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Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Since genes are the foundation of cellular life, building gene…

Quantitative Methods · Quantitative Biology 2025-05-09 Changxi Chi , Jun Xia , Jingbo Zhou , Jiabei Cheng , Chang Yu , Stan Z. Li

Covariate adjustment is a ubiquitous method used to estimate the average treatment effect (ATE) from observational data. Assuming a known graphical structure of the data generating model, recent results give graphical criteria for optimal…

Statistics Theory · Mathematics 2025-12-08 Alexander Mangulad Christgau , Anton Rask Lundborg , Niels Richard Hansen

In the context of an efficient network traffic engineering process where the network continuously measures a new traffic matrix and updates the set of paths in the network, an automated process is required to quickly and efficiently…

Networking and Internet Architecture · Computer Science 2022-12-23 Shahrooz Pouryousef , Lixin Gao , Don Towsley

Control theory has seen recently impactful applications in network science, especially in connections with applications in network medicine. A key topic of research is that of finding minimal external interventions that offer control over…

Molecular Networks · Quantitative Biology 2020-07-10 Victor-Bogdan Popescu , Krishna Kanhaiya , Iulian Năstac , Eugen Czeizler , Ion Petre

Off-policy evaluation and learning (OPE/L) use offline observational data to make better decisions, which is crucial in applications where online experimentation is limited. However, depending entirely on logged data, OPE/L is sensitive to…

Machine Learning · Computer Science 2022-07-19 Nathan Kallus , Xiaojie Mao , Kaiwen Wang , Zhengyuan Zhou

This paper studies reduced-order modeling of dynamic networks with strongly connected topology. Given a graph clustering of an original complex network, we construct a quotient graph with less number of vertices, where the edge weights are…

Optimization and Control · Mathematics 2020-03-10 Xiaodong Cheng , Lanlin Yu , Dingchao Ren , Jacquelien M. A. Scherpen

Random ordinary differential equations (RODEs), i.e. ODEs with random parameters, are often used to model complex dynamics. Most existing methods to identify unknown governing RODEs from observed data often rely on strong prior knowledge.…

Numerical Analysis · Mathematics 2020-06-04 Junyu Liu , Zichao Long , Ranran Wang , Jie Sun , Bin Dong

Biological systems are driven by intricate interactions among the complex array of molecules that comprise the cell. Many methods have been developed to reconstruct network models of those interactions. These methods often draw on large…

Molecular Networks · Quantitative Biology 2018-06-29 Marieke Lydia Kuijjer , Matthew Tung , GuoCheng Yuan , John Quackenbush , Kimberly Glass

Lightweight model design has become an important direction in the application of deep learning technology, pruning is an effective mean to achieve a large reduction in model parameters and FLOPs. The existing neural network pruning methods…

Machine Learning · Computer Science 2021-11-19 Zhuangzhi Chen , Jingyang Xiang , Yao Lu , Qi Xuan , Xiaoniu Yang

Gene covariation networks are commonly used to study biological processes. The inference of gene covariation networks from observational data can be challenging, especially considering the large number of players involved and the small…

Molecular Networks · Quantitative Biology 2019-04-17 Anatoly Yambartsev , Michael Perlin , Yevgeniy Kovchegov , Natalia Shulzhenko , Karina L. Mine , Xiaoxi Dong , Andrey Morgun

Cyber networks are fundamental to many organization's infrastructure, and the size of cyber networks is increasing rapidly. Risk measurement of the entities/endpoints that make up the network via available knowledge about possible threats…

Systems and Control · Electrical Eng. & Systems 2025-01-29 Arda Bayer , David Maluf , Behnaam Aazhang

We present FastRP, a scalable and performant algorithm for learning distributed node representations in a graph. FastRP is over 4,000 times faster than state-of-the-art methods such as DeepWalk and node2vec, while achieving comparable or…

Social and Information Networks · Computer Science 2019-09-02 Haochen Chen , Syed Fahad Sultan , Yingtao Tian , Muhao Chen , Steven Skiena

Nowadays, in the big data era, social networks, graph databases, knowledge graphs, electronic commerce etc. demand efficient and scalable capability to process an ever increasing volume of graph-structured data. To meet the challenge, two…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-10 Xiaole Wen , Shuai Zhang , Haihang You

Graph Representation Learning (GRL) methods opened new avenues for addressing complex, real-world problems represented by graphs. However, many graphs used in these applications comprise millions of nodes and billions of edges and are…

Reconstructing weighted networks from partial information is necessary in many important circumstances, e.g. for a correct estimation of systemic risk. It has been shown that, in order to achieve an accurate reconstruction, it is crucial to…

Physics and Society · Physics 2017-03-07 Tiziano Squartini , Giulio Cimini , Andrea Gabrielli , Diego Garlaschelli

Neural network compression empowers the effective yet unwieldy deep convolutional neural networks (CNN) to be deployed in resource-constrained scenarios. Most state-of-the-art approaches prune the model in filter-level according to the…

Computer Vision and Pattern Recognition · Computer Science 2019-06-26 Wenxiao Wang , Cong Fu , Jishun Guo , Deng Cai , Xiaofei He

Model compression is an essential technique for deploying deep neural networks (DNNs) on power and memory-constrained resources. However, existing model-compression methods often rely on human expertise and focus on parameters' local…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Sixing Yu , Arya Mazaheri , Ali Jannesari

This manuscript delves into the intersection of genomics and phenotypic prediction, focusing on the statistical innovation required to navigate the complexities introduced by noisy covariates and confounders. The primary emphasis is on the…

Methodology · Statistics 2024-11-15 Upama Paul Chowdhury , Ronit Bhattacharjee , Susmita Das , Abhik Ghosh

Social network analysis provides meaningful information about behavior of network members that can be used for diverse applications such as classification, link prediction. However, network analysis is computationally expensive because of…

Social and Information Networks · Computer Science 2018-07-30 Mohammad Mehdi Keikha , Maseud Rahgozar , Masoud Asadpour

Network representation learning (NRL) plays a vital role in a variety of tasks such as node classification and link prediction. It aims to learn low-dimensional vector representations for nodes based on network structures or node…

Social and Information Networks · Computer Science 2020-08-17 Ke Hou , Jiaying Liu , Yin Peng , Bo Xu , Ivan Lee , Feng Xia