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Optical coherence tomography (OCT) is a powerful biomedical imaging technology that relies on the coherent detection of backscattered light to image tissue morphology in vivo. As a consequence, OCT is susceptible to coherent noise (speckle…

Full-field x-ray microscopy using x-ray objectives has become a mainstay of the biological and materials sciences. However, the inefficiency of existing objectives at x-ray energies above 15 keV has limited the technique to weakly absorbing…

We realize a scanning probe microscope using single trapped $^{87}$Rb atoms to measure optical fields with subwavelength spatial resolution. Our microscope operates by detecting fluorescence from a single atom driven by near-resonant light…

Atomic Physics · Physics 2022-03-02 Emma Deist , Justin A. Gerber , Yue-Hui Lu , Johannes Zeiher , Dan M. Stamper-Kurn

Label-free nonlinear optical microscopy has become a powerful tool for biomedical research. However, the possible photodamage risk hinder further clinical applications. To reduce these adverse effects, we constructed a new platform of…

Optics · Physics 2022-10-26 Geng Wang , Stephen A. Boppart , Haohua Tu

Structured Illumination Microscopy (SIM) overcomes the optical diffraction limit by folding high-frequency components into the baseband of the optical system, where they can be extracted and then repositioned to their original location in…

Optics · Physics 2024-11-18 Doron Shterman , Guy Bartal

The Optical Monitoring Camera (OMC) onboard INTEGRAL provides photometry in the Johnson V-band. With an aperture of 50 mm and a field of view of 5deg x 5deg, OMC is able to detect optical sources brighter than V~18, from a previously…

Instrumentation and Methods for Astrophysics · Physics 2015-06-11 J. Alfonso-Garzón , A. Domingo , J. M. Mas-Hesse , A. Giménez

We report the experimental realization of a quantum silicon carbide microscope (QSiCM) and demonstrate its functionality by imaging magnetic fields generated by electrical currents. We employ a dual-frequency sensing protocol to enhance the…

Quantum Physics · Physics 2025-09-19 A. Suhana , T. A. U. Svetikova , C. Schneider , M. Helm , A. N. Anisimov , G. V. Astakhov

High-resolution optical microscopy suffers from a low contrast in scattering media where a multiply scattered wave obscures a ballistic wave used for image formation. To extend the imaging depth, various gating operations - confocal,…

Optics · Physics 2018-11-08 Mooseok Jang , Hakseok Ko , Won Kyu Lee , Jae-Seung Lee , Wonshik Choi

Laser-based lensless digital holographic microscopy (LDHM) is often spoiled by considerable coherent noise factor. We propose a novel LDHM method with significantly limited coherent artifacts, e.g., speckle noise and parasitic interference…

This dissertation relates to the transition of the state of the art of swept source optical coherence tomography (SS-OCT) systems to a new realm in which the image acquisition speed is improved by an order of magnitude. With the aid of a…

Image and Video Processing · Electrical Eng. & Systems 2020-02-21 Amir Tofighi Zavareh

Automated label-free quantitative imaging of biological samples can greatly benefit high throughput diseases diagnosis. Digital holographic microscopy (DHM) is a powerful quantitative label-free imaging tool that retrieves structural…

Quantum imaging exploits the spatial correlations between photons to image object features with a higher resolution than a corresponding classical light source could achieve. Using a quantum correlated $N$-photon state, the method of…

Three-dimensional ultrasound localization microscopy (ULM) enables comprehensive visualization of the vasculature, thereby improving diagnostic reliability. Nevertheless, its clinical translation remains challenging, as the exponential…

A universal methodology for coding-decoding the complex amplitude field of an imaged sample in coherent microscopy is presented, where no restrictions on any of the two interferometric beams are required. Thus, the imaging beam can be…

Asymmetrically clipped optical orthogonal frequency-division multiplexing (ACO-OFDM) is a technique that sacrifices spectral efficiency in order to transmit an orthogonally frequency-division multiplexed signal over a unipolar channel, such…

Information Theory · Computer Science 2016-03-10 Arthur James Lowery

Using spectrally correlated photon pairs instead of classical laser light and coincidence detection instead of light intensity detection, Quantum Optical Coherence Tomography (Q-OCT) outperforms classical OCT in several experimental terms.…

Quantum Physics · Physics 2025-10-06 Sylwia M. Kolenderska , Crislane Vieira de Brito , Piotr Kolenderski

We present a conceptual design for a new X-ray all sky monitor (ASM). Compared with previous ASMs, its salient features are: (1) it has a focusing capability that increases the signal to background ratio by a factor of 3; (2) it has a…

Astrophysics · Physics 2008-02-03 W. Zhang , R. Petre , A. N. Peele , K. Jahoda , F. E. Marshall , Y. Soong , N. E. White

Wide-field mid-infrared photothermal (MIP) imaging offers rapid labelfree chemical contrast for biomedical and polymer analysis. However, its field of view (FOV) is limited by the pulse intensity of conventional infrared lasers. Here, we…

Anterior Segment Optical Coherence Tomography (AS-OCT) is an emerging imaging technique with great potential for diagnosing anterior uveitis, a vision-threatening ocular inflammatory condition. A hallmark of this condition is the presence…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Boyu Chen , Ameenat L. Solebo , Daqian Shi , Jinge Wu , Paul Taylor

Detecting multiple unknown objects in noisy data is a key problem in many scientific fields, such as electron microscopy imaging. A common model for the unknown objects is the linear subspace model, which assumes that the objects can be…

Statistics Theory · Mathematics 2024-05-02 Amitay Eldar , Keren Mor Waknin , Samuel Davenport , Tamir Bendory , Armin Schwartzman , Yoel Shkolnisky
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