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Deep neural networks (DNN) have been used successfully in many scientific problems for their high prediction accuracy, but their application to genetic studies remains challenging due to their poor interpretability. In this paper, we…

Machine Learning · Computer Science 2021-10-01 Peyman H. Kassani , Fred Lu , Yann Le Guen , Zihuai He

In multi-label classification, the main focus has been to develop ways of learning the underlying dependencies between labels, and to take advantage of this at classification time. Developing better feature-space representations has been…

Machine Learning · Computer Science 2015-02-23 Jesse Read , Fernando Perez-Cruz

We present a novel deep convolutional neural network (DCNN) system for fine-grained image classification, called a mixture of DCNNs (MixDCNN). The fine-grained image classification problem is characterised by large intra-class variations…

Computer Vision and Pattern Recognition · Computer Science 2015-12-01 ZongYuan Ge , Alex Bewley , Christopher McCool , Ben Upcroft , Peter Corke , Conrad Sanderson

For better classification generative models are used to initialize the model and model features before training a classifier. Typically it is needed to solve separate unsupervised and supervised learning problems. Generative restricted…

Machine Learning · Statistics 2019-08-13 Jaehoon Koo , Diego Klabjan

Motivation: Deep learning architectures have recently demonstrated their power in predicting DNA- and RNA-binding specificities. Existing methods fall into three classes: Some are based on Convolutional Neural Networks (CNNs), others use…

Machine Learning · Computer Science 2019-01-31 Ameni Trabelsi , Mohamed Chaabane , Asa Ben Hur

Circular RNAs (circRNAs) are important components of the non-coding RNA regulatory network. Previous circRNA identification primarily relies on high-throughput RNA sequencing (RNA-seq) data combined with alignment-based algorithms that…

Machine Learning · Computer Science 2025-07-14 Tianyou Jiang

In this work, we develop a novel input feature selection framework for ReLU-based deep neural networks (DNNs), which builds upon a mixed-integer optimization approach. While the method is generally applicable to various classification…

Optimization and Control · Mathematics 2023-02-22 Shudian Zhao , Calvin Tsay , Jan Kronqvist

The deep extension of the restricted Boltzmann machine (RBM), known as the deep Boltzmann machine (DBM), is an expressive family of machine learning models which can serve as compact representations of complex probability distributions.…

Machine Learning · Computer Science 2021-02-18 Haik Manukian , Massimiliano Di Ventra

Deep neural networks enjoy a powerful representation and have proven effective in a number of applications. However, recent advances show that deep neural networks are vulnerable to adversarial attacks incurred by the so-called adversarial…

Machine Learning · Computer Science 2019-11-21 Lirong He , Ziyi Guo , Kaizhu Huang , Zenglin Xu

A method to control results of gradient descent unsupervised learning in a deep neural network by using evolutionary algorithm is proposed. To process crossover of unsupervisedly trained models, the algorithm evaluates pointwise fitness of…

Machine Learning · Statistics 2018-03-29 Takeshi Inagaki

Accurate localization of proteins from fluorescence microscopy images is challenging due to the inter-class similarities and intra-class disparities introducing grave concerns in addressing multi-class classification problems. Conventional…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Muhammad Tahir , Saeed Anwar , Ajmal Mian , Abdul Wahab Muzaffar

Deep-predictive-coding networks (DPCNs) are hierarchical, generative models. They rely on feed-forward and feed-back connections to modulate latent feature representations of stimuli in a dynamic and context-sensitive manner. A crucial…

Artificial Intelligence · Computer Science 2021-09-27 Isaac J. Sledge , Jose C. Principe

In this paper we introduce the DMR -- a prototype-based method and network architecture for deep learning which is using a decision tree (DT)-based inference and synthetic data to balance the classes. It builds upon the recently introduced…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Plamen Angelov , Eduardo Soares

As high-throughput biological sequencing becomes faster and cheaper, the need to extract useful information from sequencing becomes ever more paramount, often limited by low-throughput experimental characterizations. For proteins, accurate…

Quantitative Methods · Quantitative Biology 2017-01-31 Xueliang Liu

Click-Through Rate prediction (CTR) is a crucial task in recommender systems, and it gained considerable attention in the past few years. The primary purpose of recent research emphasizes obtaining meaningful and powerful representations…

Information Retrieval · Computer Science 2022-10-26 Shereen Elsayed , Lars Schmidt-Thieme

The recent success in implementing supervised learning to classify modulation types suggests that other problems akin to modulation classification would eventually benefit from that implementation. One of these problems is classifying the…

Signal Processing · Electrical Eng. & Systems 2020-04-08 Jianyuan Yu , Mohammad Alhassoun , R. Michael Buehrer

Support vector machine (SVM) based multivariate pattern analysis (MVPA) has delivered promising performance in decoding specific task states based on functional magnetic resonance imaging (fMRI) of the human brain. Conventionally, the…

The lack of well-structured metadata annotations complicates there-usability and interpretation of the growing amount of publicly available RNA expression data. The machine learning-based prediction of metadata(data augmentation) can…

Machine Learning · Computer Science 2019-09-27 Jelena Fiosina , Maksims Fiosins , Stefan Bonn

This paper presents Discriminative Part Network (DP-Net), a deep architecture with strong interpretation capabilities, which exploits a pretrained Convolutional Neural Network (CNN) combined with a part-based recognition module. This system…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Ronan Sicre , Hanwei Zhang , Julien Dejasmin , Chiheb Daaloul , Stéphane Ayache , Thierry Artières

The brain is likely the most complex organ, given the variety of functions it controls, the number of cells it comprises, and their corresponding diversity. Studying and identifying neurons, the brain's primary building blocks, is a crucial…

Machine Learning · Computer Science 2023-06-02 Ofek Ophir , Orit Shefi , Ofir Lindenbaum