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Additive manufacturing using light is commonly constrained by serial voxel-by-voxel or layer-by-layer processing, which fundamentally limits fabrication speed and scalability. Here, we introduce a single-exposure holographic…

Plastic scintillation detectors are increasingly used to measure dose distributions in the context of radiotherapy treatments. Their water-equivalence, real-time response and high spatial resolution distinguish them from traditional…

Medical Physics · Physics 2021-09-22 Emily Cloutier , Louis Archambault , Luc Beaulieu

Plastic scintillator detectors are used in high energy physics as well as for diagnostic imaging in medicine, beam monitoring on hadron therapy, muon tomography, dosimetry and many security applications. To combine particle tracking and…

A robust light storage and retrieval (LSR) in high dimensions is highly desirable for light and quantum information processing. However, most schemes on LSR realized up to now encounter problems due to not only dissipation, but also…

Optics · Physics 2016-04-19 Zhiming Chen , Zhengyang Bai , Hui-jun Li , Chao Hang , Guoxiang Huang

Laser Light Scattering (LLS) method, combined with a long-distance microscope was utilized to detect micrometer-sized particles on a smooth substrate. LLS was capable to detect individual particle release, shrink, or fragmentation during…

Plasma Physics · Physics 2023-07-13 D. Shefer , A. Nikipelov , M. van de Kerkhof , V. Banine , J. Beckers

Optogenetics has emerged as a powerful tool for disease modeling, enabling precise control of cellular activities through light stimulation and providing a valuable insights into disease mechanisms and therapeutic possibilities. Innovative…

We present a multimodal approach for measuring the three-dimensional (3D) refractive index (RI) and fluorescence distributions of live cells by combining optical diffraction tomography (ODT) and 3D structured illumination microscopy (SIM).…

Optics · Physics 2018-01-04 Seungwoo Shin , Doyeon Kim , Kyoohyun Kim , Yongkeun Park

We present OpenDosimeter (www.opendosimeter.org), an open hardware solution for real-time personal X-ray dose monitoring based on a scintillation counter. Using an X-ray sensor assembly (LYSO + SiPM) on a custom board powered by a Raspberry…

Optical diffraction tomography (ODT) is a three-dimensional (3D) quantitative phase imaging technique, which enables the reconstruction of the 3D refractive index (RI) distribution of a transparent sample. Due to its fast, non-invasive, and…

Optics · Physics 2018-11-14 Chansuk Park , Seungwoo Shin , Yongkeun Park

We have developed a novel in-vivo dosimeter based on glass encapsulated TLD rods. These encapsulated rods can be injected into mice and used for validating doses to an individual mouse in a protracted irradiation scenario where the mouse is…

Medical Physics · Physics 2019-09-18 Guy Garty , Monica C. Pujol , David J. Brenner

Hyperspectral 3D imaging captures both depth maps and hyperspectral images, enabling comprehensive geometric and material analysis. Recent methods achieve high spectral and depth accuracy; however, they require long acquisition times often…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Suhyun Shin , Seungwoo Yoon , Ryota Maeda , Seung-Hwan Baek

In this study we performed a feasibility investigation on implementing a fast and accurate dose calculation based on a deep learning technique. A two dimensional (2D) fluence map was first converted into a three dimensional (3D) volume…

Medical Physics · Physics 2021-02-03 Jiawei Fan , Lei Xing , Peng Dong , Jiazhou Wang , Weigang Hu , Yong Yang

We describe a novel technique to characterize ultrashort electron bunches in X-ray Free-Electron Lasers. Namely, we propose to use coherent Optical Transition Radiation to measure three-dimensional (3D) electron density distributions. Our…

This study introduces the HYPERSCINT research platform, the first commercially available scintillation dosimetry platform capable of multi-point dosimetry through the hyperspectral approach. Optic and dosimetric performances of the system…

Instrumentation and Detectors · Physics 2021-04-19 Emilie Jean , Francois Therriault-Proulx , Luc Beaulieu

Tomography aims to recover a three-dimensional (3D) density map of a medium or an object. In medical imaging, it is extensively used for diagnostics via X-ray computed tomography (CT). Optical diffusion tomography is an alternative to X-ray…

Computational Physics · Physics 2020-05-26 Aviad Levis , Yoav Y. Schechner , Anthony B. Davis , Jesse Loveridge

Spatial light modulators (SLMs) are devices for modulating amplitude, phase or polarization of a light beam on demand. Such devices have been playing an indispensable inuence in many areas from our daily entertainments to scientific…

Optics · Physics 2020-03-12 Shengchao Gong , Mengxin Ren , Wei Wu , Wei Cai , Jingjun Xu

The measurement of three-dimensional (3D) images and the analysis of subcellular organelles are crucial for the study of the pathophysiology of cells and tissues. Optical diffraction tomography (ODT) facilitates label-free and quantitative…

Image and Video Processing · Electrical Eng. & Systems 2019-10-08 Taean Chang , Seungwoo Shin , Moosung Lee , YongKeun Park

FLASH-RT has proven beneficial in preclinical studies. However, the lack of accurate real time 2D dosimetry is a limiting factor. In this work, an innovative solution for 2D real time dosimetry in UHDR electron beams is presented. The…

In these days, 3D-printer is on the rise in various fields including radiation therapy. This preliminary study aimed to estimate the dose characteristics of the 3D-printer materials which could be used as the compensator or immobilizer in…

Medical Physics · Physics 2015-03-11 Seonghoon Jeong , Myonggeun yoon , Weon Kuu Chung , Dong Wook Kim

Stereotactic body radiation therapy allows for a precise and accurate dose delivery. Organ motion during treatment bears the risk of undetected high dose healthy tissue exposure. An organ very susceptible to high dose is the oesophagus. Its…

Medical Physics · Physics 2021-06-22 Tobias Fechter , Sonja Adebahr , Anca-Ligia Grosu , Dimos Baltas