vary…

Systems and Control · Electrical Eng. & Systems 2020-05-13 Márcio J. Lacerda , Cristiano M. Agulhari

We study a dynamic infection spread model, inspired by the discrete time SIR model, where infections are spread via non-isolated infected individuals. While infection keeps spreading over time, a limited capacity testing is performed at…

Methodology · Statistics 2022-01-25 Batuhan Arasli , Sennur Ulukus

Partial differential equation (PDE) models for infectious disease have received renewed interest in recent years. Most models of this type extend classical compartmental formulations with additional terms accounting for spatial dynamics,…

Populations and Evolution · Quantitative Biology 2025-04-29 Pierluigi Colli , Gabriela Marinoschi , Elisabetta Rocca , Alex Viguerie

In this paper, we investigate a class of non-monotone reaction-diffusion equations with distributed delay and a homogenous boundary Neumann condition, which have a positive steady state. The main concern is the global attractivity of the…

Dynamical Systems · Mathematics 2018-10-03 Tarik Mohammed Touaoula

New estimates and global existence results are provided for a class of systems of cross diffusion equations arising from the modeling of chemotaxis with local sensing, possibly featuring a growth term of logistic-type as well. For sublinear…

Analysis of PDEs · Mathematics 2022-02-22 Laurent Desvillettes , Philippe Laurençot , Ariane Trescases , Michael Winkler

We consider a time-inhomogeneous diffusion process able to describe the dynamics of infected people in a susceptible-infectious epidemic model in which the transmission intensity function is time-dependent. Such a model is well suited to…

Methodology · Statistics 2024-10-30 Giuseppina Albano , Virginia Giorno , Francisco Torres-Ruiz

Reaction diffusion systems are often used to study pattern formation in biological systems. However, most methods for understanding their behavior are challenging and can rarely be applied to complex systems common in biological…

Analysis of PDEs · Mathematics 2013-05-24 William R. Holmes

This paper conducts research on the established model and presents the main conclusions . Firstly, by separately considering the infectivity of each of the two infectious diseases and the infectivity of the population simultaneously…

Populations and Evolution · Quantitative Biology 2025-03-13 Yang Liu

This thesis addresses the question of stability of systems defined by differential equations which contain nonlinearity and delay. In particular, we analyze the stability of a well-known delayed nonlinear implementation of a certain…

Dynamical Systems · Mathematics 2007-05-23 Matthew M. Peet

The movement of organisms and cells can be governed by occasional long distance runs, according to an approximate L\'evy walk. For T cells migrating through chronically-infected brain tissue, runs are further interrupted by long pauses, and…

Biological Physics · Physics 2020-03-06 Gissell Estrada-Rodriguez , Heiko Gimperlein , Kevin J. Painter , Jakub Stocek

We consider nonautonomous cyclic systems of delay differential equations with variable delay. Under suitable feedback assumptions, we define an (integer valued) Lyapunov functional related to the number of sign changes of the coordinate…

Dynamical Systems · Mathematics 2025-10-10 István Balázs , Ábel Garab

Two important classes of spatio-temporal patterns, namely, spatio-temporal chaos and self-replicating patterns, for a representative three variable autocatalytic reaction mechanism coupled with diffusion has been studied. The…

chao-dyn · Physics 2015-06-24 Nita Parekh , V. Ravi Kumar , B. D. Kulkarni

In this article a space-dependent epidemic model equipped with a constant latency period is examined. We construct a delay partial integro-differential equation and show that its solution possesses some biologically reasonable features. We…

Numerical Analysis · Mathematics 2022-08-02 B. Takács , I. Faragó , R. Horváth , D. Repovš

This paper is devoted to the investigation of the nonnegative solutions and the stability and asymptotic properties of the solutions of fractional differential dynamic systems involving delayed dynamics with point delays. The obtained…

Dynamical Systems · Mathematics 2010-09-23 Manuel De la Sen

The paper is devoted to the study of stability of equilibrium solutions of a delay differential equation that models leukemia. The equation was previously studied in [5] and [6], where the emphasis is put on the numerical study of periodic…

Dynamical Systems · Mathematics 2010-01-27 Anca Veronica Ion

The present paper is devoted to the investigation of the long time dynamics for a double free boundary system with nonlocal diffusions, which models the infectious diseases transmitted via digestive system such as fecal-oral diseases,…

Dynamical Systems · Mathematics 2021-06-10 Thanh-Hieu Nguyen , Hoang-Hung Vo

This study presents an improved mathematical model for Hepatitis B Virus (HBV) transmission dynamics by investigating autonomous and nonautonomous cases. The novel model incorporates the effects of medical treatment, allowing for a more…

Dynamical Systems · Mathematics 2025-05-15 Abdallah Alsammani