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The proportional hazards model represents the most commonly assumed hazard structure when analysing time to event data using regression models. We study a general hazard structure which contains, as particular cases, proportional hazards,…

Methodology · Statistics 2018-05-24 Francisco J. Rubio , Laurent Remontet , Nicholas P. Jewell , Aurélien Belot

The proportional hazards (PH) and accelerated failure time (AFT) models are the most widely used hazard structures for analysing time-to-event data. When the goal is to identify variables associated with event times, variable selection is…

Methodology · Statistics 2026-02-04 Yulong Chen , Jim Griffin , Francisco Javier Rubio

This paper proposes a robust Bayesian accelerated failure time model for censored survival data. We develop a new family of life-time distributions using a scale mixture of the generalized gamma distributions, where we propose a novel super…

Methodology · Statistics 2025-04-16 Yasuyuki Hamura , Takahiro Onizuka , Shintaro Hashimoto , Shonosuke Sugasawa

The accelerated failure time (AFT) models have proved useful in many contexts, though heavy censoring (as for example in cancer survival) and high dimensionality (as for example in microarray data) cause difficulties for model fitting and…

Methodology · Statistics 2013-12-10 Md Hasinur Rahaman Khan , J. Ewart H. Shaw

We introduce a novel procedure to perform Bayesian non-parametric inference with right-censored data, the \emph{beta-Stacy bootstrap}. This approximates the posterior law of summaries of the survival distribution (e.g. the mean survival…

Methodology · Statistics 2021-11-17 Andrea Arfè , Pietro Muliere

Survival analysis is a challenging variation of regression modeling because of the presence of censoring, where the outcome measurement is only partially known, due to, for example, loss to follow up. Such problems come up frequently in…

Machine Learning · Computer Science 2022-06-28 Chirag Nagpal , Steve Yadlowsky , Negar Rostamzadeh , Katherine Heller

Under adaptive progressive Type-II censoring schemes, order restricted inference based on competing risks data is discussed in this article. The latent failure lifetimes for the competing causes are assumed to follow Weibull distributions,…

Methodology · Statistics 2022-05-10 Ayon Ganguly , Debanjan Mitra , Debasis Kundu

Modeling clustered/correlated failure time data has been becoming increasingly important in clinical trials and epidemiology studies. In this paper, we consider a semiparametric marginal promotion time cure model for clustered…

Methodology · Statistics 2025-05-15 Fei Xiao , Yingwei Peng , Dipankar Bandyopadhyayd , Yi Niu

Objective: To provide guidance for the use of the main functions available in R for performing post hoc Bayesian analysis of a randomized clinical trial with a survival endpoint using proportional hazard models. Study Design and Setting:…

Computation · Statistics 2019-09-10 Lucie Biard , Anne Bergeron , Sylvie Chevret

Restricted mean survival time (RMST) offers a compelling nonparametric alternative to hazard ratios for right-censored time-to-event data, particularly when the proportional hazards assumption is violated. By capturing the total event-free…

Methodology · Statistics 2025-01-28 Jinghao Sun , Douglas E. Schaubel , Eric J. Tchetgen Tchetgen

In this article, the weighted empirical likelihood is applied to a general setting of two-sample semiparametric models, which includes biased sampling models and case-control logistic regression models as special cases. For various types of…

Statistics Theory · Mathematics 2008-12-18 Jian-Jian Ren

Accurate predictions of when a component will fail are crucial when planning maintenance, and by modeling the distribution of these failure times, survival models have shown to be particularly useful in this context. The presented…

Machine Learning · Computer Science 2024-03-28 Olov Holmer , Mattias Krysander , Erik Frisk

This paper explores foundational and applied aspects of survival analysis, using fall risk assessment as a case study. It revisits key time-related probability distributions and statistical methods, including logistic regression, Poisson…

Machine Learning · Computer Science 2025-01-07 Tianhua Chen

We propose a generalized win fraction regression framework for prioritized composite survival outcomes. The framework models the conditional win fraction through a chosen link function (including identity, logit, or probit), thereby…

Methodology · Statistics 2026-04-08 Zhiqiang Cao , Xi Fang , Fan Li

A new method called SurvLIME for explaining machine learning survival models is proposed. It can be viewed as an extension or modification of the well-known method LIME. The main idea behind the proposed method is to apply the Cox…

Machine Learning · Computer Science 2020-03-19 Maxim S. Kovalev , Lev V. Utkin , Ernest M. Kasimov

The problem of how to best select variables for confounding adjustment forms one of the key challenges in the evaluation of exposure effects in observational studies, and has been the subject of vigorous recent activity in causal inference.…

Methodology · Statistics 2021-12-02 Kelly Van Lancker , Oliver Dukes , Stijn Vansteelandt

Models for predicting the risk of cardiovascular events based on individual patient characteristics are important tools for managing patient care. Most current and commonly used risk prediction models have been built from carefully selected…

This paper focuses on modelling surrender time for policyholders in the context of life insurance. In this setup, a large lapse rate at the first months of a contract is often observed, with a decrease in this rate after some months. The…

Applications · Statistics 2022-07-18 Viviana G. R. Lobo , Thais C. O. Fonseca , Mariane B. Alves

We consider a general proportional odds model for survival data under binary treatment, where the functional form of the covariates is left unspecified. We derive the efficient score for the conditional survival odds ratio given the…

Methodology · Statistics 2024-05-16 Denise Rava , Jelena Bradic , Ronghui Xu

We use statistical mechanics techniques, viz. the replica method, to model the effect of censoring on overfitting in Cox's proportional hazards model, the dominant regression method for time-to-event data. In the overfitting regime, Maximum…

Methodology · Statistics 2023-12-06 Emanuele Massa , Alexander Mozeika , Anthony Coolen
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