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Complex network analysis has an increasing relevance in the study of neurological disorders, enhancing the knowledge of brain's structural and functional organization. Network structure and efficiency reveal different brain states along…

Neurons and Cognition · Quantitative Biology 2022-01-24 Nicolás J. Gallego-Molina , Andrés Ortiz , Francisco J. Martínez-Murcia , Marco Formoso , Almudena Giménez

Recent neuroimaging studies have shown that functional connectomes are unique to individuals, i.e., two distinct fMRIs taken over different sessions of the same subject are more similar in terms of their connectomes than those from two…

Computer Vision and Pattern Recognition · Computer Science 2019-08-12 Vikram Ravindra , Petros Drineas , Ananth Grama

The representation of the flow of information between neurons in the brain based on their activity is termed the causal functional connectome. Such representation incorporates the dynamic nature of neuronal activity and causal interactions…

Neurons and Cognition · Quantitative Biology 2022-11-16 Rahul Biswas , Eli Shlizerman

The behavior of many complex systems is determined by a core of densely interconnected units. While many methods are available to identify the core of a network when connections between nodes are all of the same type, a principled approach…

Neurons and Cognition · Quantitative Biology 2018-09-14 Federico Battiston , Jeremy Guillon , Mario Chavez , Vito Latora , Fabrizio De Vico Fallani

Motivated by modern observational studies, we introduce a class of functional models that expands nested and crossed designs. These models account for the natural inheritance of correlation structure from sampling design in studies where…

Applications · Statistics 2013-04-26 Haochang Shou , Vadim Zipunnikov , Ciprian M. Crainiceanu , Sonja Greven

In signal processing, exploring complex systems through network representations has become an area of growing interest. This study introduces the modularity graph, a new graph-based feature, to highlight the relationship across the graph…

Neurons and Cognition · Quantitative Biology 2024-10-23 Tiziana Cattai , Camilla Caporali , Marie-Constance Corsi , Stefania Colonnese

A key question in modern neuroscience is how cognitive changes in a human brain can be quantified and captured by functional connectomes (FC) . A systematic approach to measure pairwise functional distance at different brain states is…

Neurons and Cognition · Quantitative Biology 2018-09-26 Enrico Amico , Alex Arenas , Joaquin Goni

White Matter Tract Segmentation is imperative for studying brain structural connectivity, neurological disorders and neurosurgery. This task remains complex, as tracts differ among themselves, across subjects and conditions, yet have…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Anoushkrit Goel , Simroop Singh , Ankita Joshi , Ranjeet Ranjan Jha , Chirag Ahuja , Aditya Nigam , Arnav Bhavsar

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

Applications · Statistics 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

A novel non-parametric estimator of the correlation between grouped measurements of a quantity is proposed in the presence of noise. This work is primarily motivated by functional brain network construction from fMRI data, where brain…

Methodology · Statistics 2023-02-16 Hanâ Lbath , Alexander Petersen , Wendy Meiring , Sophie Achard

Recent progress in diffusion MRI and tractography algorithms as well as the launch of the Human Connectome Project (HCP) have provided brain research with an abundance of structural connectivity data. In this work, we describe and evaluate…

Neurons and Cognition · Quantitative Biology 2016-06-02 Kamal Shadi , Saideh Bakhshi , David A. Gutman , Helen S. Mayberg , Constantine Dovrolis

Generalized linear and additive models are very efficient regression tools but the selection of relevant terms becomes difficult if higher order interactions are needed. In contrast, tree-based methods also known as recursive partitioning…

Methodology · Statistics 2015-04-21 Gerhard Tutz , Moritz Berger

A major archetype of artificial intelligence is developing algorithms facilitating temporal efficiency and accuracy while boosting the generalization performance. Even with the latest developments in machine learning, a key limitation has…

Machine Learning · Computer Science 2022-01-31 Meric Yucel , Serdar Bagis , Ahmet Sertbas , Mehmet Sarikaya , Burak Berk Ustundag

The brain is often studied from a network perspective, where functional activity is assessed using functional Magnetic Resonance Imaging (fMRI) to estimate connectivity between predefined neuronal regions. Functional connectivity can be…

Applications · Statistics 2025-07-22 Olivier Bisson , Yanis Aeschlimann , Samuel Deslauriers-Gauthier , Xavier Pennec

Mapping the connectivity of neurons in the brain (i.e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them. Because of this,…

Neurons and Cognition · Quantitative Biology 2014-09-08 Ting Zhao , Stephen M Plaza

Human brain structural networks contain sets of centrally embedded hub regions that enable efficient information communication. However, it remains largely unknown about categories of structural brain hubs and their microstructural,…

Neurons and Cognition · Quantitative Biology 2016-09-13 Xindi Wang , Qixiang Lin , Mingrui Xia , Yong He

The analysis of complex networks has revealed patterns of organization in a variety of natural and artificial systems, including neuronal networks of the brain at multiple scales. In this paper, we describe a novel analysis of the…

Neurons and Cognition · Quantitative Biology 2015-06-26 Luciano da F. Costa , Olaf Sporns

We propose a flexible and multi-scale method for organizing, visualizing, and understanding datasets sampled from or near stratified spaces. The first part of the algorithm produces a cover tree using adaptive thresholds based on a…

Computational Geometry · Computer Science 2016-03-01 Paul Bendich , Ellen Gasparovic , Christopher J. Tralie , John Harer

Connectivity information derived from diffusion-weighted magnetic resonance images~(DW-MRIs) plays an important role in studying human subcortical gray matter structures. However, due to the $O(N^2)$ complexity of computing the connectivity…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Zhangxing Bian , Muhan Shao , Jiachen Zhuo , Rao P. Gullapalli , Aaron Carass , Jerry L. Prince

P300 is an Event-Related Potential widely used in Brain-Computer Interfaces, but its detection is challenging due to inter-subject and temporal variability. This work introduces a clustering methodology based on Normalized Compression…

Machine Learning · Computer Science 2025-02-04 Guillermo Sarasa , Ana Granados , Francisco B Rodríguez
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