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Large language models (LLMs) are having transformative impacts across a wide range of scientific fields, particularly in the biomedical sciences. Just as the goal of Natural Language Processing is to understand sequences of words, a major…

Genomics · Quantitative Biology 2024-09-24 Gonzalo Benegas , Chengzhong Ye , Carlos Albors , Jianan Canal Li , Yun S. Song

SLiM is an efficient forward population genetic simulation designed for studying the effects of linkage and selection on a chromosome-wide scale. The program can incorporate complex scenarios of demography and population substructure,…

Populations and Evolution · Quantitative Biology 2013-01-15 Philipp W. Messer

Although Large Language Models (LLMs) have demonstrated remarkable code-generation ability, they still struggle with complex tasks. In real-world software development, humans usually tackle complex tasks through collaborative teamwork, a…

Software Engineering · Computer Science 2024-05-14 Yihong Dong , Xue Jiang , Zhi Jin , Ge Li

Advances in large language models (LLMs) have recently opened new and promising avenues for small-molecule drug discovery. Yet existing LLM-based approaches for molecular generation often suffer from high rates of invalid and low-quality…

Machine Learning · Computer Science 2026-05-15 Andrew Y. Zhou , Sharvaree Vadgama , Sumanth Varambally , Peter Eckmann , Michael K. Gilson , Rose Yu

Recent advances in Large Language Model (LLM) based Generative AI techniques have made it feasible to translate enterpriselevel code from legacy languages such as COBOL to modern languages such as Java or Python. While the results of…

Towards the vision of translating code that implements an algorithm from one programming language into another, this paper proposes an approach for automated program classification using bilateral tree-based convolutional neural networks…

Machine Learning · Computer Science 2017-12-01 Nghi D. Q. Bui , Lingxiao Jiang , Yijun Yu

The code written by developers usually suffers from efficiency problems and contain various performance bugs. These inefficiencies necessitate the research of automated refactoring methods for code optimization. Early research in code…

Software Engineering · Computer Science 2024-08-23 Shuzheng Gao , Cuiyun Gao , Wenchao Gu , Michael Lyu

High-throughput pheno-, geno-, and envirotyping allows characterization of plant genotypes and the trials they are evaluated in, producing different types of data. These different data modalities can be integrated into statistical or…

Large and small language models have been widely used for robotic task planning. At the same time, vision-language models (VLMs) have successfully tackled problems such as image captioning, scene understanding, and visual question…

Robotics · Computer Science 2026-03-09 Cristiano Battistini , Riccardo Andrea Izzo , Gianluca Bardaro , Matteo Matteucci

Constituency parsing is a fundamental yet unsolved challenge in natural language processing. In this paper, we examine the potential of recent large language models (LLMs) to address this challenge. We reformat constituency parsing as a…

Computation and Language · Computer Science 2025-09-29 Xuefeng Bai , Jialong Wu , Yulong Chen , Zhongqing Wang , Kehai Chen , Min Zhang , Yue Zhang

Models obtained by decision tree induction techniques excel in being interpretable.However, they can be prone to overfitting, which results in a low predictive performance. Ensemble techniques are able to achieve a higher accuracy. However,…

Machine Learning · Statistics 2016-11-18 Gilles Vandewiele , Olivier Janssens , Femke Ongenae , Filip De Turck , Sofie Van Hoecke

Educational interventions are effective tools for enhancing student learning. While Large Language Models (LLMs) allow for generating adaptive feedback at scale, current studies lack clear methodologies for providing Just-in-Time (JiT)…

Computation and Language · Computer Science 2026-05-27 Younghun Lee , Amir Bralin , Nobel Sanjay Rebello , Dan Goldwasser

Large Language Models (LLMs) have demonstrated great promise in generating code, especially when used inside an evolutionary computation framework to iteratively optimize the generated algorithms. However, in some cases they fail to…

Neural and Evolutionary Computing · Computer Science 2025-03-24 Niki van Stein , Anna V. Kononova , Lars Kotthoff , Thomas Bäck

In this paper, we propose a semiparametric, tree based joint latent class modeling approach (JLCT) to model the joint behavior of longitudinal and time-to-event data. Existing joint latent class modeling approaches are parametric and can…

Methodology · Statistics 2020-10-09 Ningshan Zhang , Jeffrey S. Simonoff

This paper presents the development of an AI-powered workflow that uses Large Language Models (LLMs) to assist in drafting schematic architectural floor plans from natural language prompts. The proposed system interprets textual input to…

Artificial Intelligence · Computer Science 2025-09-03 Jayakrishna Duggempudi , Lu Gao , Ahmed Senouci , Zhe Han , Yunpeng Zhang

The application of Genetic Programming to the discovery of empirical laws is often impaired by the huge size of the search space, and consequently by the computer resources needed. In many cases, the extreme demand for memory and CPU is due…

Artificial Intelligence · Computer Science 2016-08-16 Alain Ratle , Michèle Sebag

Reliability in cell type annotation is challenging in single-cell RNA-sequencing data analysis because both expert-driven and automated methods can be biased or constrained by their training data, especially for novel or rare cell types.…

Quantitative Methods · Quantitative Biology 2024-09-25 Wenjin Ye , Yuanchen Ma , Junkai Xiang , Hongjie Liang , Tao Wang , Qiuling Xiang , Andy Peng Xiang , Wu Song , Weiqiang Li , Weijun Huang

Large Language Models (LLMs) have demonstrated their remarkable capabilities in numerous fields. This survey focuses on how LLMs empower users, regardless of their technical background, to use human languages to automatically generate…

Software Engineering · Computer Science 2025-04-03 Nam Huynh , Beiyu Lin

Decision trees are a crucial class of models offering robust predictive performance and inherent interpretability across various domains, including healthcare, finance, and logistics. However, current tree induction methods often face…

Machine Learning · Computer Science 2025-03-19 Tennison Liu , Nicolas Huynh , Mihaela van der Schaar

As quantum computing advances, quantum programming libraries' heterogeneity and steady evolution create new challenges for software developers. Frequent updates in software libraries break working code that needs to be refactored, thus…

Software Engineering · Computer Science 2025-06-10 José Manuel Suárez , Luís Mariano Bibbó , Joaquín Bogado , Alejandro Fernandez