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Related papers: FRAMR-EMR: Framework for Prognostic Predictive Mod…

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The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Missing values in electronic health record (EHR) data pose a significant challenge for epidemiologic research. Traditional methods for handling missing data, like mean imputation, may introduce bias. Multiple imputation (MI) offers a…

Managing patients with chronic diseases is a major and growing healthcare challenge in several countries. A chronic condition, such as diabetes, is an illness that lasts a long time and does not go away, and often leads to the patient's…

Machine Learning · Computer Science 2020-03-23 Rafael T. Sousa , Lucas A. Pereira , Anderson S. Soares

Electronic health records (EHRs) contain patients' heterogeneous data that are collected from medical providers involved in the patient's care, including medical notes, clinical events, laboratory test results, symptoms, and diagnoses. In…

Artificial Intelligence · Computer Science 2024-11-12 Shuai Niu , Yunya Song , Qing Yin , Yike Guo , Xian Yang

This paper focuses on drawing statistical inference based on a novel variant of maxima or minima nomination sampling (NS) designs. These sampling designs are useful for obtaining more representative sample units from the tails of the…

Methodology · Statistics 2021-06-01 Zeinab Akbari Ghamsari , Ehsan Zamanzade , Majid Asadi

As machine learning continues to gain momentum in the neuroscience community, we witness the emergence of novel applications such as diagnostics, characterization, and treatment outcome prediction for psychiatric and neurological disorders,…

Computer Vision and Pattern Recognition · Computer Science 2018-04-27 Maxim Sharaev , Alexander Andreev , Alexey Artemov , Alexander Bernstein , Evgeny Burnaev , Ekaterina Kondratyeva , Svetlana Sushchinskaya , Renat Akzhigitov

Knee Osteoarthritis (KOA) is a highly prevalent chronic musculoskeletal condition with no currently available treatment. The manifestation of KOA is heterogeneous and prediction of its progression is challenging. Current literature suggests…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

The event-based model (EBM) for data-driven disease progression modeling estimates the sequence in which biomarkers for a disease become abnormal. This helps in understanding the dynamics of disease progression and facilitates early…

Computer Vision and Pattern Recognition · Computer Science 2017-02-22 Vikram Venkatraghavan , Esther Bron , Wiro Niessen , Stefan Klein

Haemodynamic indices derived from Computational Fluid Dynamics (CFD), such as Time-averaged Wall Shear Stress (TAWSS) and Oscillatory Shear Index (OSI), are closely associated with restenosis risk in Peripheral Arterial Disease (PAD).…

Electronic health records (EHRs) contain structured and unstructured data of significant clinical and research value. Various machine learning approaches have been developed to employ information in EHRs for risk prediction. The majority of…

Clinical risk prediction using electronic health records (EHRs) is vital to facilitate timely interventions and clinical decision support. However, modeling heterogeneous and irregular temporal EHR data presents significant challenges. We…

Machine Learning · Computer Science 2025-11-04 Kun-Wei Lin , Yu-Chen Kuo , Hsin-Yao Wang , Yi-Ju Tseng

Most automated electronic medical record (EMR) pipelines remain output-oriented: they transcribe, extract, and summarize after the consultation, but they do not explicitly model what is already known, what is still missing, which…

Artificial Intelligence · Computer Science 2026-03-19 Zhenhai Pan , Yan Liu , Jia You

We present a self-supervised, time-to-event (TTE) foundation model called MOTOR (Many Outcome Time Oriented Representations) which is pretrained on timestamped sequences of events in electronic health records (EHR) and health insurance…

Machine Learning · Computer Science 2023-12-06 Ethan Steinberg , Jason Fries , Yizhe Xu , Nigam Shah

Many real-world Electronic Health Record (EHR) data contains a large proportion of missing values. Leaving substantial portion of missing information unaddressed usually causes significant bias, which leads to invalid conclusion to be…

Machine Learning · Computer Science 2020-11-04 Lucas J. Liu , Hongwei Zhang , Jianzhong Di , Jin Chen

Motivation: Electronic health record (EHR) data provides a new venue to elucidate disease comorbidities and latent phenotypes for precision medicine. To fully exploit its potential, a realistic data generative process of the EHR data needs…

Machine Learning · Computer Science 2021-05-05 Ziyang Song , Xavier Sumba Toral , Yixin Xu , Aihua Liu , Liming Guo , Guido Powell , Aman Verma , David Buckeridge , Ariane Marelli , Yue Li

Introduction Schizophrenia is a severe mental disorder, and early diagnosis is key to improving outcomes. Its complexity makes predicting onset and progression challenging. EEG has emerged as a valuable tool for studying schizophrenia, with…

Signal Processing · Electrical Eng. & Systems 2024-10-29 Gideon Vos , Maryam Ebrahimpour , Liza van Eijk , Zoltan Sarnyai , Mostafa Rahimi Azghadi

Electronic health records (EHRs) provide a powerful basis for predicting the onset of health outcomes. Yet EHRs primarily capture in-clinic events and miss aspects of daily behavior and lifestyle containing rich health information. Consumer…

Multinomial prediction models (MPMs) have a range of potential applications across healthcare where the primary outcome of interest has multiple nominal or ordinal categories. However, the application of MPMs is scarce, which may be due to…

Longitudinal electronic health record (EHR) data offer opportunities to study biomarker trajectories; however, association estimates-the primary inferential target-from standard models designed for regular observation times may be biased by…

Methodology · Statistics 2026-02-18 Cheng-Han Yang , Xu Shi , Bhramar Mukherjee

The estimated Glomerular Filtration Rate (eGFR) is an essential indicator of kidney function in clinical practice. Although traditional equations and Machine Learning (ML) models using clinical and laboratory data can estimate eGFR,…

Machine Learning · Computer Science 2024-09-05 Chih-Yuan Li , Jun-Ting Wu , Chan Hsu , Ming-Yen Lin , Yihuang Kang