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A new model is suggested and used to mimic various spatial or temporal designs in biological or non biological formations where the focus is on the normal or irregular electrical signals coming from human heart (ECG) or brain (EEG). The…
We propose a boundary element method for the accurate solution of the cell-by-cell bidomain model of electrophysiology. The cell-by-cell model, also called Extracellular-Membrane-Intracellular (EMI) model, is a system of reaction-diffusion…
The complex dynamics of the heart are reflected in its electrical activity, captured through electrocardiograms (ECGs). In this study we use nonlinear time series analysis to understand how ECG complexity varies with cardiac pathology.…
This paper proposes a data-driven model for solving the inverse problem of electrocardiography, the mathematical problem that forms the basis of electrocardiographic imaging (ECGI). We present a conditional diffusion framework that learns a…
We present a Bayesian approach to estimate the parameters of mathematical models of cardiac electrophysiology with quantified uncertainty. Such models capture the dynamics of the electrical signal that coordinates the muscle cell…
This PhD thesis develops an integrated mathematical model for autonomic nervous system control on cardiovascular activity. The model extensively covers cardiovascular neural pathways including a wide range of afferent sensory neurons,…
Electrocardiogram (ECG) signals, profiling the electrical activities of the heart, are used for a plethora of diagnostic applications. However, ECG systems require multiple leads or channels of signals to capture the complete view of the…
Myocardial infarction (MI) is a leading cause of death, and its adverse outcomes are urgent to predict. Yet ECG-based prognostic models underperform because deep learning requires large, labelled datasets, which are scarce in medicine.…
The T-wave of an electrocardiogram (ECG) represents the ventricular repolarization that is critical in restoration of the heart muscle to a pre-contractile state prior to the next beat. Alterations in the T-wave reflect various cardiac…
The electrocardiogram (ECG) has always been an important biomedical test to diagnose cardiovascular diseases. Current approaches for ECG monitoring are based on body attached electrodes leading to uncomfortable user experience. Therefore,…
Echocardiography video is a primary modality for diagnosing heart diseases, but the limited data poses challenges for both clinical teaching and machine learning training. Recently, video generative models have emerged as a promising…
The eikonal equation has become an indispensable tool for modeling cardiac electrical activation accurately and efficiently. In principle, by matching clinically recorded and eikonal-based electrocardiograms (ECGs), it is possible to build…
The Extracellular-Membrane-Intracellular (EMI) model is a novel mathematical framework for cardiac electrophysiology simulations. The EMI model provides a more detailed description of the heart's electrical activity compared to traditional…
Excitable membranes are an important type of nonlinear dynamical system and their study can be used to provide a connection between physical and biological circuits. We discuss two models of excitable membranes important in cardiac and…
Analyzing electrocardiography (ECG) data is essential for diagnosing and monitoring various heart diseases. The clinical adoption of automated methods requires accurate confidence measurements, which are largely absent from existing…
Based on recent experiments with time-lapse fluorescent imaging, we propose a cellular automaton model for the dynamics of vascular endothelial cells (ECs) in angiogenic morphogenesis. The model successfully reproduces cell mixing behavior,…
We review some of the latest approaches to analysing cardiac electrophysiology data using machine learning and predictive modelling. Cardiac arrhythmias, particularly atrial fibrillation, are a major global healthcare challenge. Treatment…
Objective: Exploit accelerometry data for an automatic, reliable, and prompt detection of spontaneous circulation during cardiac arrest, as this is both vital for patient survival and practically challenging. Methods: We developed a machine…
Biophysical signals such as Electrocardiogram (ECG) and Photoplethysmogram (PPG) are key to the sensing of vital parameters for wellbeing. Coincidentally, ECG and PPG are signals, which provide a "different window" into the same phenomena,…
Electrocardiogram (ECG), a non-invasive and affordable tool for cardiac monitoring, is highly sensitive in detecting acute heart attacks. However, due to the lengthy nature of ECG recordings, numerous machine learning methods have been…