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In this work, we present the first corpus for German Adverse Drug Reaction (ADR) detection in patient-generated content. The data consists of 4,169 binary annotated documents from a German patient forum, where users talk about health issues…

Computation and Language · Computer Science 2022-08-04 Lisa Raithel , Philippe Thomas , Roland Roller , Oliver Sapina , Sebastian Möller , Pierre Zweigenbaum

Adverse drug reaction (ADR) is widely concerned for public health issue. In this study we propose an original approach to detect the ADRs using feature matrix and feature selection. The experiments are carried out on the drug Simvastatin.…

Computational Engineering, Finance, and Science · Computer Science 2013-07-05 Yihui Liu , Uwe Aickelin

Social media can be an important source of information facilitating the detection of new safety signals in pharmacovigilance. Various approaches have investigated the analysis of social media data using AI such as NLP techniques for…

Computation and Language · Computer Science 2022-03-08 Valentin Roche , Jean-Philippe Robert , Hanan Salam

Adverse Drug Reactions (ADRs) from psychiatric medications are the leading cause of hospitalizations among mental health patients. With healthcare systems and online communities facing limitations in resolving ADR-related issues, Large…

Adverse drug reactions (ADRs) are a major barrier to safe and effective pharmacotherapy and increasingly reflect higher order interactions between drugs, genetic background, and clinical phenotypes. Existing graph based approaches usually…

Quantitative Methods · Quantitative Biology 2025-12-02 Ze Cai , Haotian Tang , Shuai Gao , Binbin Zhou , Junhan Zhao , Jun Wen

Cyber incidents can have a wide range of cause from a simple connection loss to an insistent attack. Once a potential cyber security incidents and system failures have been identified, deciding how to proceed is often complex. Especially,…

Computers and Society · Computer Science 2020-07-16 Sandro Passarelli , Cem Gündogan , Lars Stiemert , Matthias Schopp , Peter Hillmann

Automatic monitoring of adverse drug events (ADEs) or reactions (ADRs) is currently receiving significant attention from the biomedical community. In recent years, user-generated data on social media has become a valuable resource for this…

Computation and Language · Computer Science 2023-11-21 Ilseyar Alimova , Elena Tutubalina

Social media is an useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance. We study the problem of extraction of…

Information Retrieval · Computer Science 2017-09-07 Shashank Gupta , Sachin Pawar , Nitin Ramrakhiyani , Girish Palshikar , Vasudeva Varma

Despite extensive safety assessments of drugs prior to their introduction to the market, certain adverse drug reactions (ADRs) remain undetected. The primary objective of pharmacovigilance is to identify these ADRs (i.e., signals). In…

Methodology · Statistics 2024-04-23 Louis Dijkstra , Tania Schink , Ronja Foraita

With the increase in popularity of deep learning models for natural language processing (NLP) tasks, in the field of Pharmacovigilance, more specifically for the identification of Adverse Drug Reactions (ADRs), there is an inherent need for…

Information Retrieval · Computer Science 2020-04-01 Ramya Tekumalla , Juan M. Banda

Timely and accurate extraction of Adverse Drug Events (ADE) from biomedical literature is paramount for public safety, but involves slow and costly manual labor. We set out to improve drug safety monitoring (pharmacovigilance, PV) through…

Post--marketing pharmacovigilance is essential for identifying adverse drug reactions (ADRs) that elude detection during pre--marketing clinical trials. This study explores a novel approach that integrates an adverse event (AE) ontology…

Clinical trials are the basis of Evidence-Based Medicine. Trial results are reviewed by experts and consensus panels for producing meta-analyses and clinical practice guidelines. However, reviewing these results is a long and tedious task,…

Computers and Society · Computer Science 2021-04-21 Jean-Baptiste Lamy

Drug synergy arises when the combined impact of two drugs exceeds the sum of their individual effects. While single-drug effects on cell lines are well-documented, the scarcity of data on drug synergy, considering the vast array of…

Quantitative Methods · Quantitative Biology 2024-04-29 Kyriakos Schwarz , Alicia Pliego-Mendieta , Amina Mollaysa , Lara Planas-Paz , Chantal Pauli , Ahmed Allam , Michael Krauthammer

Over 30 papers have proposed to use convolutional neural network (CNN) for AD classification from anatomical MRI. However, the classification performance is difficult to compare across studies due to variations in components such as…

Online health communities are a valuable source of information for patients and physicians. However, such user-generated resources are often plagued by inaccuracies and misinformation. In this work we propose a method for automatically…

Artificial Intelligence · Computer Science 2017-05-09 Subhabrata Mukherjee , Gerhard Weikum , Cristian Danescu-Niculescu-Mizil

Identification and verification of molecular properties such as side effects is one of the most important and time-consuming steps in the process of molecule synthesis. For example, failure to identify side effects before submission to…

Quantitative Methods · Quantitative Biology 2024-04-12 Collin Beaudoin , Koustubh Phalak , Swaroop Ghosh

Adverse reactions caused by drugs following their release into the market are among the leading causes of death in many countries. The rapid growth of electronically available health related information, and the ability to process large…

Computation and Language · Computer Science 2016-10-11 Abbas Chokor , Abeed Sarker , Graciela Gonzalez

Side effects of prescribed medications are a common occurrence. Electronic healthcare databases present the opportunity to identify new side effects efficiently but currently the methods are limited due to confounding (i.e. when an…

Databases · Computer Science 2016-11-17 Jenna M. Reps , Uwe Aickelin , Jiangang Ma , Yanchun Zhang

The Russian Drug Reaction Corpus (RuDReC) is a new partially annotated corpus of consumer reviews in Russian about pharmaceutical products for the detection of health-related named entities and the effectiveness of pharmaceutical products.…

Computation and Language · Computer Science 2023-11-21 Elena Tutubalina , Ilseyar Alimova , Zulfat Miftahutdinov , Andrey Sakhovskiy , Valentin Malykh , Sergey Nikolenko