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In clinical artificial intelligence (AI), graph representation learning, mainly through graph neural networks (GNNs), stands out for its capability to capture intricate relationships within structured clinical datasets. With diverse data --…

Machine Learning · Computer Science 2023-12-13 Ruth Johnson , Michelle M. Li , Ayush Noori , Owen Queen , Marinka Zitnik

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

Modeling disease progression through multiple stages is critical for clinical decision-making for chronic diseases, e.g., cancer, diabetes, chronic kidney diseases, and so on. Existing approaches often model the disease progression as a…

Machine Learning · Computer Science 2025-03-04 Haoyu Yang , Sanjoy Dey , Pablo Meyer

As the study of graph neural networks becomes more intensive and comprehensive, their robustness and security have received great research interest. The existing global attack methods treat all nodes in the graph as their attack targets.…

Machine Learning · Computer Science 2024-12-03 Guanghui Zhu , Mengyu Chen , Chunfeng Yuan , Yihua Huang

Semi-supervised domain adaptation leverages a few labeled and many unlabeled target samples, making it promising for addressing domain shifts in medical image analysis. However, existing methods struggle with severity classification due to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Shota Harada , Ryoma Bise , Kiyohito Tanaka , Seiichi Uchida

Importance: Lower-resource areas in Africa and Asia face a unique set of healthcare challenges: the dual high burden of communicable and non-communicable diseases; a paucity of highly trained primary healthcare providers in both rural and…

Contact tracing is an effective method to control emerging diseases. Since the 1980's, mathematical modelers are developing a consistent theory for contact tracing, with the aim to find effective and efficient implementations of contact…

Populations and Evolution · Quantitative Biology 2020-08-18 Johannes Müller , Mirjam Kretzschmar

Lifting uses a representative of indistinguishable individuals to exploit symmetries in probabilistic relational models, denoted as parametric factor graphs, to speed up inference while maintaining exact answers. In this paper, we show how…

Artificial Intelligence · Computer Science 2024-11-12 Malte Luttermann , Tanya Braun , Ralf Möller , Marcel Gehrke

We introduce the concept of pattern graphs--directed acyclic graphs representing how response patterns are associated. A pattern graph represents an identifying restriction that is nonparametrically identified/saturated and is often a…

Methodology · Statistics 2020-12-04 Yen-Chi Chen

We consider the problem of controlling a partially-observed dynamic process on a graph by a limited number of interventions. This problem naturally arises in contexts such as scheduling virus tests to curb an epidemic; targeted marketing in…

Machine Learning · Computer Science 2021-07-12 Eli A. Meirom , Haggai Maron , Shie Mannor , Gal Chechik

Heterogeneity is a hallmark of complex diseases. Regression-based heterogeneity analysis, which is directly concerned with outcome-feature relationships, has led to a deeper understanding of disease biology. Such an analysis identifies the…

Methodology · Statistics 2022-11-29 Ziye Luo , Xinyue Yao , Yifan Sun , Xinyan Fan

Graphical causal models are an important tool for knowledge discovery because they can represent both the causal relations between variables and the multivariate probability distributions over the data. Once learned, causal graphs can be…

Artificial Intelligence · Computer Science 2017-04-11 Andrew J Sedgewick , Joseph D. Ramsey , Peter Spirtes , Clark Glymour , Panayiotis V. Benos

The majority of data scientists and machine learning practitioners use relational data in their work [State of ML and Data Science 2017, Kaggle, Inc.]. But training machine learning models on data stored in relational databases requires…

Machine Learning · Computer Science 2020-02-07 Milan Cvitkovic

An important step for any causal inference study design is understanding the distribution of the treated and control subjects in terms of measured baseline covariates. However, not all baseline variation is equally important. In the…

Methodology · Statistics 2021-07-02 Rachael C. Aikens , Michael Baiocchi

We propose a method for tracking an unknown number of targets based on measurements provided by multiple sensors. Our method achieves low computational complexity and excellent scalability by running belief propagation on a suitably devised…

Data Structures and Algorithms · Computer Science 2017-05-24 Florian Meyer , Paolo Braca , Peter Willett , Franz Hlawatsch

A common goal in comparative effectiveness research is to estimate treatment effects on pre-specified subpopulations of patients. Though widely used in medical research, causal inference methods for such subgroup analysis remain…

Graph representation learning, a critical step in graph-centric tasks, has seen significant advancements. Earlier techniques often operate in an end-to-end setting, which heavily rely on the availability of ample labeled data. This…

Machine Learning · Computer Science 2024-09-23 Xingtong Yu , Yuan Fang , Zemin Liu , Yuxia Wu , Zhihao Wen , Jianyuan Bo , Xinming Zhang , Steven C. H. Hoi

Investigators are increasingly using novel methods for extending (generalizing or transporting) causal inferences from a trial to a target population. In many generalizability and transportability analyses, the trial and the observational…

Methodology · Statistics 2022-09-20 Yu-Han Chiu , Issa J. Dahabreh

Disease progression models are widely used to inform the diagnosis and treatment of many progressive diseases. However, a significant limitation of existing models is that they do not account for health disparities that can bias the…

Machine Learning · Computer Science 2025-05-01 Erica Chiang , Divya Shanmugam , Ashley N. Beecy , Gabriel Sayer , Deborah Estrin , Nikhil Garg , Emma Pierson

Graph sampling via crawling has become increasingly popular and important in the study of measuring various characteristics of large scale complex networks. While powerful, it is known to be challenging when the graph is loosely connected…

Social and Information Networks · Computer Science 2014-05-21 Junzhou Zhao , John C. S. Lui , Don Towsley , Pinghui Wang , Xiaohong Guan
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