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Related papers: Time-optimal control strategies in SIR epidemic mo…

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We propose and study a compartmental model for epidemiology with human behavioral effects. Specifically, our model incorporates governmental prevention measures aimed at lowering the disease infection rate, but we split the population into…

Systems and Control · Electrical Eng. & Systems 2026-02-16 Chloe Ngo , Christian Parkinson , Weinan Wang

When effective medical treatment and vaccination are not available, non-pharmaceutical interventions such as social distancing, home quarantine and far-reaching shutdown of public life are the only available strategies to prevent the spread…

Populations and Evolution · Quantitative Biology 2020-08-19 Markus Kantner , Thomas Koprucki

This article considers a discrete-time robust optimal control problem on matrix Lie groups. The underlying system is assumed to be perturbed by exogenous unmeasured bounded disturbances, and the control problem is posed as a min-max optimal…

Optimization and Control · Mathematics 2020-07-28 Anant A. Joshi , Debasish Chatterjee , Ravi N. Banavar

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

Populations and Evolution · Quantitative Biology 2020-05-04 Andrew Lesniewski

This work will study an optimal control problem describing the two-strain SEIR epidemic model. The studied model is in the form of six nonlinear differential equations illustrating the dynamics of the susceptibles and the exposed, the…

Populations and Evolution · Quantitative Biology 2024-04-29 Karam Allali , Mouhamadou A. M. T. Balde , Babacar M. Ndiaye

We apply optimal control theory to a generalized SEIR-type model. The proposed system has three controls, representing social distancing, preventive means, and treatment measures to combat the spread of the COVID-19 pandemic. We analyze…

Optimization and Control · Mathematics 2021-12-10 Mohamed Abdelaziz Zaitri , Mohand Ouamer Bibi , Delfim F. M. Torres

A problem of computing time-fuel optimal control for state transfer of a single input linear time invariant (LTI) system to the origin is considered. The input is assumed to be bounded. Since, the optimal control is bang-off-bang in nature,…

Optimization and Control · Mathematics 2021-02-23 Rajasree Sarkar , Deepak U. Patil , Indra Narayan Kar

We study the impact of parameter estimation and state measurement errors on a control framework for optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic…

Systems and Control · Electrical Eng. & Systems 2024-08-08 Baike She , Lei Xin , Shreyas Sundaram , Philip E. Paré

In the context of epidemiology, policies for disease control are often devised through a mixture of intuition and brute-force, whereby the set of logically conceivable policies is narrowed down to a small family described by a few…

Populations and Evolution · Quantitative Biology 2021-10-04 Miguel Navascues , Costantino Budroni , Yelena Guryanova

This paper investigates optimal vaccination strategies in a metapopulation epidemic model. We consider a linear cost to better capture operational considerations, such as the total number of vaccines or hospitalizations, in contrast to the…

Optimization and Control · Mathematics 2025-06-03 Lucas Machado Moschen , Maria Soledad Aronna

This work focuses on optimal controls of a class of stochastic SIS epidemic models under regime switching. By assuming that a decision maker can either influence the infectivity period or isolate infected individuals, our aim is to minimize…

Optimization and Control · Mathematics 2021-01-12 Ky Tran , George Yin

During a pandemic, there are conflicting demands arising from public health and economic cost. Lockdowns are a common way of containing infections, but they adversely affect the economy. We study the question of how to minimise the economic…

Populations and Evolution · Quantitative Biology 2021-04-28 Joseph Samuel , Supurna Sinha

Optimizing the impact on the economy of control strategies aiming at containing the spread of COVID-19 is a critical challenge. We use daily new case counts of COVID-19 patients reported by local health administrations from different…

Populations and Evolution · Quantitative Biology 2021-03-12 Afroza Shirin , Yen Ting Lin , Francesco Sorrentino

Stochastic models are widely used to investigate the spread of epidemics in a complex environment. This paper extends a deterministic SAIRS epidemic model to a stochastic case with limited patient capacity and exposure. We first study the…

Probability · Mathematics 2024-05-20 Xiaohui Zhang , Zhiming Li , Shenglong Chen , Jikai Yang

This paper presents a provably optimal, real-time capable energy management policy for race cars that provides simple human-driver-implementable control cues. Specifically, we first formulate the energy-constrained minimum-lap-time control…

Optimization and Control · Mathematics 2026-03-04 Erik van den Eshof , Wytze de Vries , Mauro Salazar

In this paper, we study the optimal control for an SEIR model adapted to the vaccination strategy of susceptible individuals. There are factors associated with a vaccination campaign that make this strategy not only a public health issue…

Optimization and Control · Mathematics 2024-11-08 Nelson L. Santos Junior , João A. M. Gondim

In this work we present a mathematical model that integrates the epidemiological dynamics of a vector-borne disease (SIR-SI) with Lotka Volterra predator prey ecological interactions. The study analyzes how the presence of natural predators…

Optimization and Control · Mathematics 2026-02-09 Rocio Balderrama , Ignacio Ceresa Dussel , Constanza Sanchez de la Vega

This paper introduces a spatiotemporal SEIQR epidemic model governed by a system of reaction-diffusion partial differential equations that incorporates optimal control strategies. The model captures the transmission dynamics of an…

Dynamical Systems · Mathematics 2025-07-29 Achraf Zinihi , Matthias Ehrhardt , Moulay Rchid Sidi Ammi

In this work, we investigate a VS-EIAR epidemiological model that incorporates vaccinated individuals $\{V_i : i = 1, \ldots, n\}$, where $n \in \mathbb{N}^{*}$. The dynamics of the VS-EIAR model are governed by a system of ordinary…

Dynamical Systems · Mathematics 2025-07-16 Mamadou Abdoul Diop , Mohammed Elghandouri , Khalil Ezzinbi

This paper provides necessary conditions of optimality for optimal control problems with time delays in both state and control variables. Different versions of the necessary conditions cover fixed end-time problems and, under additional…

Dynamical Systems · Mathematics 2017-01-09 Andrea Boccia , Richard B. Vinter