The estimated Glomerular Filtration Rate (eGFR) is an essential indicator of kidney function in clinical practice. Although traditional equations and Machine Learning (ML) models using clinical and laboratory data can estimate eGFR, accurately predicting future eGFR levels remains a significant challenge for nephrologists and ML researchers. Recent advances demonstrate that Large Language Models (LLMs) and Large Multimodal Models (LMMs) can serve as robust foundation models for diverse applications. This study investigates the potential of LMMs to predict future eGFR levels with a dataset consisting of laboratory and clinical values from 50 patients. By integrating various prompting techniques and ensembles of LMMs, our findings suggest that these models, when combined with precise prompts and visual representations of eGFR trajectories, offer predictive performance comparable to existing ML models. This research extends the application of foundation models and suggests avenues for future studies to harness these models in addressing complex medical forecasting challenges.
Cite
@article{arxiv.2409.02530,
title = {Understanding eGFR Trajectories and Kidney Function Decline via Large Multimodal Models},
author = {Chih-Yuan Li and Jun-Ting Wu and Chan Hsu and Ming-Yen Lin and Yihuang Kang},
journal= {arXiv preprint arXiv:2409.02530},
year = {2024}
}
Comments
This preprint version includes corrections of typographical errors related to numerical values in Table 2, which were present in the version published at the BDH workshop in MIPR 2024. These corrections do not affect the overall conclusions of the study