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The Kimura 3-parameter model is one of the most fundamental phylogenetic models in algebraic statistics. We prove that all algebraic varieties associated to this model are projectively normal, confirming a conjecture of Michalek.

Algebraic Geometry · Mathematics 2019-03-01 Martin Vodička

The Kimura 3-parameter model on a tree of n leaves is one of the most used in phylogenetics. The affine algebraic variety W associated to it is a toric variety. We study its geometry and we prove that it is isomorphic to a geometric…

Algebraic Geometry · Mathematics 2007-05-23 Marta Casanellas , Jesus Fernandez-Sanchez

Identifiability of phylogenetic models is a necessary condition to ensure that the model parameters can be uniquely determined from data. Mixture models are phylogenetic models where the probability distributions in the model are convex…

Populations and Evolution · Quantitative Biology 2025-08-11 Bryson Kagy , Seth Sullivant

Group-based models arise in algebraic statistics while studying evolution processes. They are represented by embedded toric algebraic varieties. Both from the theoretical and applied point of view one is interested in determining the ideals…

Algebraic Geometry · Mathematics 2013-10-25 Mateusz Michalek

A phylogenetic variety is an algebraic variety parameterized by a statistical model of the evolution of biological sequences along a tree. Understanding this variety is an important problem in the area of algebraic statistics with…

Populations and Evolution · Quantitative Biology 2024-05-22 Luis David Garcia Puente , Marina Garrote-López , Elima Shehu

We study phylogenetic invariants of models of evolution whose group of symmetries is the cyclic group with 3 elements. We prove that projective schemes corresponding to the ideal I of phylogenetic invariants of such a model and to its…

Algebraic Geometry · Mathematics 2015-09-30 Maria Donten-Bury

In this paper we investigate properties of algebraic varieties representing group-based phylogenetic models. We propose a method of generating many phylogenetic invariants. We prove that we obtain all invariants for any tree for the binary…

Algebraic Geometry · Mathematics 2012-07-30 Maria Donten-Bury , Mateusz Michalek

By fixing all parameters in a phylogenetic likelihood model except for one branch length, one obtains a one-dimensional likelihood function. In this work, we introduce a mathematical framework to characterize the shapes of such…

Populations and Evolution · Quantitative Biology 2016-07-25 Vu Dinh , Frederick A. Matsen

The general Markov model of the evolution of biological sequences along a tree leads to a parameterization of an algebraic variety. Understanding this variety and the polynomials, called phylogenetic invariants, which vanish on it, is a…

Algebraic Geometry · Mathematics 2007-06-13 Elizabeth S. Allman , John A. Rhodes

Identifiability is a crucial property for a statistical model since distributions in the model uniquely determine the parameters that produce them. In phylogenetics, the identifiability of the tree parameter is of particular interest since…

Combinatorics · Mathematics 2019-10-01 Benjamin Hollering , Seth Sullivant

Motivated by phylogenetics, our aim is to obtain a system of equations that define a phylogenetic variety on an open set containing the biologically meaningful points. In this paper we consider phylogenetic varieties defined via group-based…

Algebraic Geometry · Mathematics 2014-02-28 Marta Casanellas , Jesús Fernández-Sánchez , Mateusz Michałek

Phylogenetic networks can represent evolutionary events that cannot be described by phylogenetic trees. These networks are able to incorporate reticulate evolutionary events such as hybridization, introgression, and lateral gene transfer.…

Populations and Evolution · Quantitative Biology 2021-07-08 Elizabeth Gross , Leo van Iersel , Remie Janssen , Mark Jones , Colby Long , Yukihiro Murakami

In most stochastic models of molecular sequence evolution the probability of each possible pattern of homologous characters at a site is estimated numerically. However in the case of Kimura's three-substitution-types (K3ST) model, these…

Populations and Evolution · Quantitative Biology 2007-05-23 Michael D. Hendy , Sagi Snir

An analysis of the Kimura 3ST model of DNA sequence evolution is given on the basis of its continuous Lie symmetries. The rate matrix commutes with a U(1)xU(1)xU(1) phase subgroup of the group GL(4) of 4x4x4 invertible complex matrices…

Populations and Evolution · Quantitative Biology 2013-07-23 J. D. Bashford , P. D. Jarvis , J. G. Sumner , M. A. Steel

We consider three classical models of biological evolution: (i) the Moran process, an example of a reducible Markov Chain; (ii) the Kimura Equation, a particular case of a degenerated Fokker-Planck Diffusion; (iii) the Replicator Equation,…

Populations and Evolution · Quantitative Biology 2020-10-09 Fabio A. C. C. Chalub , Léonard Monsaingeon , Ana Margarida Ribeiro , Max O. Souza

We introduce new methods for phylogenetic tree quartet construction by using machine learning to optimize the power of phylogenetic invariants. Phylogenetic invariants are polynomials in the joint probabilities which vanish under a model of…

Populations and Evolution · Quantitative Biology 2007-05-23 Nicholas Eriksson , Yuan Yao

We prove identifiability of the tree parameters of the 3-class Jukes-Cantor mixture model. The proof uses ideas from algebraic statistics, in particular: finding phylogenetic invariants that separate the varieties associated to different…

Populations and Evolution · Quantitative Biology 2014-08-12 Colby Long , Seth Sullivant

Buczy\'{n}ska and Wi\'{s}niewski showed that for the Jukes Cantor binary model of a 3-valent tree the Hilbert polynomial depends only on the number of leaves of the tree and not on its shape. We ask if this can be generalized to other…

Commutative Algebra · Mathematics 2010-07-20 Kaie Kubjas

Phylogenetic networks describe the evolution of a set of taxa for which reticulate events have occurred at some point in their evolutionary history. Of particular interest is when the evolutionary history between a set of just three taxa…

Populations and Evolution · Quantitative Biology 2024-09-27 Shelby Cox , Elizabeth Gross , Samuel Martin

The paper is devoted to the study of finite dimensional complex evolution algebras. The class of evolution algebras isomorphic to evolution algebras with Jordan form matrices is described. For finite dimensional complex evolution algebras…

Commutative Algebra · Mathematics 2018-05-01 L. M. Camacho , J. R. Gómez , B. A. Omirov , R. M. Turdibaev
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