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In an age of increasingly large data sets, investigators in many different disciplines have turned to clustering as a tool for data analysis and exploration. Existing clustering methods, however, typically depend on several nontrivial…

Quantitative Methods · Quantitative Biology 2009-11-11 Noam Slonim , Gurinder Singh Atwal , Gasper Tkacik , William Bialek

We study the stability of posterior predictive inferences to the specification of the likelihood model and perturbations of the data generating process. In modern big data analyses, useful broad structural judgements may be elicited from…

Methodology · Statistics 2024-04-30 Jack Jewson , Jim Q. Smith , Chris Holmes

To make informed decisions in natural environments that change over time, humans must update their beliefs as new observations are gathered. Studies exploring human inference as a dynamical process that unfolds in time have focused on…

Neurons and Cognition · Quantitative Biology 2022-03-03 Arthur Prat-Carrabin , Robert C. Wilson , Jonathan D. Cohen , Rava Azeredo da Silveira

Regression methods dominate the practice of biostatistical analysis, but biostatistical training emphasises the details of regression models and methods ahead of the purposes for which such modelling might be useful. More broadly,…

Methodology · Statistics 2024-09-12 John B. Carlin , Margarita Moreno-Betancur

Statistically sound pattern discovery harnesses the rigour of statistical hypothesis testing to overcome many of the issues that have hampered standard data mining approaches to pattern discovery. Most importantly, application of…

Methodology · Statistics 2019-01-07 Wilhelmiina Hämäläinen , Geoffrey I. Webb

There is significant growth and interest in the use of synthetic data as an enabler for machine learning in environments where the release of real data is restricted due to privacy or availability constraints. Despite a large number of…

Machine Learning · Computer Science 2020-11-25 Harrison Wilde , Jack Jewson , Sebastian Vollmer , Chris Holmes

As artificial intelligence and machine learning tools become more accessible, and scientists face new obstacles to data collection (e.g., rising costs, declining survey response rates), researchers increasingly use predictions from…

Machine Learning · Statistics 2025-12-08 Stephen Salerno , Kentaro Hoffman , Awan Afiaz , Anna Neufeld , Tyler H. McCormick , Jeffrey T. Leek

Reachability analysis, in general, is a fundamental method that supports formally-correct synthesis, robust model predictive control, set-based observers, fault detection, invariant computation, and conformance checking, to name but a few.…

Systems and Control · Electrical Eng. & Systems 2020-11-17 Niklas Kochdumper , Bastian Schürmann , Matthias Althoff

How can we draw trustworthy scientific conclusions? One criterion is that a study can be replicated by independent teams. While replication is critically important, it is arguably insufficient. If a study is biased for some reason and other…

Methodology · Statistics 2025-02-06 Yujin Jeong , Dominik Rothenhäusler

Selection bias arises when the probability that an observation enters a dataset depends on variables related to the quantities of interest, leading to systematic distortions in estimation and uncertainty quantification. For example, in…

Data can be collected in scientific studies via a controlled experiment or passive observation. Big data is often collected in a passive way, e.g. from social media. In studies of causation great efforts are made to guard against bias and…

Methodology · Statistics 2018-11-21 Elena Pesce , Eva Riccomagno , Henry P. Wynn

We define the concept of dependence among multiple variables using maximum entropy techniques and introduce a graphical notation to denote the dependencies. Direct inference of information theoretic quantities from data uncovers…

Quantitative Methods · Quantitative Biology 2007-07-13 Ilya Nemenman

Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a…

Populations and Evolution · Quantitative Biology 2012-07-25 Christoph Adami

Information flow analysis has largely ignored the setting where the analyst has neither control over nor a complete model of the analyzed system. We formalize such limited information flow analyses and study an instance of it: detecting the…

Cryptography and Security · Computer Science 2014-05-13 Michael Carl Tschantz , Amit Datta , Anupam Datta , Jeannette M. Wing

Provenance is information recording the source, derivation, or history of some information. Provenance tracking has been studied in a variety of settings; however, although many design points have been explored, the mathematical or semantic…

Databases · Computer Science 2009-12-22 James Cheney , Amal Ahmed , Umut Acar

In order to develop machine learning and deep learning models that take into account the guidelines and principles of trustworthy AI, a novel information theoretic trustworthy AI framework is introduced. A unified approach to…

Machine Learning · Computer Science 2022-04-13 Mohit Kumar , Bernhard A. Moser , Lukas Fischer , Bernhard Freudenthaler

In this paper, we initiate a principled study of how the generalization properties of approximate differential privacy can be used to perform adaptive hypothesis testing, while giving statistically valid $p$-value corrections. We do this by…

Machine Learning · Computer Science 2016-09-12 Ryan Rogers , Aaron Roth , Adam Smith , Om Thakkar

The success of AI models relies on the availability of large, diverse, and high-quality datasets, which can be challenging to obtain due to data scarcity, privacy concerns, and high costs. Synthetic data has emerged as a promising solution…

Computation and Language · Computer Science 2024-08-13 Ruibo Liu , Jerry Wei , Fangyu Liu , Chenglei Si , Yanzhe Zhang , Jinmeng Rao , Steven Zheng , Daiyi Peng , Diyi Yang , Denny Zhou , Andrew M. Dai

Econometricians have usefully separated study of estimation into identification and statistical components. Identification analysis, which assumes knowledge of the probability distribution generating observable data, places an upper bound…

Econometrics · Economics 2025-09-03 Charles F. Manski

The principles of statistical mechanics and information theory play an important role in learning and have inspired both theory and the design of numerous machine learning algorithms. The new aspect in this paper is a focus on integrating…

Data Analysis, Statistics and Probability · Physics 2015-05-13 Susanne Still