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We propose a novel inverse method that utilizes a set of data to construct a simple equation that governs the stochastic process for which the data have been measured, hence enabling us to reconstruct the stochastic process. As an example,…

Statistical Mechanics · Physics 2007-05-23 J. Peinke , M. Reza Rahimi Tabar , Muhammad Sahimi , F. Ghasemi

Recent developments in cardiovascular modelling allow us to simulate blood flow in an entire human body. Such model can also be used to create databases of virtual subjects, with sizes limited only by computational resources. In this work,…

Medical Physics · Physics 2020-07-01 Janne M. J. Huttunen , Leo Kärkkäinen , Harri Lindholm

Laboratory value represents a cornerstone of medical diagnostics, but suffers from slow turnaround times, and high costs and only provides information about a single point in time. The continuous estimation of laboratory values from…

Signal Processing · Electrical Eng. & Systems 2025-11-21 Juan Miguel Lopez Alcaraz , Nils Strodthoff

Electrocardiogram (ECG) is one of the most convenient and non-invasive tools for monitoring peoples' heart condition, which can use for diagnosing a wide range of heart diseases, including Cardiac Arrhythmia, Acute Coronary Syndrome, et al.…

Signal Processing · Electrical Eng. & Systems 2020-07-08 Shenda Hong , Zhaoji Fu , Rongbo Zhou , Jie Yu , Yongkui Li , Kai Wang , Guanlin Cheng

ECGSYN, a dynamical model that faithfully reproduces the main features of the human electrocardiogram (ECG), including heart rate variability, RR intervals and QT intervals is presented. Details of the underlying algorithm and an…

Medical Physics · Physics 2007-05-23 Patrick E. McSharry , Gari D. Cifford

A discrete time model that is capable of replicating the basic features of cardiac cell action potentials is suggested. The paper shows how the map-based approaches can be used to design highly efficient computational models (algorithms)…

Cell Behavior · Quantitative Biology 2007-08-10 Nikolai F. Rulkov

The approach of causality based on physical laws and systems is revisited. The issue of "levels", the relevance to epidemiology and the definition of effects are particularly developed. Moreover it is argued that this approach that we call…

Statistics Theory · Mathematics 2012-03-27 Daniel Commenges

Analyzing the cardiovascular system condition via Electrocardiography (ECG) is a common and highly effective approach, and it has been practiced and perfected over many decades. ECG sensing is non-invasive and relatively easy to acquire,…

Atrial Fibrillation is a heart condition characterized by erratic heart rhythms caused by chaotic propagation of electrical impulses in the atria, leading to numerous health complications. State-of-the-art models employ complex algorithms…

Quantitative Methods · Quantitative Biology 2019-12-02 Paul Samuel Ignacio , David Uminsky , Christopher Dunstan , Esteban Escobar , Luke Trujillo

The electrocardiogram (ECG) is a vital tool for diagnosing heart diseases. However, many disease patterns are derived from outdated datasets and traditional stepwise algorithms with limited accuracy. This study presents a method for direct…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Oğuzhan Büyüksolak , İlkay Öksüz

In this paper we will address the problem of developing mathematical models for the numerical simulation of the human circulatory system. In particular, we will focus our attention on the problem of haemodynamics in large human arteries.

Dynamical Systems · Mathematics 2007-05-23 Alfio Quarteroni

Background: How can mathematics help us to understand the mechanism of the cardiac motion? The best known approach is to take a mathematical model of the fibered structure, insert it into a more-or-less complex model of cardiac…

Medical Physics · Physics 2014-06-25 Saeed Ranjbar , Mersedeh Karvandi

We study the homogenization of a novel microscopic tridomain system, allowing for a more detailed analysis of the properties of cardiac conduction than the classical bidomain and monodomain models. In (Acta Appl.Math. 179 (2022) 1--35), we…

Analysis of PDEs · Mathematics 2022-09-16 Fakhrielddine Bader , Mostafa Bendahmane , Mazen Saad , Raafat Talhouk

Eating monitoring has remained an open challenge in medical research for years due to the lack of non-invasive sensors for continuous monitoring and the reliable methods for automatic behavior detection. In this paper, we present a pilot…

Machine Learning · Computer Science 2025-02-21 Xu-Lu Zhang , Zhen-Qun Yang , Dong-Mei Jiang , Ga Liao , Qing Li , Ramesh Jain , Xiao-Yong Wei

Electrocardiogram is a useful diagnostic signal that can detect cardiac abnormalities by measuring the electrical activity generated by the heart. Due to its rapid, non-invasive, and richly informative characteristics, ECG has many emerging…

Machine Learning · Computer Science 2025-12-09 Hanhui Deng , Xinglin Li , Jie Luo , Di Wu

An electrocardiogram (ECG) is a time-series signal that is represented by one-dimensional (1-D) data. Higher dimensional representation contains more information that is accessible for feature extraction. Hidden variables such as frequency…

Machine Learning · Statistics 2019-04-12 K. S. Rajput , S. Wibowo , C. Hao , M. Majmudar

Clinical oriented applications of computational electrocardiology require efficient and reliable identification of patient-specific parameters of mathematical models based on available measures. In particular, the estimation of cardiac…

Numerical Analysis · Mathematics 2016-11-01 Huanhuan Yang , Alessandro Veneziani

We study two-state (dichotomous, telegraph) random ergodic continuous-time processes with dynamics depending on their past. We take into account the history of process in an explicit form by introducing an integral non-local memory term…

Statistical Mechanics · Physics 2024-02-20 S. S. Apostolov , O. V. Usatenko , V. A. Yampol'skii , S. S. Melnyk , P. Grigolini , A. Krokhin

The arterial system dynamically loads the heart through changes in arterial compliance. The pressure-volume relation of arteries is known to be nonlinear, but arterial compliance is often modeled as a constant value, due to ease of…

Quantitative Methods · Quantitative Biology 2014-03-26 Timothy S. Phan , John K-J. Li

The inverse mechano-electrical problem in cardiac electrophysiology is the attempt to reconstruct electrical excitation or action potential wave patterns from the heart's mechanical deformation that occurs in response to electrical…

Image and Video Processing · Electrical Eng. & Systems 2021-11-10 Jan Christoph , Jan Lebert
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