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Parameter inference for stochastic differential equation mixed effects models (SDEMEMs) is a challenging problem. Analytical solutions for these models are rarely available, which means that the likelihood is also intractable. In this case,…

Computation · Statistics 2019-09-30 Imke Botha , Robert Kohn , Christopher Drovandi

This paper studies the remote state estimation problem of linear time-invariant systems with stochastic event-triggered sensor schedules in the presence of packet drops between the sensor and the estimator. It is shown that the system state…

Optimization and Control · Mathematics 2019-04-04 Liang Xu , Yilin Mo , Lihua Xie

Computing the conditional mode of a distribution, better known as the $\mathit{maximum\ a\ posteriori}$ (MAP) assignment, is a fundamental task in probabilistic inference. However, MAP estimation is generally intractable, and remains hard…

Machine Learning · Computer Science 2026-01-23 Matthew Shorvon , Frederik Mallmann-Trenn , David S. Watson

Ordinary differential equations (ODE) are widely used for modeling in Systems Biology. As most commonly only some of the kinetic parameters are measurable or precisely known, parameter estimation techniques are applied to parametrize the…

Quantitative Methods · Quantitative Biology 2016-01-19 Christoph Zimmer , Frank T. Bergmann , Sven Sahle

We introduce a lattice random walk discretisation scheme for stochastic differential equations (SDEs) that samples binary or ternary increments at each step, suppressing complex drift and diffusion computations to simple 1 or 2 bit random…

Numerical Analysis · Mathematics 2026-02-18 Samuel Duffield , Maxwell Aifer , Denis Melanson , Zach Belateche , Patrick J. Coles

Sparse autoencoders (SAEs) have received considerable recent attention as tools for mechanistic interpretability, showing success at extracting interpretable features even from very large LLMs. However, this research has been largely…

Machine Learning · Computer Science 2025-05-20 Jeremy Budd , Javier Ideami , Benjamin Macdowall Rynne , Keith Duggar , Randall Balestriero

In this paper is proposed a novel incremental iterative Gauss-Newton-Markov-Kalman filter method for state estimation of dynamic models given noisy measurements. The mathematical formulation of the proposed filter is based on the…

Optimization and Control · Mathematics 2019-09-17 Bojana Rosic

A recently developed measure-theoretic framework solves a stochastic inverse problem (SIP) for models where uncertainties in model output data are predominantly due to aleatoric (i.e., irreducible) uncertainties in model inputs (i.e.,…

Numerical Analysis · Mathematics 2023-02-15 Michael Pilosov , Carlos del-Castillo-Negrete , Tian Yu Yen , Troy Butler , Clint Dawson

Distribution System State Estimation (DSSE) is becoming increasingly important with the integration of Distributed Energy Resources (DERs) and the active operation of distribution networks (DNs), but it remains challenging due to the…

Optimization and Control · Mathematics 2026-05-25 J. G. De la Varga , S. Pineda , A. Stratigakos , J. M. Morales

We introduce a predictor-corrector discretisation scheme for the numerical integration of a class of stochastic differential equations and prove that it converges with weak order 1.0. The key feature of the new scheme is that it builds up…

Computation · Statistics 2024-02-01 Deniz Akyildiz , Dan Crisan , Joaquin Miguez

Estimating probabilistic deformable template models is a new approach in the fields of computer vision and probabilistic atlases in computational anatomy. A first coherent statistical framework modelling the variability as a hidden random…

Computation · Statistics 2009-01-16 Stéphanie Allassonnière , Estelle Kuhn

The likelihood functions for discretely observed nonlinear continuous-time models based on stochastic differential equations are not available except for a few cases. Various parameter estimation techniques have been proposed, each with…

Methodology · Statistics 2025-04-17 Predrag Pilipovic , Adeline Samson , Susanne Ditlevsen

We propose and analyze an a posteriori error estimator for a PDE-constrained optimization problem involving a nondifferentiable cost functional, fractional diffusion, and control-constraints. We realize fractional diffusion as the…

Numerical Analysis · Mathematics 2019-06-04 Enrique Otarola

Nonlinear (systems of) ordinary differential equations (ODEs) are common tools in the analysis of complex one-dimensional dynamic systems. In this paper we propose a smoothing approach regularized by a quasilinearized ODE-based penalty in…

Methodology · Statistics 2014-04-30 Gianluca Frasso , Jonathan Jaeger , Philippe Lambert

We construct a nonstandard finite difference numerical scheme to approximate stochastic differential equations (SDEs) using the idea of weighed step introduced by R.E. Mickens. We prove the strong convergence of our scheme under locally…

Numerical Analysis · Mathematics 2015-07-23 Frédéric Pierret

Overparameterized stochastic differential equation (SDE) models have achieved remarkable success in various complex environments, such as PDE-constrained optimization, stochastic control and reinforcement learning, financial engineering,…

Optimization and Control · Mathematics 2024-09-27 Shengbo Wang , Jose Blanchet , Peter Glynn

The data-driven discovery of interpretable models approximating the underlying dynamics of a physical system has gained attraction in the past decade. Current approaches employ pre-specified functional forms or basis functions and often…

Machine Learning · Computer Science 2025-07-30 Rahul Golder , M. M. Faruque Hasan

The Expectation Maximization (EM) algorithm is of key importance for inference in latent variable models including mixture of regressors and experts, missing observations. This paper introduces a novel EM algorithm, called…

Machine Learning · Computer Science 2020-12-04 Gersende Fort , Eric Moulines , Hoi-To Wai

We consider stochastic semi-linear evolution equations which are driven by additive, spatially correlated, Wiener noise, and in particular consider problems of heat equation (analytic semigroup) and damped-driven wave equations (bounded…

Probability · Mathematics 2016-07-13 Charles-Edouard Bréhier , Martin Hairer , Andrew M. Stuart

This paper introduces time-continuous numerical schemes to simulate stochastic differential equations (SDEs) arising in mathematical finance, population dynamics, chemical kinetics, epidemiology, biophysics, and polymeric fluids. These…

Probability · Mathematics 2015-03-13 Nawaf Bou-Rabee , Eric Vanden-Eijnden