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Holographic optical coherence tomography (OCT) is a powerful imaging technique, but its ability to reveal low-reflectivity features is limited. In this study, we performed holographic OCT by incoherently averaging volumes with changing…

Structured illumination can reject out-of-focus signal from a sample, enabling high-speed and high-contrast imaging over large areas with widefield detection optics. Currently, this optical-sectioning technique is limited by image…

In today's clinics, a cellular-resolution view of the cornea can be achieved only with an in vivo confocal microscope (IVCM) in contact with the eye. Here, we present a common-path Full-field/Spectral-domain OCT microscope (FF/SD OCT),…

Endoscopic optical coherence tomography (OCT) is a valuable tool for providing diagnostic images of internal organs and guiding interventions in real time. Miniaturized OCT endoscopes are essential for imaging small and convoluted luminal…

Instrumentation and Detectors · Physics 2023-11-28 Chao Xu , Xin Guan , Syeda Aimen Abbasi , Neng Xia , To Ngai , Li Zhang , Ho-Pui Ho , Sze Hang Calvin Ng , Wu Yuan

Traditional full-field optical coherence tomography (FF-OCT) is effective for rapid cross-sectional imaging but often suffers from incoherent signals due to imbalanced light intensities between the sample and reference arms. While the…

Optics · Physics 2024-10-17 Youlong Fan , Qingye Hu , Zhongping Wang , Zengming Zhang , Xiantao Wei

We demonstrate Optical-Resolution Photoacoustic Microscopy (OR-PAM), where the optical field is focused and scanned using Digital Phase Conjugation (DPC) through a multimode fiber. The focus is scanned across the field of view using digital…

We propose a new technique, called quantum optical coherence tomography (QOCT), for carrying out tomographic measurements with dispersion-cancelled resolution. The technique can also be used to extract the frequency-dependent refractive…

Optical frequency combs have revolutionised time and frequency metrology [1, 2]. The advent of microresonator-based frequency combs ('microcombs' [3-5]) is set to lead to the miniaturisation of devices that are ideally suited to a wide…

We suggest a new method for quantum optical control with nanoscale resolution. Our method allows for coherent far-field manipulation of individual quantum systems with spatial selectivity that is not limited by the wavelength of radiation…

Quantum Physics · Physics 2008-03-10 Alexey V. Gorshkov , Liang Jiang , Markus Greiner , Peter Zoller , Mikhail D. Lukin

Coherent diffraction imaging (CDI) is high-resolution lensless microscopy that has been applied to image a wide range of specimens using synchrotron radiation, X-ray free electron lasers, high harmonic generation, soft X-ray laser and…

Optics · Physics 2014-01-23 Jose A Rodriguez , Rui Xu , Chien-Chun Chen , Yunfei Zou , Jianwei Miao

The ability to detect and identify molecules at high sensitivity without the use of labels or capture agents is important for medical diagnostics, threat identification, environmental monitoring, and basic science. Microtoroid optical…

Optics · Physics 2022-10-17 Gwangho Choi , Adley Gin , Judith Su

A fundamental challenge in endoscopy is how to fabricate a small fiber-optic probe that can achieve comparable function to probes with large, complicated optics (e.g., high resolution and extended depth of focus). To achieve high resolution…

Comb-based optical arbitrary waveform measurement (OAWM) techniques can overcome the bandwidth limitations of conventional coherent detection schemes and may have disruptive impact on a wide range of scientific and industrial applications.…

Signal Processing · Electrical Eng. & Systems 2023-10-30 Daniel Drayss , Dengyang Fang , Christoph Füllner , Wolfgang Freude , Sebastian Randel , Christian Koos

Current optoacoustic microscopy configurations often have narrow focal ranges that limit their use for fast volumetric imaging applications. Here, the focal range of optoacoustic microscopes is extended by matching the elongated optical…

Optics · Physics 2021-04-15 Zakiullah Ali , Christian Zakian , Vasilis Ntziachristos

Ultrabroadband electro-optic sampling with few-cycle optical pulses is known to be an extremely sensitive technique to detect electric field amplitudes. By combining this method with dual-comb spectroscopy and with a new class of ultrafast…

Label-free microscopy exploits light scattering to obtain a three-dimensional image of biological tissues. However, light propagation is affected by aberrations and multiple scattering, which drastically degrade the image quality and limit…

With the rapid development of spaceborne imaging techniques, object detection in optical remote sensing imagery has drawn much attention in recent decades. While many advanced works have been developed with powerful learning algorithms, the…

Computer Vision and Pattern Recognition · Computer Science 2019-12-19 Xin Wu , Danfeng Hong , Jiaojiao Tian , Jocelyn Chanussot , Wei Li , Ran Tao

The proliferation of mobile Internet and connected devices, offering a variety of services at different levels of performance, represents a major challenge for the fifth generation wireless networks and beyond. This requires a paradigm…

Information Theory · Computer Science 2017-04-26 Hanaa Marshoud , Sami Muhaidat , Paschalis C. Sofotasios , Sajjad Hussain , Muhammad Ali Imran , Bayan S. Sharif

Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and…

Medical Physics · Physics 2019-07-02 Cerine Lal , Hrebesh M Subhash , Sergey Alexandrov , Martin J Leahy

Oblique plane microscopy (OPM) offers 3D optically sectioned imaging with high spatial- and temporal-resolution while enabling conventional sample mounting. The technique uses a concatenation of three microscopes, two for remote focusing…