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On the increase of major depressive disorders (MDD), many researchers paid attention to their recognition and treatment. Existing MDD recognition algorithms always use a single time-frequency domain method method, but the single…

Neurons and Cognition · Quantitative Biology 2021-11-03 Xiaofang Sun , Xiangwei Zheng , Yonghui Xu , Lizhen Cui , Bin Hu

Background: Depression has become a major health burden worldwide, and effective detection depression is a great public-health challenge. This Electroencephalography (EEG)-based research is to explore the effective biomarkers for depression…

Signal Processing · Electrical Eng. & Systems 2020-02-26 Shuting Sun , Jianxiu Li , Huayu Chen , Tao Gong , Xiaowei Li , Bin Hu

Major depressive disorder is a serious and heterogeneous psychiatric disorder that needs accurate diagnosis. Resting-state functional MRI (rsfMRI), which captures multiple perspectives on brain structure, function, and connectivity, is…

Machine Learning · Computer Science 2023-08-21 Yunsong Luo , Wenyu Chen , Ling Zhan , Jiang Qiu , Tao Jia

Diagnosis of major depressive disorder (MDD) primarily relies on the patient's self-reported symptoms and a clinical evaluation. Effective connectivity (EC) from resting-state functional magnetic resonance imaging (rs-fMRI) analysis can…

Neurons and Cognition · Quantitative Biology 2024-01-01 Peishan Dai , Yun Shi , Tong Xiong , Xiaoyan Zhou , Shenghui Liao , Zhongchao Huang , Xiaoping Yi , Bihong T. Chen

Functional magnetic resonance imaging recordings in the resting-state (RS) from the human brain are characterized by spontaneous low-frequency fluctuations in the blood oxygenation level dependent signal that reveal functional connectivity…

Neurons and Cognition · Quantitative Biology 2013-02-21 Iwo Jerzy Bohr , Eva Kenny , Andrew Blamire , John T. O'Brien , Alan J. Thomas , Jonathan Richardson , Marcus Kaiser

Major depressive disorder (MDD) is a complex psychiatric disorder that affects the lives of hundreds of millions of individuals around the globe. Even today, researchers debate if morphological alterations in the brain are linked to MDD,…

Quantitative Methods · Quantitative Biology 2025-01-27 Roberto Goya-Maldonado , Tracy Erwin-Grabner , Ling-Li Zeng , Christopher R. K. Ching , Andre Aleman , Alyssa R. Amod , Zeynep Basgoze , Francesco Benedetti , Bianca Besteher , Katharina Brosch , Robin Bülow , Romain Colle , Colm G. Connolly , Emmanuelle Corruble , Baptiste Couvy-Duchesne , Kathryn Cullen , Udo Dannlowski , Christopher G. Davey , Annemiek Dols , Jan Ernsting , Jennifer W. Evans , Lukas Fisch , Paola Fuentes-Claramonte , Ali Saffet Gonul , Ian H. Gotlib , Hans J. Grabe , Nynke A. Groenewold , Dominik Grotegerd , Tim Hahn , J. Paul Hamilton , Laura K. M. Han , Ben J. Harrison , Tiffany C. Ho , Neda Jahanshad , Alec J. Jamieson , Andriana Karuk , Tilo Kircher , Bonnie Klimes-Dougan , Sheri-Michelle Koopowitz , Thomas Lancaster , Ramona Leenings , Meng Li , David E. J. Linden , Frank P. MacMaster , David M. A. Mehler , Susanne Meinert , Elisa Melloni , Bryon A. Mueller , Benson Mwangi , Igor Nenadić , Amar Ojha , Yasumasa Okamoto , Mardien L. Oudega , Brenda W. J. H. Penninx , Sara Poletti , Edith Pomarol-Clotet , Maria J. Portella , Elena Pozzi , Joaquim Radua , Elena Rodríguez-Cano , Matthew D. Sacchet , Raymond Salvador , Anouk Schrantee , Kang Sim , Jair C. Soares , Aleix Solanes , Dan J. Stein , Frederike Stein , Aleks Stolicyn , Sophia I. Thomopoulos , Yara J. Toenders , Aslihan Uyar-Demir , Eduard Vieta , Yolanda Vives-Gilabert , Henry Völzke , Martin Walter , Heather C. Whalley , Sarah Whittle , Nils Winter , Katharina Wittfeld , Margaret J. Wright , Mon-Ju Wu , Tony T. Yang , Carlos Zarate , Dick J. Veltman , Lianne Schmaal , Paul M. Thompson

Clinical depression or Major Depressive Disorder (MDD) is a common and serious medical illness. In this paper, a deep recurrent neural network-based framework is presented to detect depression and to predict its severity level from speech.…

Human-Computer Interaction · Computer Science 2020-03-13 Emna Rejaibi , Ali Komaty , Fabrice Meriaudeau , Said Agrebi , Alice Othmani

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Emerging evidence showed that major depressive disorder (MDD) is associated with disruptions of brain structural and functional networks, rather than impairment of isolated brain region. Thus, connectome-based models capable of predicting…

Neurons and Cognition · Quantitative Biology 2021-10-18 Aya Kabbara , Gabriel Robert , Mohamad Khalil , Marc Verin , Pascal Benquet , Mahmoud Hassan

Recently, multimodal depression recognition for clinical interviews (MDRC) has recently attracted considerable attention. Existing MDRC studies mainly focus on improving task performance and have achieved significant development. However,…

Computation and Language · Computer Science 2025-01-28 Wenjie Zheng , Qiming Xie , Zengzhi Wang , Jianfei Yu , Rui Xia

Major depressive disorder (MDD) is one of the most common mental health conditions that has been intensively investigated for its association with brain atrophy and mortality. Recent studies reveal that the deviation between the predicted…

Neurons and Cognition · Quantitative Biology 2022-10-18 Yunsong Luo , Wenyu Chen , Jiang Qiu , Tao Jia

Functional connectivity (FC) has been widely used to study brain network interactions underlying the emerging cognition and behavior of an individual. FC is usually defined as the correlation or partial correlation between brain regions.…

Applications · Statistics 2020-10-27 Gemeng Zhang , Aiying Zhang , Biao Cai , Zhuozhuo Tu , Vince D. Calhoun , Yu-Ping Wang

Background: The treatment of depressive episodes is well established, with clearly demonstrated effectiveness of antidepressants and psychotherapies. However, more than one-third of depressed patients do not respond to treatment.…

Neurons and Cognition · Quantitative Biology 2024-03-29 Sébastien Dam , Jean-Marie Batail , Gabriel H Robert , Dominique Drapier , Pierre Maurel , Julie Coloigner

Machine learning (ML) techniques have gained popularity in the neuroimaging field due to their potential for classifying neuropsychiatric disorders. However, the diagnostic predictive power of the existing algorithms has been limited by…

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

Neurons and Cognition · Quantitative Biology 2017-12-22 Ravi Tejwani , Adam Liska , Hongyuan You , Jenna Reinen , Payel Das

Mild cognitive impairment (MCI) is a high-risk dementia condition which progresses to probable Alzheimer's disease (AD) at approximately 10% to 15% per year. Characterization of group-level differences between two subtypes of MCI - stable…

Neurons and Cognition · Quantitative Biology 2021-06-15 Lu Zhang , Xiaowei Yu , Yanjun Lyu , Li Wang , Dajiang Zhu

Depression, a prevalent and serious mental health issue, affects approximately 3.8\% of the global population. Despite the existence of effective treatments, over 75\% of individuals in low- and middle-income countries remain untreated,…

Computation and Language · Computer Science 2024-07-19 Shengjie Li , Yinhao Xiao

Depression has been a leading cause of mental-health illnesses across the world. While the loss of lives due to unmanaged depression is a subject of attention, so is the lack of diagnostic tests and subjectivity involved. Using behavioural…

Artificial Intelligence · Computer Science 2020-10-07 Shivani Shimpi , Shyam Thombre , Snehal Reddy , Ritik Sharma , Srijan Singh

Brain functional connectivity (FC) extracted from resting-state fMRI (RS-fMRI) has become a popular approach for disease diagnosis, where discriminating subjects with mild cognitive impairment (MCI) from normal controls (NC) is still one of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Weizheng Yan , Han Zhang , Jing Sui , Dinggang Shen

Data-driven approaches for depression diagnosis have emerged as a significant research focus in neuromedicine, driven by the development of relevant datasets. Recently, graph neural network (GNN)-based models have gained widespread adoption…

Machine Learning · Computer Science 2025-05-01 Chengkai Yang , Xingping Dong , Xiaofen Zong
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