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The purpose of this work is to develop viable procedures for verifying the applicability of personalized dosimetry in computed tomography (CT) using Monte Carlo-based simulations. Mobile equipment together with customized software was…

The imaging performance of a high-resolution preclinical microPET system employing liquid xenon as the gamma ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection…

Medical Physics · Physics 2012-03-23 A. Miceli , J. Glister , A. Andreyev , D. Bryman , L. Kurchaninov , P. Lu , A. Muennich , F. Retiere , V. Sossi

We test the feasibility of calculating proton stopping power (SP) from a set of virtual monochromatic (VM) CT images, created with Monte Carlo-generated CT scans, using a dual-energy CT-to-SP procedure. The Monte Carlo CT simulations, with…

Medical Physics · Physics 2022-06-23 Adam Zieser , Ugur Akgun , Yasar Onel

Our interest has been to study the effect that scattered radiation has on contrast, signal-to-noise ratio and thickness reconstruction in digital mammographies. Using the GEANT code we have performed Monte-Carlo simulations of 25 kVp Mo/Mo…

Medical Physics · Physics 2009-09-29 Varlen Grabski , Maria-Ester Brandan

Iterative methods for tomographic image reconstruction have great potential for enabling high quality imaging from low-dose projection data. The computational burden of iterative reconstruction algorithms, however, has been an impediment in…

Image and Video Processing · Electrical Eng. & Systems 2019-07-25 Kai Zhang , Alireza Entezari

X-ray cone-beam computed tomography (CT) has the notable features such as high efficiency and precision, and is widely used in the fields of medical imaging and industrial non-destructive testing, but the inherent imaging degradation…

Optics · Physics 2015-06-19 Hua Zhang , Kuidong Huang , Yikai Shi , Zhe Xu

Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can…

The measurement of the time of flight of the two 511 keV gammas recorded in coincidence in a PET scanner provides an effective way of reducing the random background and therefore increases the scanner sensitivity, provided that the…

Instrumentation and Detectors · Physics 2016-10-12 J. J Gomez-Cadenas , J. M. Benlloch-Rodríguez , P. Ferrario , F. Monrabal , J. Rodríguez , J. F. Toledo

The use of computed tomography (CT) imaging has become of increasing interest to academic areas outside of the field of medical imaging and industrial inspection, e.g., to biology and cultural heritage research. The pecularities of these…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Florian Schiffers , Thomas Bochynek , Andre Aichert , Tobias Würfl , Michael Rubenstein , Oliver Cossairt

Cone beam computed tomography (CBCT) for breast imaging has potential to replace conventional mammograms. However, concerns over dose and image quality prevent CBBCT systems from the clinical trial phase to next stage. The time of flight…

Medical Physics · Physics 2021-02-01 Ignacio O. Romero , Changqing Li

Image reconstruction in Single Photon Emission Computed Tomography (SPECT) is affected by physical effects such as photon attenuation, Compton scatter and detector response. These effects can be compensated for by modeling the corresponding…

Medical Physics · Physics 2009-11-11 Z. El Bitar , D. Lazaro , C. Coello , V. Breton , D. Hill , I. Buvat

The XCAT phantom is a realistic 4D digital torso phantom that is widely used in imaging and therapy research. However, lung mass is not conserved between respiratory phases of the phantom, making detailed dosimetric simulations and dose…

X-ray micro tomography is a non-destructive, three-dimensional inspection technique applied across a vast range of fields and disciplines, ranging from research to industrial, encompassing engineering, biology and medical research.…

In computed tomography (CT) reconstruction, scattering causes server quality degradation of the reconstructed CT images by introducing streaks and cupping artifacts which reduce the detectability of low contrast objects. Monte Carlo (MC)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Ammar Alsaffar , Steffen Kieß , Kaicong Sun , Sven Simon

The rapid development of X-ray astronomy has been made possible by widely deploying X-ray focusing telescopes on board many X-ray satellites. Geant4 is a very powerful toolkit for Monte Carlo simulations and has remarkable abilities to…

Instrumentation and Methods for Astrophysics · Physics 2017-03-29 Donghua Zhao , Chen Zhang , Weimin Yuan , Shuangnan Zhang , Richard Willingale , Zhixing Ling

X-Ray based computed tomography (CT) is a well-established technique for determining the three-dimensional structure of an object from its two-dimensional projections. In the past few decades, there have been significant advancements in the…

Medical Physics · Physics 2023-04-26 Dinesh Kumar , Dilworth Y. Parkinson , Jeffrey J. Donatelli

We previously demonstrated near-field speckle scanning based x-ray imaging to be an easy-to-implement phase sensing method capable of providing both high sensitivity and high resolution. Yet, this performance combination could only be…

Medical Physics · Physics 2017-06-21 Sebastien Berujon , Eric Ziegler

Reconstructing the shape and appearance of real-world objects using measured 2D images has been a long-standing problem in computer vision. In this paper, we introduce a new analysis-by-synthesis technique capable of producing high-quality…

Computer Vision and Pattern Recognition · Computer Science 2021-06-28 Fujun Luan , Shuang Zhao , Kavita Bala , Zhao Dong

X-ray based imaging modalities are widely used in research, industry, and in the medical field. Consequently, there is a strong motivation to improve their performances with respect to resolution, dose, and contrast. Ghost imaging (GI) is…

Applied Physics · Physics 2023-06-30 R. H. Shukrun , Y. Klein. , O. Sefi. , Y. Fried. , L. Epstein. , S. Shwartz

Flattening filter free (FFF) beams due to their non-uniformity, are sub-optimal for larger field sizes. The purpose of this study was to investigate the incident electron beam distributions that would produce flat FFF beams without the use…

Medical Physics · Physics 2015-06-16 Sergei Zavgorodni