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Most dataset distillation methods struggle to accommodate large-scale datasets due to their substantial computational and memory requirements. Recent research has begun to explore scalable disentanglement methods. However, there are still…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Zhiheng Ma , Anjia Cao , Funing Yang , Yihong Gong , Xing Wei

Single-cell RNA-Sequencing (scRNA-Seq) has undergone major technological advances in recent years, enabling the conception of various organism-level cell atlassing projects. With increasing numbers of datasets being deposited in public…

A central goal in systems biology and drug discovery is to predict the transcriptional response of cells to perturbations. This task is challenging due to the noisy and sparse nature of single-cell measurements, as well as the fact that…

Quantitative Methods · Quantitative Biology 2026-02-10 Chenglei Yu , Chuanrui Wang , Bangyan Liao , Tailin Wu

Single-molecule spectroscopy (SMS) is an exceptionally sensitive technique, but its inherently limited photon budget produces noisy data that can readily lead to subjective analyses, fitting errors, and reduced statistical power, obscuring…

Biological Physics · Physics 2026-03-19 Michael Lovemore , Joshua Botha , Bertus van Heerden , Tjaart Kruger

The iterative sampling procedure employed by diffusion models (DMs) often leads to significant inference latency. To address this, we propose Stochastic Consistency Distillation (SCott) to enable accelerated text-to-image generation, where…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Hongjian Liu , Qingsong Xie , TianXiang Ye , Zhijie Deng , Chen Chen , Shixiang Tang , Xueyang Fu , Haonan Lu , Zheng-jun Zha

Dataset distillation or condensation aims to generate a smaller but representative subset from a large dataset, which allows a model to be trained more efficiently, meanwhile evaluating on the original testing data distribution to achieve…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Zeyuan Yin , Zhiqiang Shen

Dataset distillation aims to find a synthetic training set such that training on the synthetic data achieves similar performance to training on real data, with orders of magnitude less computational requirements. Existing methods can be…

Machine Learning · Computer Science 2026-02-09 Hong Ye Tan , Emma Slade

Dataset distillation enables the training of deep neural networks with comparable performance in significantly reduced time by compressing large datasets into small and representative ones. Although the introduction of generative models has…

Machine Learning · Computer Science 2025-05-27 Mingzhuo Li , Guang Li , Jiafeng Mao , Takahiro Ogawa , Miki Haseyama

The data mining technique of time series clustering is well established in many fields. However, as an unsupervised learning method, it requires making choices that are nontrivially influenced by the nature of the data involved. The aim of…

Econometrics · Economics 2018-07-19 Iwo Augustyński , Paweł Laskoś-Grabowski

Despite their strong performances on many generative tasks, diffusion models require a large number of sampling steps in order to generate realistic samples. This has motivated the community to develop effective methods to distill…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Weijian Luo , Zemin Huang , Zhengyang Geng , J. Zico Kolter , Guo-jun Qi

Important tasks in the study of genomic data include the identification of groups of similar cells (for example by clustering), and visualisation of data summaries (for example by dimensional reduction). In this paper, we develop a novel…

Methodology · Statistics 2024-10-15 Thomas E. Bartlett , Swati Chandna , Sandipan Roy

In recent years, functional genomics approaches combining genetic information with bulk RNA-sequencing data have identified the downstream expression effects of disease-associated genetic risk factors through so-called expression…

Ensembles of machine learning models yield improved system performance as well as robust and interpretable uncertainty estimates; however, their inference costs may often be prohibitively high. \emph{Ensemble Distribution Distillation} is…

Machine Learning · Computer Science 2021-05-17 Max Ryabinin , Andrey Malinin , Mark Gales

Dataset distillation methods have achieved remarkable success in distilling a large dataset into a small set of representative samples. However, they are not designed to produce a distilled dataset that can be effectively used for…

Machine Learning · Computer Science 2024-04-15 Dong Bok Lee , Seanie Lee , Joonho Ko , Kenji Kawaguchi , Juho Lee , Sung Ju Hwang

Kernel-based subspace clustering, which addresses the nonlinear structures in data, is an evolving area of research. Despite noteworthy progressions, prevailing methodologies predominantly grapple with limitations relating to (i) the…

Machine Learning · Computer Science 2025-01-22 Kunpeng Xu , Lifei Chen , Shengrui Wang

Recent diffusion distillation methods have achieved remarkable progress, enabling high-quality ${\sim}4$-step sampling for large-scale text-conditional image and video diffusion models. However, further reducing the number of sampling steps…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Nikita Starodubcev , Ilya Drobyshevskiy , Denis Kuznedelev , Artem Babenko , Dmitry Baranchuk

Understanding the dynamic nature of biological systems is fundamental to deciphering cellular behavior, developmental processes, and disease progression. Single-cell RNA sequencing (scRNA-seq) has provided static snapshots of gene…

Quantitative Methods · Quantitative Biology 2025-05-02 Zhenyi Zhang , Yuhao Sun , Qiangwei Peng , Tiejun Li , Peijie Zhou

Recent advances in high-resolution sequencing have paved the way for population-scale analysis in single-cell RNA-sequencing (scRNA-seq) data. scRNA-seq data, in particular, have proven to be extremely powerful in profiling a variety of…

Methodology · Statistics 2025-10-30 Hanxuan Ye , Zachary Qian , Hongzhe Li

Dataset distillation (DD) has emerged as a widely adopted technique for crafting a synthetic dataset that captures the essential information of a training dataset, facilitating the training of accurate neural models. Its applications span…

Machine Learning · Computer Science 2025-02-04 Saeed Vahidian , Mingyu Wang , Jianyang Gu , Vyacheslav Kungurtsev , Wei Jiang , Yiran Chen

We address the problem of retrieving relevant experiments given a query experiment, motivated by the public databases of datasets in molecular biology and other experimental sciences, and the need of scientists to relate to earlier work on…

Machine Learning · Statistics 2014-03-10 Ritabrata Dutta , Sohan Seth , Samuel Kaski