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Thermal denaturation of DNA is often studied with coarse-grained models in which native sequential base pairing is mimicked by the existence of attractive interactions only between monomers at the same position along strands (Poland and…

Statistical Mechanics · Physics 2014-01-22 Jaya Maji , Somendra M. Bhattacharjee , Flavio Seno , Antonio Trovato

A three-stranded DNA with short range base pairings only is known to exhibit a classical analog of the quantum Efimov effect, viz., a three chain bound state at the two chain melting point where no two are bound. By using a non-perturbative…

Soft Condensed Matter · Physics 2015-04-13 Tanmoy Pal , Poulomi Sadhukhan , Somendra M. Bhattacharjee

We define a generalised model for three-stranded DNA consisting of two chains of one type and a third chain of a different type. The DNA strands are modelled by random walks on the three-dimensional cubic lattice with different interactions…

Statistical Mechanics · Physics 2021-08-25 Somendra M. Bhattacharjee , Damien Paul Foster

The base sequences of DNA contain the genetic code and to decode it a double helical DNA has to open its base pairs. Recent studies have shown that one can use a third strand to identify the base sequences without opening the double helix…

Soft Condensed Matter · Physics 2014-11-21 Jaya Maji , Somendra M. Bhattacharjee , Flavio Seno , Antonio Trovato

We study the melting of three-stranded DNA by using the real-space renormalization group and exact recursion relations. The prediction of an unusual Efimov-analog three-chain bound state, that appears at the critical melting of two-chain…

Statistical Mechanics · Physics 2012-10-30 Jaya Maji , Somendra M. Bhattacharjee

We show that there exists an Efimov-like three strand DNA bound state at the duplex melting point and it is described by a renormalization group limit cycle. A nonperturbative RG is used to obtain this result in a model involving short…

Soft Condensed Matter · Physics 2013-03-06 Tanmoy Pal , Poulomi Sadhukhan , Somendra M. Bhattacharjee

Systems of three particles show a surprising feature in their bound state spectrum: a series of geometrically scaled states, known as Efimov states. These states have not yet been observed directly, but many recent experiments show indirect…

Atomic Physics · Physics 2013-10-01 Peder K. Sørensen

The DNA molecule is modeled by a parabola embedded chain with long-range interactions between twisted base pair dipoles. A mechanism for bubble generation is presented and investigated in two different configurations. Using random normally…

Pattern Formation and Solitons · Physics 2007-05-23 Peter V. Larsen , Peter L. Christiansen , Ole Bang , Juan F. R. Archilla , Yuri B. Gaididei

The closure dynamics of a pre-equilibrated DNA denaturation bubble is studied using both Brownian dynamics simulations and an analytical approach. The numerical model consists of two semi-flexible interacting single strands (ssDNA) and a…

Soft Condensed Matter · Physics 2012-05-31 Anil Kumar Dasanna , Nicolas Destainville , John Palmeri , Manoel Manghi

For a system of three identical bosons interacting via short-range forces, when two of the atoms are about to form a two-body s-wave dimer, there exists an infinite number of three-body bound states. This effect is the well-known Efimov…

Atomic Physics · Physics 2015-06-11 Jia Wang , J. P. D'Incao , Yujun Wang , Chris H. Greene

The flexibility and the extension along the direction of the force are shown to be related to the bubble number fluctuation and the average number of bubbles respectively, when the strands of the DNA are subjected to a force along the same…

Soft Condensed Matter · Physics 2021-05-21 Debjyoti Majumdar

We determine the three-body bound states of an atom in a Fermi mixture. Compared to the Efimov spectrum of three atoms in vacuum, we show that the Fermi seas deform the Efimov spectrum systematically. We demonstrate that this effect is more…

Atomic Physics · Physics 2020-08-04 Ali Sanayei , Ludwig Mathey

The Efimov effect was first predicted for three particles interacting at an $s$-wave resonance in three dimensions. Subsequent study showed that the same effect can be realized by considering two-body and three-body interactions in mixed…

Quantum Gases · Physics 2017-09-27 Pengfei Zhang , Zhenhua Yu

The temperature dependence of DNA flexibility is studied in the presence of stretching and unzipping forces. Two classes of models are considered. In one case the origin of elasticity is entropic due to the polymeric correlations, and in…

Soft Condensed Matter · Physics 2016-06-27 Tanmoy Pal , Somendra M. Bhattacharjee

The closure of long equilibrated denaturation bubbles in DNA is studied using Brownian dynamics simulations. A minimal mesoscopic model is used where the double-helix is made of two interacting bead-spring freely rotating strands, with a…

Soft Condensed Matter · Physics 2015-06-12 Anil Kumar Dasanna , Nicolas Destainville , John Palmeri , Manoel Manghi

The formation of local denaturation zones (bubbles) in double-stranded DNA is an important example for conformational changes of biological macromolecules. We study the dynamics of bubble formation in terms of a Fokker-Planck equation for…

Soft Condensed Matter · Physics 2009-11-10 Andreas Hanke , Ralf Metzler

We discuss the thermodynamic behaviour near the force induced unzipping transition of a double stranded DNA in two different ensembles. The Y-fork is identified as the coexisting phases in the fixed distance ensemble. From finite size…

Soft Condensed Matter · Physics 2007-05-23 Rajeev Kapri , Somendra M. Bhattacharjee

The formation of bubbles in nucleic acids (NAs) are fundamental in many biological processes such as DNA replication, recombination, telomeres formation, nucleotide excision repair, as well as RNA transcription and splicing. These precesses…

Biomolecules · Quantitative Biology 2007-05-23 D. Hennig , J. F. R. Archilla , J. M. Romero

The issue of the nucleation and slow closure mechanisms of non superhelical stress-induced denaturation bubbles in DNA is tackled using coarse-grained MetaDynamics and Brownian simulations. A minimal mesoscopic model is used where the…

Soft Condensed Matter · Physics 2015-04-13 François Sicard , Nicolas Destainville , Manoel Manghi

The dynamical properties of double-stranded DNA are studied in the framework of the Peyrard-Bishop-Dauxois model using Langevin dynamics. Our simulations are analyzed in terms of two probability functions describing coherently localized…

Soft Condensed Matter · Physics 2007-06-13 B. S. Alexandrov , L. T. Wille , K. O. Rasmussen , A. R. Bishop , K. B. Blagoev
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