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Visual short-term memory binding tasks are a promising early marker for Alzheimer's disease (AD). To uncover functional deficits of AD in these tasks it is meaningful to first study unimpaired brain function. Electroencephalogram recordings…

The influence of sex and age on cerebral perfusion is recognized, but the specific impacts on regional cerebral blood flow (CBF) and vascular risk remain to be fully characterized. In this study, 3D pseudo-continuous arterial spin labeling…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Sneha Noble , Neelam Sinha , Vaanathi Sundareshan , Thomas Gregor Issac

The auditory pathway is widely distributed throughout the brain, and is perhaps one of the most interesting networks in the context of neuroplasticity. Accurate mapping of neural activity in the entire pathway, preferably noninvasively, and…

Medical Physics · Physics 2019-03-21 Guilherme Blazquez Freches , Cristina Chavarrias , Noam Shemesh

Large efforts are currently under way to systematically map functional connectivity between all pairs of millimeter-scale brain regions using big volumes of neuroimaging data. Functional magnetic resonance imaging (fMRI) can produce these…

Neurons and Cognition · Quantitative Biology 2014-09-24 Enzo Tagliazucchi , Helmut Laufs , Dante R. Chialvo

This paper indicates causality as the tool that unifies the analysis of both activations and connectivity of brain areas, obtained with fMRI data. Causality analysis is commonly applied to study connectivity, so this work focuses on…

Methodology · Statistics 2011-02-25 Nevio Dubbini

Functional connectivity is a key approach to investigate oscillatory activities of the brain that provides important insights on the underlying dynamic of neuronal interactions and that is mostly applied for brain activity analysis.…

Neurons and Cognition · Quantitative Biology 2022-02-17 Marie-Constance Corsi , Sylvain Chevallier , Fabrizio De Vico Fallani , Florian Yger

To explain individual differences in development, behavior, and cognition, most previous studies focused on projecting resting-state functional MRI (fMRI) based functional connectivity (FC) data into a low-dimensional space via linear…

Neurons and Cognition · Quantitative Biology 2018-11-01 Li Xiao , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

In this study, we propose a neural network approach to capture the functional connectivities among anatomic brain regions. The suggested approach estimates a set of brain networks, each of which represents the connectivity patterns of a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Baran Baris Kivilcim , Itir Onal Ertugrul , Fatos T. Yarman Vural

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

Neurons and Cognition · Quantitative Biology 2017-12-22 Ravi Tejwani , Adam Liska , Hongyuan You , Jenna Reinen , Payel Das

Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization…

Neurons and Cognition · Quantitative Biology 2025-02-13 Xinglin Zeng , Yiran Li , Lin Hua , Ruoxi Lu , Lucas Lemos Franco , Peter Kochunov , Shuo Chen , John A Detre , Ze Wang

Transcriptomics, regional cerebral blood flow (rCBF), and a spatial motor virtual reality task were integrated using mediation analysis in a novel demonstration of "imaging omics". Data collected in NCAA Division I football athletes cleared…

Distributed networks of brain areas interact with one another in a time-varying fashion to enable complex cognitive and sensorimotor functions. Here we use novel network analysis algorithms to test the recruitment and integration of…

Neurons and Cognition · Quantitative Biology 2014-03-25 Danielle S. Bassett , Muzhi Yang , Nicholas F. Wymbs , Scott T. Grafton

Malnutrition is a main public health problem in developing countries. Incidence is increasing and the mortality rate is still high. Malnutrition can leads mayor problems that can be irreversible if it is present before brain development is…

Neurons and Cognition · Quantitative Biology 2013-01-21 R. Martin , R. Godinez , A. O. Rodriguez

Brain function relies on a precisely coordinated and dynamic balance between the functional integration and segregation of distinct neural systems. Characterizing the way in which neural systems reconfigure their interactions to give rise…

Neurons and Cognition · Quantitative Biology 2021-01-28 Lingbin Bian , Tiangang Cui , B. T. Thomas Yeo , Alex Fornito , Adeel Razi , Jonathan Keith

Functional magnetic resonance imaging (fMRI) is widely used in clinical applications to highlight brain areas involved in specific cognitive processes. Brain impairments, such as tumors, suppress the fMRI activation of the anatomical areas…

Neurons and Cognition · Quantitative Biology 2019-06-20 Qiongge Li , Gino Del Ferraro , Luca Pasquini , Kyung K. Peck , Hernan A. Makse , Andrei I. Holodny

Transcranial focused ultrasound (tFUS) is an emerging form of non-surgical human neuromodulation that confers advantages over existing electro and electromagnetic technologies by providing a superior spatial resolution on the millimeter…

Neurons and Cognition · Quantitative Biology 2016-03-02 Leo Ai , Jerel K. Mueller , Andrea Grant , Yigitcan Eryaman , Wynn Legon

Neuroimaging studies of psychiatric disorders often correlate imaging patterns with diagnostic labels or composite symptom scores, yielding diffuse associations that obscure underlying mechanisms. We instead seek to identify root-causal…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Eric V. Strobl

Cognitive flexibility describes the human ability to switch between modes of mental function to achieve goals. Mental switching is accompanied by transient changes in brain activity, which must occur atop an anatomical architecture that…

Neurons and Cognition · Quantitative Biology 2016-11-29 John D. Medaglia , Weiyu Huang , Elisabeth A. Karuza , Sharon L. Thompson-Schill , Alejandro Ribeiro , Danielle S. Bassett

Functional connectivity (FC) derived from resting-state fMRI plays a critical role in personalized predictions such as age and cognitive performance. However, applying foundation models(FM) to fMRI data remains challenging due to its high…

Neurons and Cognition · Quantitative Biology 2025-08-26 Yanwen Wang , Xinglin Zhao , Yijin Song , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen
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