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Accurate modeling of the patient flow within an Emergency Department (ED) is required by all studies dealing with the increasing and well-known problem of overcrowding. Since Discrete Event Simulation (DES) models are often adopted with the…

Optimization and Control · Mathematics 2021-02-02 A. De Santis , T. Giovannelli , S. Lucidi , M. Messedaglia , M. Roma

Over the course of the past two decades, a substantial body of research has substantiated the viability of utilising cardiac signals as a biometric modality. This paper presents a novel approach for patient identification in healthcare…

Machine Learning · Computer Science 2024-11-27 Caterina Fuster-Barceló , Carmen Cámara , Pedro Peris-López

Applications that fuse machine learning and simulation can benefit from the use of multiple computing resources, with, for example, simulation codes running on highly parallel supercomputers and AI training and inference tasks on…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-12-04 Logan Ward , J. Gregory Pauloski , Valerie Hayot-Sasson , Ryan Chard , Yadu Babuji , Ganesh Sivaraman , Sutanay Choudhury , Kyle Chard , Rajeev Thakur , Ian Foster

The recent increase in the availability of medical data, possible through automation and digitization of medical equipment, has enabled more accurate and complete analysis on patients' medical data through many branches of data science. In…

Healthcare AI holds the potential to increase patient safety, augment efficiency and improve patient outcomes, yet research is often limited by data access, cohort curation, and tooling for analysis. Collection and translation of electronic…

Software Engineering · Computer Science 2021-12-14 Raphael Y. Cohen , Vesela P. Kovacheva

Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative…

Machine Learning · Statistics 2019-02-12 Zihao Zhu , Changchang Yin , Buyue Qian , Yu Cheng , Jishang Wei , Fei Wang

The discipline of process mining has a solid track record of successful applications to the healthcare domain. Within such research space, we conducted a case study related to the Intensive Care Unit (ICU) ward of the Uniklinik Aachen…

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

Recent years have seen an increased focus into the tasks of predicting hospital inpatient risk of deterioration and trajectory evolution due to the availability of electronic patient data. A common approach to these problems involves…

Machine Learning · Computer Science 2020-11-18 Henrique Aguiar , Mauro Santos , Peter Watkinson , Tingting Zhu

Background: Patient recruitment in clinical trials is hindered by complex eligibility criteria and labor-intensive chart reviews. Prior research using text-only models have struggled to address this problem in a reliable and scalable way…

Computation and Language · Computer Science 2025-03-20 Anatole Callies , Quentin Bodinier , Philippe Ravaud , Kourosh Davarpanah

Background: More than half (57%) of pharma clinical research spend is in support of clinical trials. One reason is that Electronic Health Record (EHR) systems and HIPAA privacy rules often limit how broadly patient information can be…

Quantitative Methods · Quantitative Biology 2018-07-03 Andrew J McMurry , Richen Zhang , Alex Foxman , Lawrence Reiter , Ronny Schnel , DeLeys Brandman

We introduce a novel profile-based patient clustering model designed for clinical data in healthcare. By utilizing a method grounded on constrained low-rank approximation, our model takes advantage of patients' clinical data and digital…

Machine Learning · Computer Science 2023-08-24 Dongjin Choi , Andy Xiang , Ozgur Ozturk , Deep Shrestha , Barry Drake , Hamid Haidarian , Faizan Javed , Haesun Park

In the current study, the authors demonstrate the method aimed at analyzing the distribution of acute coronary syndrome (ACS) cases in Saint Petersburg using the synthetic population approach and a statistical model for arterial…

Quantitative Methods · Quantitative Biology 2020-04-15 Vasiliy N. Leonenko

Within Process mining, discovery techniques had made it possible to construct business process models automatically from event logs. However, results often do not achieve the balance between model complexity and its fitting accuracy, so…

Artificial Intelligence · Computer Science 2023-01-18 Liubov O. Elkhovskaya , Alexander D. Kshenin , Marina A. Balakhontceva , Sergey V. Kovalchuk

Many patients with advanced cancers undergo multiple lines of treatment. We develop methods for estimating quality-adjusted outcomes and cost-effectiveness of therapy sequences, informed by patient-level longitudinal data from Electronic…

Quantitative Methods · Quantitative Biology 2024-12-20 Elizabeth A. Handorf , J. Robert Beck , Daniel M. Geynisman

Machine learning for data-driven diagnosis has been actively studied in medicine to provide better healthcare. Supporting analysis of a patient cohort similar to a patient under treatment is a key task for clinicians to make decisions with…

Medical Physics · Physics 2020-03-25 Rongchen Guo , Takanori Fujiwara , Yiran Li , Kelly M. Lima , Soman Sen , Nam K. Tran , Kwan-Liu Ma

Patient similarity assessment, which identifies patients similar to a given patient, can help improve medical care. The assessment can be performed using Electronic Medical Records (EMRs). Patient similarity measurement requires converting…

Information Retrieval · Computer Science 2022-09-20 Hoda Memarzadeh , Nasser Ghadiri , Matthias Samwald , Maryam Lotfi Shahreza

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

Biological Physics · Physics 2023-02-27 Toby Simpson

Healthcare providers face significant challenges with monitoring and managing patient data outside of clinics, particularly with insufficient resources and limited feedback on their patients' conditions. Effective management of these…

Databases · Computer Science 2023-11-14 Daniel Bloor , Nnamdi Ugwuoke , David Taylor , Keir Lewis , Luis Mur , Chuan Lu

Digital twin technology has is anticipated to transform healthcare, enabling personalized medicines and support, earlier diagnoses, simulated treatment outcomes, and optimized surgical plans. Digital twins are readily gaining traction in…

Machine Learning · Computer Science 2023-07-12 Logan Nye