English

Melting behavior and different bound states in three-stranded DNA models

Statistical Mechanics 2014-01-22 v3 Soft Condensed Matter

Abstract

Thermal denaturation of DNA is often studied with coarse-grained models in which native sequential base pairing is mimicked by the existence of attractive interactions only between monomers at the same position along strands (Poland and Scheraga models). Within this framework, the existence of a three strand DNA bound state in conditions where a duplex DNA would be in the denaturated state was recently predicted from a study of three directed polymer models on simplified hierarchical lattices (d>2d>2) and in 1+11+1 dimensions. Such phenomenon which is similar to the Efimov effect in nuclear physics was named Efimov-DNA. In this paper we study the melting of the three-stranded DNA on a Sierpinski gasket of dimensions d<2d<2 by assigning extra weight factors to fork openings and closings, to induce a two-strand DNA melting. In such a context we can find again the existence of the Efimov-DNA-like state but quite surprisingly we discover also the presence of a different phase, to be called a mixed state, where the strands are pair-wise bound but without three chain contacts. Whereas the Efimov DNA turns out to be a crossover near melting, the mixed phase is a thermodynamic phase.

Keywords

Cite

@article{arxiv.1306.4206,
  title  = {Melting behavior and different bound states in three-stranded DNA models},
  author = {Jaya Maji and Somendra M. Bhattacharjee and Flavio Seno and Antonio Trovato},
  journal= {arXiv preprint arXiv:1306.4206},
  year   = {2014}
}

Comments

corrected file uploaded

R2 v1 2026-06-22T00:35:55.297Z