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Collective and directed motility or swarming is an emergent phenomenon displayed by many self-organized assemblies of active biological matter such as clusters of embryonic cells during tissue development, cancerous cells during tumor…

Biological Physics · Physics 2016-04-05 Katherine Copenhagen , Ajay Gopinathan

Chemotactic interactions are ubiquitous in nature and can lead to nonreciprocal and complex emergent behavior in multibody systems. Here we show how chemotactic signaling between microscale oil droplets of different chemistries in micellar…

Bacteria can adjust their swimming behaviour in response to chemical variations, a phenomenon known as chemotaxis. This process is characterised by a drift velocity that depends non-linearly on the concentration of chemical species and its…

Fluid Dynamics · Physics 2026-05-07 Adam Gargasson , Julien Bouvard , Carine Douarche , Peter Mergaert , Harold Auradou

Chemotaxis receptors in E. coli form clusters at the cell poles and also laterally along the cell body, and this clustering plays an important role in signal transduction. Recently, experiments using flourrescence imaging have shown that,…

Statistical Mechanics · Physics 2008-11-29 Hui Wang , Ned S. Wingreen , Ranjan Mukhopadhyay

Personalized models of the gut microbiome are valuable for disease prevention and treatment. For this, one requires a mathematical model that predicts microbial community composition and the emergent behavior of microbial communities. We…

Populations and Evolution · Quantitative Biology 2019-10-29 James D. Brunner , Nicholas Chia

Many living and artificial systems show a similar emergent behavior and collective motions on different scales, starting from swarms of bacteria to synthetic active particles, herds of mammals and crowds of people. What all these systems…

Soft Condensed Matter · Physics 2024-01-01 Bohdan Senyuk , Jin-Sheng Wua , Ivan I. Smalyukh

Chemotaxis systems of Keller--Segel type constitute one of the central mathematical frameworks for understanding aggregation phenomena in biological and ecological systems. Over the past decades, the theory has evolved from the classical…

Analysis of PDEs · Mathematics 2026-03-06 Kolade M Owolabi , Eben Mare , Clara O Ijalana , Kolawole S Adegbie

Many processes in biology involve both reactions and chemotaxis. However, to the best of our knowledge, the question of interaction between chemotaxis and reactions has not yet been addressed either analytically or numerically. We consider…

Analysis of PDEs · Mathematics 2011-04-05 Alexander Kiselev , Lenya Ryzhik

This article is devoted to the mathematical modeling of migration of neuroblasts, precursor cells of neurons, along the pathway they usually follow before maturing. This pathway is determined mainly by chemotaxis and the heterogeneous…

Directed fibroblast migration is central to highly proliferative processes in regenerative medicine and developmental biology, such as wound healing and embryogenesis. However, the mechanisms by which single fibroblasts affect each other's…

Cell Behavior · Quantitative Biology 2018-08-29 Q. L. Pham , D. Chege , T. Dijamco , J. Brito , E. Stein , N. A. N. Tong , S. Basuray , R. S. Voronov

The bacterium E. coli maneuvers itself to regions with high chemoattractant concentrations by performing two stereotypical moves: `runs', in which it moves in near straight lines, and `tumbles', in which it does not advance but changes…

Cell Behavior · Quantitative Biology 2007-11-29 Yariv Kafri , Rava Azeredo da Silveira

Inspired by the chemotaxis interaction of living cells, we have developed an agent-based approach for self-organizing shape formation. Since all our simulations begin with a different uniform random configuration and our agents move…

Multiagent Systems · Computer Science 2018-03-13 Sean Grimes , Linge Bai , Andrew W. E. McDonald , David E. Breen

The existence of travelling waves for a model of concentration waves of bacteria is investigated. The model consists in a kinetic equation for the biased motion of cells following a run-and-tumble process, coupled with two…

Analysis of PDEs · Mathematics 2016-07-05 Vincent Calvez

In this paper we develop a field-theoretic description for run and tumble chemotaxis, based on a density functional description of crystalline materials modified to capture orientational ordering. We show that this framework, with its…

Soft Condensed Matter · Physics 2021-03-10 Purba Chatterjee , Nigel Goldenfeld

Phototaxis is an important reaction to light displayed by a wide range of motile microorganisms. Flagellated eukaryotic microalgae in particular, like the model organism Chlamydomonas reinhardtii, steer either towards or away from light by…

Cell Behavior · Quantitative Biology 2016-11-28 Jorge Arrieta , Ana Barreira , Maurizio Chioccioli , Marco Polin , Idan Tuval

Although tissues are usually studied in isolation, this situation rarely occurs in biology, as cells, tissues, and organs, coexist and interact across scales to determine both shape and function. Here, we take a quantitative approach…

Tissues and Organs · Quantitative Biology 2023-02-07 Carles Falcó , Daniel J. Cohen , José A. Carrillo , Ruth E. Baker

To understand the relationship between the chirality of individual cells and that of tissues and organisms, we have developed a chiral polarized particle model to investigate the movement of cell populations on substrates. Our model…

Biological Physics · Physics 2024-07-02 Xi Li , Bin Chen

A novel mechanism of reaction-induced active molecular motion, not involving any kind of self-propulsion, is proposed and analyzed. Because of the momentum exchange with the surrounding solvent, conformational transitions in…

Soft Condensed Matter · Physics 2023-04-19 Hiroyuki Kitahata , Alexander S. Mikhailov

Various microorganisms and some mammalian cells are able to swim in viscous fluids by performing nonreciprocal body deformations, such as rotating attached flagella or by distorting their entire body. In order to perform chemotaxis, i.e. to…

Biological Physics · Physics 2021-05-06 Benedikt Hartl , Maximilian Hübl , Gerhard Kahl , Andreas Zöttl

Mathematical and computational models can assist in gaining an understanding of cell behavior at many levels of organization. Here, we review models in the literature that focus on eukaryotic cell motility at 3 size scales: intracellular…

Cell Behavior · Quantitative Biology 2021-01-27 Andreas Buttenschön , Leah Edelstein-Keshet
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