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The Deep Material Network (DMN) has emerged as a powerful framework for multiscale materials modeling, enabling efficient and accurate prediction of material behavior across different length scales. Unlike conventional data-driven…

Computational Engineering, Finance, and Science · Computer Science 2026-03-23 Ting-Ju Wei , Wen-Ning Wan , Chuin-Shan Chen

The functions of proteins and RNAs are determined by a myriad of interactions between their constituent residues, but most quantitative models of how molecular phenotype depends on genotype must approximate this by simple additive effects.…

Quantitative Methods · Quantitative Biology 2017-12-19 Adam J. Riesselman , John B. Ingraham , Debora S. Marks

Biological foundation models (BioFMs), pretrained on large-scale biological sequences, have recently shown strong potential in providing meaningful representations for diverse downstream bioinformatics tasks. However, such models often rely…

Machine Learning · Computer Science 2026-02-10 Yifan Wu , Jiyue Jiang , Xichen Ye , Yiqi Wang , Chang Zhou , Yitao Xu , Jiayang Chen , He Hu , Weizhong Zhang , Cheng Jin , Jiao Yuan , Yu Li

Deep neural networks (DNNs) achieve state-of-the-art results in a variety of domains. Unfortunately, DNNs are notorious for their non-interpretability, and thus limit their applicability in hypothesis-driven domains such as biology and…

Machine Learning · Computer Science 2018-03-12 Chun-Hao Chang , Ladislav Rampasek , Anna Goldenberg

While deep neural networks (DNN) have become an effective computational tool, the prediction results are often criticized by the lack of interpretability, which is essential in many real-world applications such as health informatics.…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Mengnan Du , Ninghao Liu , Qingquan Song , Xia Hu

Deep neural networks (DNNs) are vulnerable to adversarial examples and other data perturbations. Especially in safety critical applications of DNNs, it is therefore crucial to detect misclassified samples. The current state-of-the-art…

Machine Learning · Computer Science 2020-04-21 Julia Lust , Alexandru Paul Condurache

Deep neural networks (DNNs) offer significant flexibility and robust performance. This makes them ideal for building not only system models but also advanced neural network controllers (NNCs). However, their high complexity and…

Machine Learning · Computer Science 2025-11-14 Ganesh Sundaram , Jonas Ulmen , Amjad Haider , Daniel Görges

Despite a lack of theoretical understanding, deep neural networks have achieved unparalleled performance in a wide range of applications. On the other hand, shallow representation learning with component analysis is associated with rich…

Machine Learning · Computer Science 2018-03-20 Calvin Murdock , Ming-Fang Chang , Simon Lucey

Monitoring agricultural activities is important to ensure food security. Remote sensing plays a significant role for large-scale continuous monitoring of cultivation activities. Time series remote sensing data were used for the generation…

Machine Learning · Computer Science 2024-11-20 Kazi Hasibul Kabir , Md. Zahiruddin Aqib , Sharmin Sultana , Shamim Akhter

Based on the BioBricks standard, restriction synthesis is a novel catabolic iterative DNA synthesis method that utilizes endonucleases to synthesize a query sequence from a reference sequence. In this work, the reference sequence is built…

Signal Processing · Electrical Eng. & Systems 2020-12-14 Ethan J. Moyer , Anup Das

Inspired by a growing interest in analyzing network data, we study the problem of node classification on graphs, focusing on approaches based on kernel machines. Conventionally, kernel machines are linear classifiers in the implicit feature…

Machine Learning · Statistics 2010-01-25 Xiao Tang , Mu Zhu

Understanding the morphological changes of primary neuronal cells induced by chemical compounds is essential for drug discovery. Using the data from a single high-throughput imaging assay, a classification model for predicting the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-02 Andrey Kormilitzin , Xinyu Yang , William H. Stone , Caroline Woffindale , Francesca Nicholls , Elena Ribe , Alejo Nevado-Holgado , Noel Buckley

A new musical instrument classification method using convolutional neural networks (CNNs) is presented in this paper. Unlike the traditional methods, we investigated a scheme for classifying musical instruments using the learned features…

Sound · Computer Science 2015-12-24 Taejin Park , Taejin Lee

Deep neural networks (DNN) have achieved remarkable success in various fields, including computer vision and natural language processing. However, training an effective DNN model still poses challenges. This paper aims to propose a method…

Machine Learning · Computer Science 2024-07-03 Hejie Ying , Mengmeng Song , Yaohong Tang , Shungen Xiao , Zimin Xiao

In this paper, we applied a novel learning algorithm, namely, Deep Belief Networks (DBN) to word sense disambiguation (WSD). DBN is a probabilistic generative model composed of multiple layers of hidden units. DBN uses Restricted Boltzmann…

Computation and Language · Computer Science 2012-07-03 Peratham Wiriyathammabhum , Boonserm Kijsirikul , Hiroya Takamura , Manabu Okumura

Deep learning builds deep architectures such as multi-layered artificial neural networks to effectively represent multiple features of input patterns. The adaptive structural learning method of Deep Belief Network (DBN) can realize a high…

Neural and Evolutionary Computing · Computer Science 2019-10-01 Shin Kamada , Takumi Ichimura

Discriminative linear models are a popular tool in machine learning. These can be generally divided into two types: The first is linear classifiers, such as support vector machines, which are well studied and provide state-of-the-art…

Machine Learning · Computer Science 2012-07-02 Koby Crammer , Amir Globerson

Neural networks are the cornerstone of modern machine learning, yet can be difficult to interpret, give overconfident predictions and are vulnerable to adversarial attacks. Bayesian neural networks (BNNs) provide some alleviation of these…

Machine Learning · Statistics 2026-02-24 August Arnstad , Leiv Rønneberg , Geir Storvik

The Deep Boltzmann Machines (DBM) is a state-of-the-art unsupervised learning model, which has been successfully applied to handwritten digit recognition and, as well as object recognition. However, the DBM is limited in scene recognition…

Computer Vision and Pattern Recognition · Computer Science 2015-06-25 Jinfu Yang , Jingyu Gao , Guanghui Wang , Shanshan Zhang

We present a deep transformation model for probabilistic regression. Deep learning is known for outstandingly accurate predictions on complex data but in regression tasks, it is predominantly used to just predict a single number. This…

Machine Learning · Statistics 2020-04-02 Beate Sick , Torsten Hothorn , Oliver Dürr
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