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DNA-based storage is an emerging technology that enables digital information to be archived in DNA molecules. This method enjoys major advantages over magnetic and optical storage solutions such as exceptional information density, enhanced…

Information Theory · Computer Science 2024-03-13 Daniella Bar-Lev , Itai Orr , Omer Sabary , Tuvi Etzion , Eitan Yaakobi

Recently, we have been witnessing huge advancements in the scale of data we routinely generate and collect in pretty much everything we do, as well as our ability to exploit modern technologies to process, analyze and understand this data.…

Databases · Computer Science 2017-09-25 Radwa Elshawi , Sherif Sakr

Advances in information technology and its widespread growth in several areas of business, engineering, medical and scientific studies are resulting in information/data explosion. Knowledge discovery and decision making from such rapidly…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-09-07 Raghavendra Kune , Pramodkumar Konugurthi , Arun Agarwal , Raghavendra Rao Chillarige , Rajkumar Buyya

Machine learning (ML), deep learning (DL), and artificial intelligence (AI) are of increasing importance in biomedicine. The goal of this work is to show progress in ML in digital health, to exemplify future needs and trends, and to…

Artificial Intelligence · Computer Science 2019-11-19 Fabian V. Filipp

The fall of prices of the high-throughput genome sequencing changes the landscape of modern genomics. A number of large scale projects aimed at sequencing many human genomes are in progress. Genome sequencing also becomes an important aid…

Data Structures and Algorithms · Computer Science 2017-03-03 Sebastian Deorowicz , Agnieszka Danek , Marcin Niemiec

Biology is at the precipice of a new era where AI accelerates and amplifies the ability to study how cells operate, organize, and work as systems, revealing why disease happens and how to correct it. Organizations globally are prioritizing…

The ominous warnings of a `data deluge' in the life sciences from high-throughput DNA sequencing data are being supplanted by a second deluge, of cliches bemoaning our collective scientific fate unless we address the genomic data `tsunami'.…

Genomics · Quantitative Biology 2013-08-16 Aaron Golden , S. George Djorgovski , John M. Greally

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

DNA sequence analysis is fundamental to life science research. The rapid development of next generation sequencing (NGS) technologies, and the richness and diversity of applications it makes feasible, have created an enormous gulf between…

Computational Engineering, Finance, and Science · Computer Science 2013-10-29 Shel Swenson , Yogesh Simmhan , Viktor Prasanna , Manish Parashar , Jason Riedy , David Bader , Richard Vuduc

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

Life finds a way. For sessile organisms like plants, the need to adapt to changes in the environment is even more poignant. For humanity, the need to develop crops that can grow in diverse environments and feed our growing population is an…

Quantitative Methods · Quantitative Biology 2024-08-15 Eugene Koh , Rohan Shawn Sunil , Hilbert Yuen In Lam , Marek Mutwil

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…

Databases · Computer Science 2025-09-22 Rosalia Moreddu

In order to associate complex traits with genetic polymorphisms, genome-wide association studies process huge datasets involving tens of thousands of individuals genotyped for millions of polymorphisms. When handling these datasets, which…

Computational Engineering, Finance, and Science · Computer Science 2013-05-02 Elmar Peise , Diego Fabregat , Yurii Aulchenko , Paolo Bientinesi

As datasets grow it becomes infeasible to process them completely with a desired model. For giant datasets, we frame the order in which computation is performed as a decision problem. The order is designed so that partial computations are…

Computation · Statistics 2014-03-18 Daniel John Lawson , Niall M Adams

The article deals with the problem which led to Big Data. Big Data information technology is the set of methods and means of processing different types of structured and unstructured dynamic large amounts of data for their analysis and use…

Databases · Computer Science 2019-05-07 Nataliya Shakhovska , Uyrii Bolubash , Oleh Veres

Rapid advancements in technology have led to an increased use of artificial intelligence (AI) technologies in medicine and bioinformatics research. In anticipation of this, the National Institutes of Health (NIH) assembled the Bridge to…

Other Quantitative Biology · Quantitative Biology 2025-12-15 Matthew Cannon , Wesley Goar , In-Hee Lee , James Stevenson , Amy Heiser , Nathan Sheffield , James Eddy , Monica Munoz-Torres , Sek Wong Kong , Alex H Wagner

The excessive amounts of data generated by devices and Internet-based sources at a regular basis constitute, big data. This data can be processed and analyzed to develop useful applications for specific domains. Several mathematical and…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-12-15 Samiya Khan , Kashish Ara Shakil , Mansaf Alam

The ability to collect and analyze large amounts of data is a growing problem within the scientific community. The growing gap between data and users calls for innovative tools that address the challenges faced by big data volume, velocity…

Databases · Computer Science 2016-08-01 Vijay Gadepally , Jeremy Kepner

Genomic data I used in many fields but, it has become known that most of the platforms used in the sequencing process produce significant errors. This means that the analysis and inferences generated from these data may have some errors…

Genomics · Quantitative Biology 2024-09-05 Ferdinand Kartriku , Robert Sowah , Charles Saah