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Nowadays, explosive synchronization is a well documented phenomenon occurring in networks when the node frequency and its degree are correlated. This first-order transition, which may coexists with classical synchronization, has been…
For many natural and engineered systems, a central function or design goal is the synchronization of one or more rhythmic or oscillating processes to an external forcing signal, which may be periodic on a different time-scale from the…
Music has been shown to enhance motor control in patients with Parkinson's disease (PD). Notably, musical rhythm is perceived as an external auditory cue that helps PD patients to better control movements. The rationale of such effects is…
Neurons communicate with downstream systems via sparse and incredibly brief electrical pulses, or spikes. Using these events, they control various targets such as neuromuscular units, neurosecretory systems, and other neurons in connected…
Critical dynamics are assumed to be an attractive mode for normal brain functioning as information processing and computational capabilities are found to be optimized there. Recent experimental observations of neuronal activity patterns…
We show that the unavoidable increase in neuronal response latency to ongoing stimulation serves as a nonuniform gradual stretching of neuronal circuit delay loops and emerges as an essential mechanism in the formation of various types of…
A network of propagating nonlinear oscillatory modes (waves) in the human brain is shown to generate collectively synchronized spiking activity (hypersynchronous spiking) when both amplitude and phase coupling between modes are taken into…
With the advancement in artificial intelligence (AI) and machine learning (ML) techniques, researchers are striving towards employing these techniques for advancing clinical practice. One of the key objectives in healthcare is the early…
Cortical network functioning critically depends on finely tuned interactions to afford neuronal activity propagation over long distances while avoiding runaway excitation. This importance is highlighted by the pathological consequences and…
Absence epilepsy is believed to be associated with the abnormal interactions between the cerebral cortex and thalamus. Besides the direct coupling, anatomical evidence indicates that the cerebral cortex and thalamus also communicate…
It is delightful to observe the emergence of synchronization in the blinking of fireflies to attract partners and preys. Other charming examples of synchronization can also be found in a wide range of phenomena such as, e.g., neurons…
Spontaneous synchronization is a general phenomenon in which a large population of coupled oscillators of diverse natural frequencies self-organize to operate in unison. The phenomenon occurs in physical and biological systems over a wide…
The study involved 56 patients with advanced and late stages of Parkinsons disease, which could be considered as potentially requiring neurosurgical treatment-electrical stimulation of deep brain structures. An algorithm has been developed…
Therapeutic intervention in neurological disorders still relies heavily on pharmacological solutions, while the treatment of patients with drug resistance remains an open challenge. This is particularly true for patients with epilepsy, 30%…
Epilepsy is one of the most occurring neurological diseases. The main characteristic of this disease is a frequent seizure, which is an electrical imbalance in the brain. It is generally accompanied by shaking of body parts and even leads…
Whole-brain models offer a promising method of predicting seizure spread, which is critical for successful surgery treatment of focal epilepsy. Existing methods are largely based on structural connectome, which ignores the effects of…
Epilepsy is a common, chronic neurological disorder characterized by recurrent seizures caused by sudden bursts of abnormal electrical activity in the brain. Seizures can often be unpredictable, leading to uncertainty and anxiety for people…
Epilepsy is one of the most common neurological disorders affecting up to 1% of the world's population and approximately 2.5 million people in the United States. Seizures in more than 30% of epilepsy patients are refractory to…
The spiking activity of neocortical neurons exhibits a striking level of variability, even when these networks are driven by identical stimuli. The approximately Poisson firing of neurons has led to the hypothesis that these neural networks…
Identifying seizure activities in non-stationary electroencephalography (EEG) is a challenging task, since it is time-consuming, burdensome, and dependent on expensive human resources and subject to error and bias. A computerized seizure…