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Flow-based microfluidic biochips have attracted much atten- tion in the EDA community due to their miniaturized size and execution efficiency. Previous research, however, still follows the traditional computing model with a dedicated…

Emerging Technologies · Computer Science 2017-05-16 Chunfeng Liu , Bing Li , Hailong Yao , Paul Pop , Tsung-Yi Ho , Ulf Schlichtmann

Microfluidic biochips are replacing the conventional biochemical analysers integrating the necessary functions on-chip. We are interested in Flow-Based Microfluidic Biochips (FBMB), where a continuous flow of liquid is manipulated using…

Emerging Technologies · Computer Science 2025-05-07 Alexander Schneider , Jan Madsen , Paul Pop

Microfluidics-based biochips are soon expected to revolutionize clinical diagnosis, DNA sequencing, and other laboratory procedures involving molecular biology. Most microfluidic biochips are based on the principle of continuous fluid flow…

Hardware Architecture · Computer Science 2011-11-09 Fei Su , Krishnendu Chakrabarty

Given the ever-increasing advances of digital microfluidic biochips and their application in a wide range of areas including bio-chemistry experiments, diagnostics, and monitoring purposes like air and water quality control and etc.,…

Emerging Technologies · Computer Science 2020-01-01 Alireza Abdoli

Microfluidics, the study of fluids in microscopic channels, has led to important advances in fields as diverse as microelectronics, biotechnology and chemistry. Microfluidic research is primarily based on the use of microfluidic chips,…

Systems and Control · Electrical Eng. & Systems 2024-07-15 Jorge Vicente Martinez , Edgar Ramirez-Laboreo , Pablo Calderon Gil

Microfluidics and lab-on-a-chip technologies have made it possible to manipulate small volume liquids with unprecedented resolution, automation and integration. However, most current microfluidic systems still rely on bulky off-chip…

Instrumentation and Detectors · Physics 2014-05-22 Baichen Li , Lin Li , Allan Guan , Quan Dong , Kangcheng Ruan , Ronggui Hu , Zhenyu Li

Sample preparation is an indispensable component of almost all biochemical protocols, and it involves, among others, making dilutions and mixtures of fluids in certain ratios. Recent microfluidic technologies offer suitable platforms for…

Emerging Technologies · Computer Science 2019-01-03 Sudip Poddar , Robert Wille , Hafizur Rahaman , Bhargab B. Bhattacharya

Inexpensive, portable lab-on-a-chip devices would revolutionize fields like environmental monitoring and global health, but current microfluidic chips are tethered to extensive off-chip hardware. Insects, however, are self-contained and…

Precise manipulation of fluids and objects on the micro scale is seldom a simple task, but nevertheless crucial for many applications in life sciences and chemical engineering. We present a microfluidic chip fabricated in silicon-glass,…

The analysis of nano-and microparticle suspensions with micro systems affords improved space-time yields, selectivity, reaction residence times and conversions capabilities. These capabilities are of primary importance in various fields of…

Instrumentation and Detectors · Physics 2022-01-24 F. Onofri , Isaac Rodríguez-Ruiz , Fabrice Lamadie , Fabrice Onofri

Design of microfluidic biochips has led to newer challenges to the EDA community due to the availability of various flow-based architectures and the need for catering to diverse applications such as sample preparation, personalized…

Emerging Technologies · Computer Science 2021-07-28 Tapalina Banerjee , Sudip Poddar , Tsung-Yi Ho , Bhargab B. Bhattacharya

We describe an approach for modeling fluid concentration profiles in grid-based microfluidic chips for fluid mixing. This approach provides an algorithm that predicts fluid concentrations at the chip outlets. Our algorithm significantly…

Computational Engineering, Finance, and Science · Computer Science 2019-11-19 Huong Luu , Marek Chrobak

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

Soft Condensed Matter · Physics 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture

We address the problem of designing micro-fluidic chips for sample preparation, which is a crucial step in many experimental processes in chemical and biological sciences. One of the objectives of sample preparation is to dilute the sample…

Data Structures and Algorithms · Computer Science 2019-11-07 Miguel Coviello Gonzalez , Marek Chrobak

Biomedical and biochemical processes in paper-based microfluidic devices often deal with mixing of two analytes to perform important functions. Uniform mixing of analytes in paper matrix is a challenging proposition, often necessitating…

To facilitate the use and portability of Lab on a chip technology, it is desirable to avoid the use of bulky electronic systems for flow control. Developed self-powered microsystems typically move only small volumes of fluid performing up…

Mixing is one of the basic functions which automated lab-on-chips require for the effective management of liquid samples. In this paper we report on the working principle, design, fabrication and experimental characterization of a…

Soft Condensed Matter · Physics 2010-12-14 M. Campisi , D. Accoto , F. Damiani , P. Dario

Micro/nanoporous membranes have been used extensively in biological and medical applications associated with filtration, particle sorting, cell separation, and real-time sensing. Expanding its applications to microfluidics offers several…

Digital Microfluidic Biochips consist of Two Dimensional microarrays that are integrated with different healthcare related cyberphysical systems and expected to be used extensively in near future. Thus, faster and error-free synthesis…

Emerging Technologies · Computer Science 2018-04-10 Sarit Chakraborty , Susanta Chakraborty

Investigations of free-standing liquid films enjoy an increasing popularity due to their relevance for many fundamental and applied scientific problems. They constitute soap bubbles and foams, serve as membranes for gas transport or as…

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