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Evolution is often understood through genetic mutations driving changes in an organism's fitness, but there is potential to extend this understanding beyond the genetic code. We propose that natural products - complex molecules central to…

Populations and Evolution · Quantitative Biology 2024-09-11 Sebastian Pagel , Abhishek Sharma , Leroy Cronin

In order to make a case for or against a trend in the evolution of complexity in biological evolution, complexity needs to be both rigorously defined and measurable. A recent information-theoretic (but intuitively evident) definition…

Biological Physics · Physics 2016-09-08 Christoph Adami , Charles Ofria , Travis C. Collier

The search for extraterrestrial life in the Solar System and beyond is a key science driver in astrobiology, planetary science, and astrophysics. A critical step is the identification and characterization of potential habitats, both to…

Despite the common misconception of nearly static organisms, plants do interact continuously with the environment and with each other. It is fair to assume that during their evolution they developed particular features to overcome problems…

Populations and Evolution · Quantitative Biology 2016-02-19 Gianna Vivaldo , Elisa Masi , Camilla Pandolfi , Stefano Mancuso , Guido Caldarelli

An enduring challenge in computational biology is to balance data quality and quantity with model complexity. Tools such as identifiability analysis and information criterion have been developed to harmonise this juxtaposition, yet cannot…

Quantitative Methods · Quantitative Biology 2022-08-04 Alexander P Browning , Matthew J Simpson

The goal of property testing is to quickly distinguish between objects which satisfy a property and objects that are $\epsilon$-far from satisfying the property. There are now several general results in this area which show that natural…

Combinatorics · Mathematics 2018-04-05 Jacob Fox , Fan Wei

Complex networks are a powerful modeling tool, allowing the study of countless real-world systems. They have been used in very different domains such as computer science, biology, sociology, management, etc. Authors have been trying to…

Social and Information Networks · Computer Science 2014-02-04 Burcu Kantarcı , Vincent Labatut

The multifarious internal workings of organisms are difficult to reconcile with a single feature defining a state of being alive. Indeed, definitions of life rely on emergent properties (growth, capacity to evolve, agency) only symptomatic…

Other Quantitative Biology · Quantitative Biology 2023-08-16 Simon Pierce

Living organisms rely on molecular networks, such as gene circuits and signaling pathways, for information processing and robust decision-making in crowded, noisy environments. Recent advances show that interacting biomolecules…

In this paper we propose an approach for measuring growth of complexity of emerging patterns in complex systems such as cellular automata. We discuss several ways how a metric for measuring the complexity growth can be defined. This…

Cellular Automata and Lattice Gases · Physics 2022-07-22 Hugo Cisneros , Josef Sivic , Tomas Mikolov

We show how complexity theory can be introduced in machine learning to help bring together apparently disparate areas of current research. We show that this new approach requires less training data and is more generalizable as it shows…

Machine Learning · Computer Science 2019-10-10 Santiago Hernández-Orozco , Hector Zenil , Jürgen Riedel , Adam Uccello , Narsis A. Kiani , Jesper Tegnér

Life is commonly described as a self-organized, far-from-equilibrium process that maintains internal order by consuming free energy and exporting entropy. This thermodynamic view underlies diverse theoretical frameworks -- from autopoiesis…

Biological Physics · Physics 2025-12-23 Didier Sornette , Virgile Troude

At the heart of many contemporary theories of life is the concept of biological self-organisation: organisms have to continuously produce and maintain the conditions of their own existence in order to stay alive. The way in which these…

Quantitative Methods · Quantitative Biology 2025-03-17 Emmy Brown , Sean T. Vittadello

Life can be viewed as a localized chemical system that sits on, or in the basin of attraction of, a metastable dynamical attractor state that remains out of equilibrium with the environment. Such a view of life allows that new living states…

Populations and Evolution · Quantitative Biology 2018-01-08 David A. Baum

In the coming years and decades, advanced space- and ground-based observatories will allow an unprecedented opportunity to probe the atmospheres and surfaces of potentially habitable exoplanets for signatures of life. Life on Earth, through…

A phenomenological model of self-organization explaining the emergence of a complexity with features that apparently satisfy the specific criteria usually required for recognizing the appearance of life in laboratory is presented. The…

Adaptation and Self-Organizing Systems · Physics 2007-08-31 Erzilia Lozneanu , Mircea Sanduloviciu

Tools that effectively analyze and compare sequences are of great importance in various areas of applied computational research, especially in the framework of molecular biology. In the present paper, we introduce simple geometric criteria…

Quantitative Methods · Quantitative Biology 2013-08-14 Boris Brimkov , Valentin E. Brimkov

We define a novel quantitative strategy inspired by the ecological notion of nestedness to single out the scale at which innovation complexity emerges from the aggregation of specialized building blocks. Our analysis not only suggests that…

General Economics · Economics 2019-09-13 Emanuele Pugliese , Lorenzo Napolitano , Matteo Chinazzi , Guido Chiarotti

The probability that life spontaneously emerges in a suitable environment (abiogenesis) is one of the major unknowns in astrobiology. Assessing its value is impeded by the lack of an accepted theory for the origin of life, and is further…

Earth and Planetary Astrophysics · Physics 2023-05-10 Amedeo Balbi , Manasvi Lingam