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Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

A recent interest in resting state functional magnetic resonance imaging (rsfMRI) lies in subdividing the human brain into anatomically and functionally distinct regions of interest. For example, brain parcellation is often used for…

A novel approach rooted on the notion of consensus clustering, a strategy developed for community detection in complex networks, is proposed to cope with the heterogeneity that characterizes connectivity matrices in health and disease. The…

Neurons and Cognition · Quantitative Biology 2017-05-09 Javier Rasero , Mario Pellicoro , Leonardo Angelini , Jesus M. Cortes , Daniele Marinazzo , Sebastiano Stramaglia

Functional connectivity (FC) derived from functional magnetic resonance imaging (fMRI) data offers vital insights for understanding brain function and neurological and psychiatric disorders. Unsupervised clustering methods are desired to…

Methodology · Statistics 2025-12-04 Yixi Xu , Yi Zhao

In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores.…

Methodology · Statistics 2022-12-06 Arkaprava Roy

Cytoarchitectonic parcellations of the human brain serve as anatomical references in multimodal atlas frameworks. They are based on analysis of cell-body stained histological sections and the identification of borders between brain areas.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Hannah Spitzer , Kai Kiwitz , Katrin Amunts , Stefan Harmeling , Timo Dickscheid

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Recent advancements in understanding the brain's functional organization related to behavior have been pivotal, particularly in the development of predictive models based on brain connectivity. Traditional methods in this domain often…

Applications · Statistics 2024-08-01 Wanwan Xu , Selena Wang , Chichun Tan , Xilin Shen , Wenjing Luo , Todd Constable , Tianxi Li , Yize Zhao

Brain atlases are a ubiquitous tool used for analyzing and interpreting brain imaging datasets. Traditionally, brain atlases divided the brain into regions separated by anatomical landmarks. In the last decade, several attempts have been…

Quantitative Methods · Quantitative Biology 2018-02-08 Pantea Moghimi , Kelvin O. Lim , Theoden I. Netoff

Whole-brain tractography in diffusion MRI is often followed by a parcellation in which each streamline is classified as belonging to a specific white matter bundle, or discarded as a false positive. Efficient parcellation is important both…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Valentin von Bornhaupt , Johannes Grün , and Justus Bisten , Tobias Bauer , Theodor Rüber , Thomas Schultz

The human structural connectome has a complex internal community organization, characterized by a high degree of overlap and related to functional and cognitive phenomena. We explored connectivity properties in connectome networks and…

Disordered Systems and Neural Networks · Physics 2025-02-24 V. Tiselko , O. Dogonasheva , A. Myshkin , O. Valba

We propose a method that combines signals from many brain regions observed in functional Magnetic Resonance Imaging (fMRI) to predict the subject's behavior during a scanning session. Such predictions suffer from the huge number of brain…

Computer Vision and Pattern Recognition · Computer Science 2011-04-29 Vincent Michel , Alexandre Gramfort , Gaël Varoquaux , Evelyn Eger , Christine Keribin , Bertrand Thirion

Representation of brain network interactions is fundamental to the translation of neural structure to brain function. As such, methodologies for mapping neural interactions into structural models, i.e., inference of functional connectome…

Neurons and Cognition · Quantitative Biology 2022-03-18 Rahul Biswas , Eli Shlizerman

Advanced brain imaging techniques make it possible to measure individuals' structural connectomes in large cohort studies non-invasively. The structural connectome is initially shaped by genetics and subsequently refined by the environment.…

Applications · Statistics 2018-06-11 Zhengwu Zhang , Genevera I. Allen , Hongtu Zhu , David Dunson

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections at macro scale. Over the last two decades, the study of brain connectivity using…

Quantitative Methods · Quantitative Biology 2021-04-26 Fan Zhang , Alessandro Daducci , Yong He , Simona Schiavi , Caio Seguin , Robert Smith , Chun-Hung Yeh , Tengda Zhao , Lauren J. O'Donnell

Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…

Neurons and Cognition · Quantitative Biology 2025-07-09 Sam Frank Kelemen , Joaquín Gõni , Sérgio Pequito , Arian Ashourvan

Estimating causal interactions in the brain from functional magnetic resonance imaging (fMRI) data remains a challenging task. Multiple studies have demonstrated that all current approaches to determine direction of connectivity perform…

Neurons and Cognition · Quantitative Biology 2019-05-31 Natalia Bielczyk , Alberto Llera , Jan Buitelaar , Jeffrey Glennon , Christian Beckmann

Mapping the functional connectome has the potential to uncover key insights into brain organisation. However, existing workflows for functional connectomics are limited in their adaptability to new data, and principled workflow design is a…

Neurons and Cognition · Quantitative Biology 2022-06-02 Rastko Ciric , Armin W. Thomas , Oscar Esteban , Russell A. Poldrack

A central question in neuroscience is how self-organizing dynamic interactions in the brain emerge on their relatively static structural backbone. Due to the complexity of spatial and temporal dependencies between different brain areas,…

Neurons and Cognition · Quantitative Biology 2020-10-15 Simon Wein , Wilhelm Malloni , Ana Maria Tomé , Sebastian M. Frank , Gina-Isabelle Henze , Stefan Wüst , Mark W. Greenlee , Elmar W. Lang