SLiM is an efficient forward population genetic simulation designed for studying the effects of linkage and selection on a chromosome-wide scale. The program can incorporate complex scenarios of demography and population substructure, various models for selection and dominance of new mutations, arbitrary gene and chromosomal structure, and user-defined recombination maps.
@article{arxiv.1301.3109,
title = {SLiM: Simulating Evolution with Selection and Linkage},
author = {Philipp W. Messer},
journal= {arXiv preprint arXiv:1301.3109},
year = {2013}
}
Comments
SLiM is a C++ command line program freely available under the GNU GPL license from http://www.stanford.edu/~messer/software. A comprehensive documentation for SLiM can be downloaded from the program website