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The matrix form of the presentation of the genetic code is described as the cognitive form to analyze structures of the genetic code. A similar matrix form is utilized in the theory of signal processing. The Kronecker family of the genetic…

Other Quantitative Biology · Quantitative Biology 2010-12-30 Sergey V. Petoukhov

The algebraic structures of the genetic code are most important to obtain additional information about the semantic code and its applications. In this paper we define two dual Boolean codon lattices of the genetic code using hydrogen bond…

Quantitative Methods · Quantitative Biology 2007-05-23 Robersy Sanchez , Eberto Morgado , Ricardo Grau

The genetic code has a high level of error robustness. Using values of hydrophobicity scales as a proxy for amino acid character, and the Mean Square measure as a function quantifying error robustness, a value can be obtained for a genetic…

Populations and Evolution · Quantitative Biology 2013-09-19 Harry Buhrman , Peter T. S. van der Gulik , Gunnar W. Klau , Christian Schaffner , Dave Speijer , Leen Stougie

We present a computer simulation, which is inspired by Penna model, to help understanding the effect of genetic coding tables on population dynamics. To represent populations we used real and artificial gene sequences in this model. We…

Populations and Evolution · Quantitative Biology 2007-07-16 E. Gultepe , M. L. Kurnaz

The genetic code is connection between 64 codons, which are building blocks of the genes, and 20 amino acids, which are building blocks of the proteins. In addition to coding amino acids, a few codons code stop signal, which is at the end…

Other Quantitative Biology · Quantitative Biology 2012-02-14 Branko Dragovich

Complex systems with tightly coadapted parts frequently appear in living systems and are difficult to account for through Darwinian evolution, that is random variation and natural selection, if the constituent parts are independently coded…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 John F. McGowan , Ph. D

A system-level genetic code is a hypothetical genetic code that exclusively or preferentially codes systems of interacting coadapted parts. System-level genetic codes differ from part-level genetic codes in which each discrete part is coded…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 John F. McGowan

The rules that specify how the information contained in DNA codes amino acids, is called "the genetic code". Using a simplified version of the Penna nodel, we are using computer simulations to investigate the importance of the genetic code…

Genomics · Quantitative Biology 2009-11-10 E. Gultepe , M. L. Kurnaz

How robust is the natural genetic code with respect to mistranslation errors? It has long been known that the genetic code is very efficient in limiting the effect of point mutation. A misread codon will commonly code either for the same…

Biological Physics · Physics 2009-11-03 Dimitri Gilis , Serge Massar , Nicolas Cerf , Marianne Rooman

A heuristic diagram of the evolution of the standard genetic code is presented. It incorporates, in a way that resembles the energy levels of an atom, the physical notion of broken symmetry and it is consistent with original ideas by Crick…

Other Quantitative Biology · Quantitative Biology 2015-12-31 C. Manuel Carlevaro , Ramiro M. Irastorza , Fernando Vericat

The macromolecules that encode and translate information in living systems, DNA and RNA, exhibit distinctive structural asymmetries, including homochirality or mirror image asymmetry and $3' - 5'$ directionality, that are invariant across…

Biomolecules · Quantitative Biology 2017-03-10 Hemachander Subramanian , Robert A. Gatenby

In this work it is shown that 20 canonical amino acids (AAs) within genetic code appear to be a whole system with strict AAs positions; more exactly, with AAs ordinal number in three variants; first variant 00-19, second 00-21 and third…

Other Quantitative Biology · Quantitative Biology 2015-06-26 Zvonimir M. Damjanovic , Miloje M. Rakocevic

A hypothesis of the evolution of the genetic code is proposed, the leading mechanism of which is the nucleotide spontaneous damage leading to AT-enrichment of the genome. The hypothesis accounts for stability of the genetic code towards…

Populations and Evolution · Quantitative Biology 2007-10-03 Denis A. Semenov

In this short paper, it is shown that the multiplet structure of the standard genetic code is derivable from the total number of nucleotides contained in 64 codons, 192, a small number. The degeneracy class-number is derived as the number…

Other Quantitative Biology · Quantitative Biology 2012-07-17 Tidjani Negadi

Living organisms are the most complex, interesting and significant objects regarding all substructures of the universe. Life science is regarded as a science of the 21st century and one can expect great new discoveries in the near futures.…

Other Quantitative Biology · Quantitative Biology 2009-11-23 Branko Dragovich

There is an intrinsic relationship between the molecular evolution in primordial period and the properties of genomes and proteomes of contemporary species. The genomic data may help us understand the driving force of evolution of life at…

Genomics · Quantitative Biology 2009-11-25 Dirson Jian Li , Shengli Zhang

In computer science, we can theoretically neatly separate transmission and processing of information, hardware and software, and programs and their inputs. This is much more intricate in biology, Nevertheless, I argue that Shannon's concept…

Populations and Evolution · Quantitative Biology 2020-11-02 Jürgen Jost

In this work, we look at the symmetry of normal modes in symmetric structures, particularly structures with cyclic symmetry. We show that normal modes of symmetric structures have different levels of symmetry, or symmetricity. One novel…

Biological Physics · Physics 2016-09-21 Guang Song

Many cases of non-standard genetic codes are known in mitochondrial genomes. We carry out analysis of phylogeny and codon usage of organisms for which the complete mitochondrial genome is available, and we determine the most likely…

Populations and Evolution · Quantitative Biology 2007-07-17 Supratim Sengupta , Xiaoguang Yang , Paul G. Higgs

A primordial genetic code is proposed, having only four codons assigned, GGC meaning glycine, GAC meaning aspartate/glutamate, GCC meaning alanine-like and GUC meaning valine-like. Pathways of ambiguity reduction enlarged the codon…

Populations and Evolution · Quantitative Biology 2007-11-06 Peter van der Gulik