Related papers: On a diffuse interface model for tumour growth wit…
A novel numerical technique has been proposed to solve a two-phase tumour growth model in one spatial dimension without needing to account for the boundary dynamics explicitly. The equivalence to the standard definition of a weak solution…
We analyze a system of cross-diffusion equations that models the growth of an avascular-tumor spheroid. The model incorporates two nonlinear diffusion effects, degeneracy type and super diffusion. We prove the global existence of weak…
We study an evolutionary system of Cahn-Hilliard-Darcy type including mass source and transport effects. The system may arise in a number of physical situations related to phase separation phenomena with convection, with the main and most…
We provide a rigorous mathematical framework to establish the limit of a nonlocal model of cell-cell adhesion system to a local model. When the parameter of the nonlocality goes to 0, the system tends to a Cahn-Hilliard system with…
Recently we considered a stochastic discrete model which describes fronts of cells invading a wound \cite{KSS}. In the model cells can move, proliferate, and experience cell-cell adhesion. In this work we focus on a continuum description of…
In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…
We analyze a diffuse interface model that describes the dynamics of incompressible two-phase flows influenced by interactions with a soluble chemical substance, encompassing the chemotaxis effect, mass transport, and reactions. In the…
The Functionalized Cahn-Hilliard equation has been proposed as a model for the interfacial energy of phase-separated mixtures of amphiphilic molecules. We study the existence of a nonnegative weak solutions of a gradient flow of the…
Pattern formation exhibited by a two-dimensional reaction-diffusion system in the fast inhibitor limit is considered from the point of view of interface motion. A dissipative nonlocal equation of motion for the boundary between high and low…
We consider a particular phase field system which physical context is that of tumor growth dynamics. The model we deal with consists of a Cahn-Hilliard type equation governing the evolution of the phase variable which takes into account the…
We define a new model of interface roughening which has the property that the minimum of interface height is conserved locally during the growth. This model corresponds to the limit $q \to \infty$ of the q-color dimer deposition-evaporation…
In the present article we demonstrate a new hybrid model of tumor growth. Our model is stochastic by tumor population development and strongly deterministic in cell motility dynamics and spatial propagation. In addition, it has excellent…
The problem of the onset and growth of solid tumour in homogeneous tissue is regarded using an approach based on local interaction between the tumoral and the sane tissue cells. The characteristic sizes and growth rates of spherical…
We propose a model for describing the growth on an untreated tumor, which is characterized in a simple way by a minimal number of parameters with a well-defined physical interpretation. The model is motivated by invoking the Master Equation…
In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…
We extend the doubly degenerate Cahn-Hilliard (DDCH) models for isotropic surface diffusion, which yield more accurate approximations than classical degenerate Cahn-Hilliard (DCH) models, to the anisotropic case. We consider both weak and…
We propose a dynamical system of tumor cells proliferation based on operatorial methods. The approach we propose is quantum-like: we use ladder and number operators to describe healthy and tumor cells birth and death, and the evolution is…
We investigate a class of systems of partial differential equations with nonlinear cross-diffusion and nonlocal interactions, which are of interest in several contexts in social sciences, finance, biology, and real world applications.…
We employ a generalization of Einstein's random walk paradigm for diffusion to derive a class of multidimensional degenerate nonlinear parabolic equations in non-divergence form. Specifically, in these equations, the diffusion coefficient…
We study a thermodynamically consistent diffuse-interface model that describes the motion of two macroscopically immiscible, incompressible, and viscous Newtonian fluids with unmatched densities. This model is compatible with continuum…