Related papers: Spontaneous Activity in the Visual Cortex is Organ…
The neural networks of the human brain act as very efficient parallel processing computers co-ordinating memory related responses to a multitude of input signals from sensory organs. Information storage, update and appropriate retrieval are…
The co-occurrence of action potentials of pairs of neurons within short time intervals is known since long. Such synchronous events can appear time-locked to the behavior of an animal and also theoretical considerations argue for a…
Distributed networks of brain areas interact with one another in a time-varying fashion to enable complex cognitive and sensorimotor functions. Here we use novel network analysis algorithms to test the recruitment and integration of…
Cortical activity in-vivo displays relaxational time scales much longer than the membrane time constant of the neurons or the deactivation time of ionotropic synaptic conductances. The mechanisms responsible for such slow dynamics are not…
Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…
The human brain is a complex network of interconnected brain regions organized into functional modules with distinct roles in cognition and behavior. An important question concerns the persistence and stability of these modules over the…
Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…
Self-sustained activity in the brain is observed in the absence of external stimuli and contributes to signal propagation, neural coding, and dynamic stability. It also plays an important role in cognitive processes. In this work, by means…
In vivo, neurons establish functional connections and preserve information along their synaptic pathways from one information processing stage to the next in a very efficient manner. Paired spiking (PS) enhancement plays a key role by…
Neurons in the primary visual cortex are more or less selective for the orientation of a light bar used for stimulation. A broad distribution of individual grades of orientation selectivity has in fact been reported in all species. A…
Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…
Anatomic connections between brain areas affect information flow between neuronal circuits and the synchronization of neuronal activity. However, such structural connectivity does not coincide with effective connectivity, related to the…
Dynamical wiring and rewiring in neural networks are carried out by activity-dependent growth and retraction of axons and dendrites, guided by gudance molecules, released by target cells. Experience-dependent structural changes in cortical…
In the last century, most sensorimotor studies of cortical neurons relied on average firing rates. Rate coding is efficient for fast sensorimotor processing that occurs within a few seconds. Much less is known about the neural mechanisms…
The brain is a paradigmatic example of a complex system as its functionality emerges as a global property of local mesoscopic and microscopic interactions. Complex network theory allows to elicit the functional architecture of the brain in…
Maintaining upright posture is a complex task governed by the integration of afferent sensorimotor and visual information with compensatory neuromuscular reactions. The objective of this work was to characterize the visual dependency and…
During development, the mammalian brain differentiates into specialized regions with distinct functional abilities. While many factors contribute to functional specialization, we explore the effect of neuronal density on the development of…
Visual recognition takes a small fraction of a second and relies on the cascade of signals along the ventral visual stream. Given the rapid path through multiple processing steps between photoreceptors and higher visual areas, information…
A brain microstate is characterized by a unique, fixed spatial distribution of electrically active neurons with time varying amplitude. It is hypothesized that a microstate implements a functional/physiological state of the brain during…
Many cortical areas increase in size considerably during postnatal development, progressively displacing neuronal cell bodies from each other. At present, little is known about how cortical growth affects the development of neuronal…