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We consider the model-free feature screening in large-scale ultrahigh-dimensional data analysis. Existing feature screening methods often face substantial computational challenges when dealing with large sample sizes. To alleviate the…

Machine Learning · Statistics 2025-09-22 Xiaxue Ouyang , Xinlai Kang , Mengyu Li , Zhenxing Dou , Jun Yu , Cheng Meng

Independent component analysis (ICA) is a method for recovering statistically independent signals from observations of unknown linear combinations of the sources. Some of the most accurate ICA decomposition methods require searching for the…

Machine Learning · Statistics 2016-09-23 Matan Sela , Ron Kimmel

Learning directed acyclic graphs (DAGs) to identify causal relations underlying observational data is crucial but also poses significant challenges. Recently, topology-based methods have emerged as a two-step approach to discovering DAGs by…

Machine Learning · Computer Science 2023-08-17 Anpeng Wu , Haoxuan Li , Kun Kuang , Keli Zhang , Fei Wu

Given independent samples generated from the joint distribution $p(\mathbf{x},\mathbf{y},\mathbf{z})$, we study the problem of Conditional Independence (CI-Testing), i.e., whether the joint equals the CI distribution…

Machine Learning · Statistics 2018-06-27 Rajat Sen , Karthikeyan Shanmugam , Himanshu Asnani , Arman Rahimzamani , Sreeram Kannan

The PC algorithm uses conditional independence tests for model selection in graphical modeling with acyclic directed graphs. In Gaussian models, tests of conditional independence are typically based on Pearson correlations, and…

Statistics Theory · Mathematics 2012-07-03 Naftali Harris , Mathias Drton

High-dimensional variable selection is an important issue in many scientific fields, such as genomics. In this paper, we develop a sure independence feature screening pro- cedure based on kernel canonical correlation analysis (KCCA-SIS, for…

Methodology · Statistics 2016-10-04 Tianqi Liu , Kuang-Yao Lee , Hongyu Zhao

We consider the problem of inferring the directed, causal graph from observational data, assuming no hidden confounders. We take an information theoretic approach, and make three main contributions. First, we show how through algorithmic…

Machine Learning · Statistics 2018-09-07 Alexander Marx , Jilles Vreeken

Measuring conditional independence is one of the important tasks in statistical inference and is fundamental in causal discovery, feature selection, dimensionality reduction, Bayesian network learning, and others. In this work, we explore…

Statistics Theory · Mathematics 2020-08-18 Tianhong Sheng , Bharath K. Sriperumbudur

Test of independence plays a fundamental role in many statistical techniques. Among the nonparametric approaches, the distance-based methods (such as the distance correlation based hypotheses testing for independence) have numerous…

Methodology · Statistics 2017-01-24 Cheng Huang , Xiaoming Huo

Causal discovery, i.e., learning the causal graph from data, is often the first step toward the identification and estimation of causal effects, a key requirement in numerous scientific domains. Causal discovery is hampered by two main…

Machine Learning · Computer Science 2024-03-15 Ehsan Mokhtarian , Sepehr Elahi , Sina Akbari , Negar Kiyavash

Independence and Conditional Independence (CI) are two fundamental concepts in probability and statistics, which can be applied to solve many central problems of statistical inference. There are many existing independence and CI measures…

Methodology · Statistics 2022-05-17 Jian Ma

This paper is concerned with test of the conditional independence. We first establish an equivalence between the conditional independence and the mutual independence. Based on the equivalence, we propose an index to measure the conditional…

Methodology · Statistics 2021-05-18 Zhanrui Cai , Runze Li , Yaowu Zhang

We consider the problem of non-parametric Conditional Independence testing (CI testing) for continuous random variables. Given i.i.d samples from the joint distribution $f(x,y,z)$ of continuous random vectors $X,Y$ and $Z,$ we determine…

Randomized controlled trials (RCTs) are considered as the gold standard for testing causal hypotheses in the clinical domain. However, the investigation of prognostic variables of patient outcome in a hypothesized cause-effect route is not…

Conditional independence testing is a key problem required by many machine learning and statistics tools. In particular, it is one way of evaluating the usefulness of some features on a supervised prediction problem. We propose a novel…

Machine Learning · Statistics 2019-08-02 Marco Henrique de Almeida Inácio , Rafael Izbicki , Rafael Bassi Stern

Model-X approaches to testing conditional independence between a predictor and an outcome variable given a vector of covariates usually assume exact knowledge of the conditional distribution of the predictor given the covariates.…

Methodology · Statistics 2023-02-10 Ziang Niu , Abhinav Chakraborty , Oliver Dukes , Eugene Katsevich

We propose a series of computationally efficient nonparametric tests for the two-sample, independence, and goodness-of-fit problems, using the Maximum Mean Discrepancy (MMD), Hilbert Schmidt Independence Criterion (HSIC), and Kernel Stein…

Machine Learning · Statistics 2023-01-27 Antonin Schrab , Ilmun Kim , Benjamin Guedj , Arthur Gretton

Identifying causal interactions in complex dynamical systems is a fundamental challenge across the computational sciences. Existing functional connectivity methods capture correlations but not causation. While addressing directionality,…

Neurons and Cognition · Quantitative Biology 2026-03-10 Rahul Biswas , SuryaNarayana Sripada , Somabha Mukherjee , Reza Abbasi-Asl

Independence testing plays a central role in statistical and causal inference from observational data. Standard independence tests assume that the data samples are independent and identically distributed (i.i.d.) but that assumption is…

Machine Learning · Statistics 2022-07-04 Ragib Ahsan , Zahra Fatemi , David Arbour , Elena Zheleva

Causal inference grows increasingly complex as the number of confounders increases. Given treatments $X$, confounders $Z$ and outcomes $Y$, we develop a non-parametric method to test the \textit{do-null} hypothesis $H_0:\; p(y|\text{\it…

Methodology · Statistics 2024-06-04 Robert Hu , Dino Sejdinovic , Robin J. Evans
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