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Live-cell microscopy allows to go beyond measuring average features of cellular populations to observe, quantify and explain biological heterogeneity. Deep Learning-based instance segmentation and cell tracking form the gold standard…

Quantitative Methods · Quantitative Biology 2024-08-09 Richard D. Paul , Johannes Seiffarth , Hanno Scharr , Katharina Nöh

This paper introduces a novel deep learning based approach for vision based single target tracking. We address this problem by proposing a network architecture which takes the input video frames and directly computes the tracking score for…

Computer Vision and Pattern Recognition · Computer Science 2016-07-12 Mengyao Zhai , Mehrsan Javan Roshtkhari , Greg Mori

Fetal magnetic resonance imaging (MRI) is challenged by uncontrollable, large, and irregular fetal movements. It is, therefore, performed through visual monitoring of fetal motion and repeated acquisitions to ensure diagnostic-quality…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Ayush Singh , Seyed Sadegh Mohseni Salehi , Ali Gholipour

Increasing data set sizes of 3D microscopy imaging experiments demand for an automation of segmentation processes to be able to extract meaningful biomedical information. Due to the shortage of annotated 3D image data that can be used for…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Dennis Eschweiler , Richard S. Smith , Johannes Stegmaier

Understanding and extracting the patterns of microscopy images has been a major challenge in the biomedical field. Although trained scientists can locate the proteins of interest within a human cell, this procedure is not efficient and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Hanke Chen

Over the past few years, the rapid development of deep learning technologies for computer vision has significantly improved the performance of medical image segmentation (MedISeg). However, the diverse implementation strategies of various…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Dong Zhang , Yi Lin , Hao Chen , Zhuotao Tian , Xin Yang , Jinhui Tang , Kwang Ting Cheng

Oblique back-illumination capillaroscopy has recently been introduced as a method for high-quality, non-invasive blood cell imaging in human capillaries. To make this technique practical for clinical blood cell counting, solutions for…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Luojie Huang , Gregory N. McKay , Nicholas J. Durr

This paper presents a new deep regression model, which we call DeepDistance, for cell detection in images acquired with inverted microscopy. This model considers cell detection as a task of finding most probable locations that suggest cell…

Computer Vision and Pattern Recognition · Computer Science 2019-08-30 Can Fahrettin Koyuncu , Gozde Nur Gunesli , Rengul Cetin-Atalay , Cigdem Gunduz-Demir

Cell nuclei segmentation is one of the most important tasks in the analysis of biomedical images. With ever-growing sizes and amounts of three-dimensional images to be processed, there is a need for better and faster segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Julian Arz , Peter Sanders , Johannes Stegmaier , Ralf Mikut

Visual object tracking is a significant computer vision task which can be applied to many domains such as visual surveillance, human computer interaction, and video compression. In the literature, researchers have proposed a variety of 2D…

Computer Vision and Pattern Recognition · Computer Science 2013-03-21 Xi Li , Weiming Hu , Chunhua Shen , Zhongfei Zhang , Anthony Dick , Anton van den Hengel

Constructing cell developmental trajectories is a critical task in single-cell RNA sequencing (scRNA-seq) analysis, enabling the inference of potential cellular progression paths. However, current automated methods are limited to…

Computational Geometry · Computer Science 2025-07-31 Qipeng Wang , Shaolun Ruan , Rui Sheng , Yong Wang , Min Zhu , Huamin Qu

Interactive segmentation is a crucial research area in medical image analysis aiming to boost the efficiency of costly annotations by incorporating human feedback. This feedback takes the form of clicks, scribbles, or masks and allows for…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Zdravko Marinov , Paul F. Jäger , Jan Egger , Jens Kleesiek , Rainer Stiefelhagen

How microorganisms respond to and interact with their environment can vary significantly from individual to individual, which can have important microbiological and ecological implications. However, most microscopy techniques can only…

Cell instance segmentation is a new and challenging task aiming at joint detection and segmentation of every cell in an image. Recently, many instance segmentation methods have applied in this task. Despite their great success, there still…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Menghao Li , Wenquan Feng , Shuchang Lyu , Lijiang Chen , Qi Zhao

We study the problem of multi-target tracking and data association in video. We formulate this in terms of selecting a subset of high-quality tracks subject to the constraint that no pair of selected tracks is associated with a common…

Computer Vision and Pattern Recognition · Computer Science 2016-08-10 Shaofei Wang , Steffen Wolf , Charless Fowlkes , Julian Yarkony

The recent trend in multiple object tracking (MOT) is heading towards leveraging deep learning to boost the tracking performance. However, it is not trivial to solve the data-association problem in an end-to-end fashion. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2021-03-29 Peng Dai , Renliang Weng , Wongun Choi , Changshui Zhang , Zhangping He , Wei Ding

Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various biomedical research. Yet conducting this manually is costly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xiaofei Hui , Haoxuan Qu , Hossein Rahmani , Shuohong Wang , Jeff W. Lichtman , Jun Liu

Modeling the 3D structures of cells and tissues is crucial in biology. Sequential cross-sectional images from electron microscopy provide high-resolution intracellular structure information. The segmentation of complex cell structures…

Quantitative Methods · Quantitative Biology 2025-02-14 Jin Kousaka , Atsuko H. Iwane , Yuichi Togashi

Cell detection is the task of detecting the approximate positions of cell centroids from microscopy images. Recently, convolutional neural network-based approaches have achieved promising performance. However, these methods require a…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Kazuya Nishimura , Hyeonwoo Cho , Ryoma Bise

Protein contacts provide key information for the understanding of protein structure and function, and therefore contact prediction from sequences is an important problem. Recent research shows that some correctly predicted long-range…

Quantitative Methods · Quantitative Biology 2020-09-02 Siqi Sun
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