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Researchers have long tried to minimize training costs in deep learning while maintaining strong generalization across diverse datasets. Emerging research on dataset distillation aims to reduce training costs by creating a small synthetic…
We consider the problem of clustering nested or hierarchical data, where observations are grouped and there are both group-level and observation-level variables. In our motivating OneK1K dataset, observations consist of single-cell…
RNA sequencing (RNA-seq) has been rapidly adopted for the profiling of transcriptomes in many areas of biology, including studies into gene regulation, development and disease. Of particular interest is the discovery of differentially…
Change point detection has become an important part of the analysis of the single-particle tracking data, as it allows one to identify moments, in which the motion patterns of observed particles undergo significant changes. The segmentation…
Genes are often regulated in living cells by proteins called transcription factors (TFs) that bind directly to short segments of DNA in close proximity to specific genes. These binding sites have a conserved nucleotide appearance, which is…
Single-cell RNA sequencing (scRNA-seq) and spatially-resolved imaging/sequencing technologies have revolutionized biomedical research. On one hand, scRNA-seq provides information about a large portion of the transcriptome for individual…
We introduce EM-Network, a novel self-distillation approach that effectively leverages target information for supervised sequence-to-sequence (seq2seq) learning. In contrast to conventional methods, it is trained with oracle guidance, which…
Background: Single-cell RNA sequencing (scRNA-seq) yields valuable insights about gene expression and gives critical information about complex tissue cellular composition. In the analysis of single-cell RNA sequencing, the annotations of…
Spatial transcriptomics (ST) is an emerging technology that enables researchers to investigate the molecular relationships underlying tissue morphology. However, acquiring ST data remains prohibitively expensive, and traditional fixed-grid…
Dataset distillation (DD) aims to generate a compact yet informative dataset that achieves performance comparable to the original dataset, thereby reducing demands on storage and computational resources. Although diffusion models have made…
Dataset distillation (DD) has witnessed significant progress in creating small datasets that encapsulate rich information from large original ones. Particularly, methods based on generative priors show promising performance, while…
Due to 5G millimeter wave (mmWave), spatial channel parameters are becoming highly resolvable, enabling accurate vehicle localization and mapping. We propose a novel method of radio simultaneous localization and mapping (SLAM) with the…
Conversational Search (CS) involves retrieving relevant documents from a corpus while considering the conversational context, integrating retrieval with context modeling. Recent advancements in Large Language Models (LLMs) have…
Speculative decoding (SD) accelerates large language model inference by employing a faster draft model for generating multiple tokens, which are then verified in parallel by the larger target model, resulting in the text generated according…
Distilled diffusion models generate images in far fewer timesteps but suffer from reduced sample diversity when generating multiple outputs from the same prompt. To understand this phenomenon, we first investigate whether distillation…
In causal inference with observational studies, synthetic control (SC) has emerged as a prominent tool. SC has traditionally been applied to aggregate-level datasets, but more recent work has extended its use to individual-level data. As…
Distance-based clustering and classification are widely used in various fields to group mixed numeric and categorical data. In many algorithms, a predefined distance measurement is used to cluster data points based on their dissimilarity.…
One of the major challenges arising from single-cell transcriptomics experiments is the question of how to annotate the associated single-cell transcriptomic profiles. Because of the large size and the high dimensionality of the data,…
The Bayesian approach to inference stands out for naturally allowing borrowing information across heterogeneous populations, with different samples possibly sharing the same distribution. A popular Bayesian nonparametric model for…
We consider the problem of clustering grouped data for which the observations may include group-specific variables in addition to the variables that are shared across groups. This type of data is common in cancer genomics where the…