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A key element of the European Union's Human Brain Project (HBP) and other large-scale brain research projects is simulation of large-scale model networks of neurons. Here we argue why such simulations will likely be indispensable for…

The network architecture of the human brain has become a feature of increasing interest to the neuroscientific community, largely because of its potential to illuminate human cognition, its variation over development and aging, and its…

Neurons and Cognition · Quantitative Biology 2016-11-07 Richard F. Betzel , Danielle S. Bassett

Human learning is a complex phenomenon that requires adaptive processes across a range of temporal and spacial scales. While our understanding of those processes at single scales has increased exponentially over the last few years, a…

Neurons and Cognition · Quantitative Biology 2016-09-08 Marcelo G. Mattar , Danielle S. Bassett

The underlying physiological mechanisms of generating conscious states are still unknown. To make progress on the problem of consciousness, we will need to experimentally design a system that evolves in a similar way our brains do. Recent…

Emerging Technologies · Computer Science 2014-11-20 Dorian Aur

In recent years, neuroscience has made significant progress in building large-scale artificial neural network (ANN) models of brain activity and behavior. However, there is no consensus on the most efficient ways to collect data and design…

Optical imaging of the brain has expanded dramatically in the past two decades. New optics, indicators, and experimental paradigms are now enabling in-vivo imaging from the synaptic to the cortex-wide scales. To match the resulting flood of…

Image and Video Processing · Electrical Eng. & Systems 2024-02-15 Gal Mishne , Adam Charles

Computational psychiatry is a field aimed at developing formal models of information processing in the human brain, and how alterations in this processing can lead to clinical phenomena. Despite significant progress in the development of…

Neurons and Cognition · Quantitative Biology 2023-01-12 David Benrimoh , Victoria Fisher , Catalina Mourgues , Andrew D. Sheldon , Ryan Smith , Albert R. Powers

To understand Working of Human Brain measurements related to the brain function are required. These measurements should be possibly non-invasive. Brain should be disturbed as less as possible during the measurement. Integration of various…

Emerging Technologies · Computer Science 2015-06-16 Revati Shriram , M. Sundhararajan , Nivedita Daimiwal

The brain is a highly complex organ consisting of a myriad of subsystems that flexibly interact and adapt over time and context to enable perception, cognition, and behavior. Understanding the multi-scale nature of the brain, i.e., how…

Neurons and Cognition · Quantitative Biology 2025-01-17 Adam S. Charles

Building machines that learn and think like humans is essential not only for cognitive science, but also for computational neuroscience, whose ultimate goal is to understand how cognition is implemented in biological brains. A new cognitive…

Artificial Intelligence · Computer Science 2017-11-15 Nikolaus Kriegeskorte , Robert M. Mok

The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers and synapses. For…

Brain signal data are inherently big: massive in amount, complex in structure, and high in dimensions. These characteristics impose great challenges for statistical inference and learning. Here we review several key challenges, discuss…

Methodology · Statistics 2017-11-02 Zhaoxia Yu , Dustin Pluta , Tong Shen , Chuansheng Chen , Gui Xue , Hernando Ombao

The brain is a powerful tool used to achieve amazing feats. There have been several significant advances in neuroscience and artificial brain research in the past two decades. This article is a review of such advances, ranging from the…

Artificial Intelligence · Computer Science 2016-05-16 Gabriel Makdah

Cognitive neuroscience is enjoying rapid increase in extensive public brain-imaging datasets. It opens the door to large-scale statistical models. Finding a unified perspective for all available data calls for scalable and automated…

Machine Learning · Statistics 2019-05-16 Arthur Mensch , Julien Mairal , Danilo Bzdok , Bertrand Thirion , Gaël Varoquaux

One of the current AI issues depicted in popular culture is the fear of conscious super AIs that try to take control over humanity. And as computational power goes upwards and that turns more and more into a reality, understanding…

Neurons and Cognition · Quantitative Biology 2023-05-22 Daniel Lopes

The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…

Neurons and Cognition · Quantitative Biology 2024-08-06 Suman Kulkarni , Dani S. Bassett

Neuroimaging has profoundly enhanced our understanding of the human brain by characterizing its structure, function, and connectivity through modalities like MRI, fMRI, EEG, and PET. These technologies have enabled major breakthroughs…

Applications · Statistics 2026-02-16 Jian Kang , Thomas Nichols , Lexin Li , Martin A. Lindquist , Hongtu Zhu

For constructing neuronal network models computational neuroscientists have access to wide-ranging anatomical data that nevertheless tend to cover only a fraction of the parameters to be determined. Finding and interpreting the most…

To learn how cognition is implemented in the brain, we must build computational models that can perform cognitive tasks, and test such models with brain and behavioral experiments. Cognitive science has developed computational models of…

Neurons and Cognition · Quantitative Biology 2018-08-01 Nikolaus Kriegeskorte , Pamela K. Douglas
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