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Phase separation within polymer networks plays a central role in shaping the structure and mechanics of both synthetic materials and living cells, including the formation of biomolecular condensates within cytoskeletal networks. Previous…

Soft Condensed Matter · Physics 2025-12-01 Takahiro Yokoyama , Yicheng Qiang , David Zwicker , Arash Nikoubashman

Emulsions ripen with an average droplet size increasing in time. In chemically active emulsions, coarsening can be absent, leading to a non-equilibrium steady state with mono-disperse droplet sizes. By considering a minimal model for phase…

Soft Condensed Matter · Physics 2024-09-06 Jonathan Bauermann , Giacomo Bartolucci , Job Boekhoven , Frank Jülicher , Christoph A. Weber

Controlled activity of active entities interacting with a passive environment can generate emergent system-level phenomena, positioning such systems as promising platforms for potential downstream applications in targeted drug delivery,…

Soft Condensed Matter · Physics 2025-10-07 Thomas Jacob , Siddhant Mohapatra , Rajalingam A , Sam Mathew , Pallab Sinha Mahapatra

Motility-induced phase separation (MIPS), the phenomenon in which purely repulsive active particles undergo a liquid-gas phase separation, is among the simplest and most widely studied examples of a nonequilibrium phase transition. Here, we…

Soft Condensed Matter · Physics 2021-05-11 Ahmad K. Omar , Katherine Klymko , Trevor GrandPre , Phillip L. Geissler

We study experimentally and numerically the motion of a self-phoretic active particle in two-dimensional (2D) loosely-packed colloidal crystals at fluid interfaces. Two scenarios emerge depending on the interaction between the active…

Soft Condensed Matter · Physics 2018-07-04 Kilian Dietrich , Ivo Buttinoni , Giovanni Volpe , Lucio Isa

A simple theoretical approach is used to investigate active colloids at the free interface and near repulsive substrates. We employ dynamical density functional theory to determine the steady-state density profiles in an effective…

Soft Condensed Matter · Physics 2017-02-03 René Wittmann , Joseph M. Brader

Chemically active droplets provide simple models for cell-like systems that can grow and divide. Such active droplet systems are driven away from thermodynamic equilibrium and turn over chemically, which corresponds to a simple metabolism.…

Biological Physics · Physics 2022-09-28 Jonathan Bauermann , Christoph A. Weber , Frank Jülicher

In order to understand the nuclei which develop during the course of protein folding and unfolding, we examine phase segregation of a single heteropolymer chain which occurs in equilibrium. These segregated conformations are characterized…

Disordered Systems and Neural Networks · Physics 2009-10-31 Rose Du , Alexander Yu. Grosberg , Toyoichi Tanaka

Recent theories predict phase separation among orientationally disordered active particles whose propulsion speed decreases rapidly enough with density. Coarse-grained models of this process show time-reversal symmetry (detailed balance) to…

Active matter comprised of many self-driven units can exhibit emergent collective behaviors such as pattern formation and phase separation in both biologica and synthetic systems. While these behaviors are increasingly well understood for…

Soft Condensed Matter · Physics 2015-07-27 Syeda Sabrina , Matthew Spellings , Sharon C. Glotzer , Kyle J. M. Bishop

Phase separation in biomolecular mixtures can result from multiple physical interactions, which may act either complementarily or antagonistically. In the case of protein-nucleic acid mixtures, charge plays a key role but can have…

Soft Condensed Matter · Physics 2026-05-13 Gabrielle R. Abraham , Tianhao Li , Anna Nguyen , William M. Jacobs , Omar A. Saleh

We consider a model of an extensible semiflexible filament moving in two dimensions on a motility assay of motor proteins represented explicitly as active harmonic linkers. Their heads bind stochastically to polymer segments within a…

Biological Physics · Physics 2021-08-31 Amir Shee , Nisha Gupta , Abhishek Chaudhuri , Debasish Chaudhuri

We study polymer-polymer phase separation in a common good solvent by means of Monte Carlo simulations of the bond-fluctuation model. Below a critical, chain-length dependent concentration, no phase separation occurs. For higher…

Soft Condensed Matter · Physics 2009-11-11 Lei Guo , Erik Luijten

We model a binary mixture of passive and active Brownian particles in two dimensions using the effective interaction between passive particles in the active bath. The activity of active particles and the size ratio of two types of particles…

Soft Condensed Matter · Physics 2022-06-15 Jay Prakash Singh , Sudipta Pattanayak , Shradha Mishra , Jaydeb Chakrabarti

Accurate interaction potentials between microscopic components such as colloidal particles or cells are crucial to understanding a range of processes, including colloidal crystallization, bacterial colony formation, and cancer metastasis.…

The influence of size differences, shape, mass and persistent motion on phase separation in binary mixtures has been intensively studied. Here we focus on the exclusive role of diffusivity differences in binary mixtures of equal-sized…

Soft Condensed Matter · Physics 2016-03-04 Simon N. Weber , Christoph A. Weber , Erwin Frey

We study a two-dimensional model of an active isotropic colloid whose propulsion is linked to the interactions between solute particles of the bath. The colloid catalyzes a chemical reaction in its vicinity, that yields a local phase…

Soft Condensed Matter · Physics 2022-12-07 Jeanne Decayeux , Marie Jardat , Pierre Illien , Vincent Dahirel

We address the gas, liquid, and crystal phase behaviour of active Brownian particles in three dimensions. The nonequilibrium force balance at coexistence leads to equality of state functions for which we use power functional approximations.…

Soft Condensed Matter · Physics 2024-02-28 Sophie Hermann , Matthias Schmidt

Living and engineered systems rely on the stable coexistence of two interspersed liquid phases. Yet surface tension drives their complete separation. Here we show that stable droplets of uniform and tuneable size can be produced through…

The purpose of this work is to use active particles to study the effect of facilitation on supercooled liquids. To this end we investigate the behavior of a model supercooled liquid doped with intermittently active and intermittently slowed…

Soft Condensed Matter · Physics 2023-08-11 Victor Teboul