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Computational phylogenetics has become an established tool in historical linguistics, with many language families now analyzed using likelihood-based inference. However, standard approaches rely on expert-annotated cognate sets, which are…

Computation and Language · Computer Science 2026-03-30 Gerhard Jäger

The metric space of phylogenetic trees defined by Billera, Holmes, and Vogtmann, which we refer to as BHV space, provides a natural geometric setting for describing collections of trees on the same set of taxa. However, it is sometimes…

Populations and Evolution · Quantitative Biology 2018-07-12 Gillian Grindstaff , Megan Owen

High-throughput sequencing (HTS) is revolutionizing biological research by enabling scientists to quickly and cheaply query variation at a genomic scale. Despite the increasing ease of obtaining such data, using these data effectively still…

Genomics · Quantitative Biology 2012-11-09 Sonal Singhal

When conducting inter-species regression analyses, the phylogenetic relationships between the individual species need to be taken into account. In this paper, a procedure for conducting such analyses is proposed, which only requires the use…

Populations and Evolution · Quantitative Biology 2007-05-23 Brigitte Pallmann , A. D. Barbour , D. J. Hosken , P. I. Ward

Reconciling a gene tree with a species tree is an important task that reveals much about the evolution of genes, genomes, and species, as well as about the molecular function of genes. A wide array of computational tools have been devised…

Populations and Evolution · Quantitative Biology 2012-12-11 Yun Yu , Luay Nakhleh

In biology, a phylogenetic tree is a tool to represent the evolutionary relationship between species. Unfortunately, the classical Schr\"oder tree model is not adapted to take into account the chronology between the branching nodes. In…

Data Structures and Algorithms · Computer Science 2019-01-15 Olivier Bodini , Antoine Genitrini , Mehdi Naima

This paper introduces PhyloLM, a method adapting phylogenetic algorithms to Large Language Models (LLMs) to explore whether and how they relate to each other and to predict their performance characteristics. Our method calculates a…

Computation and Language · Computer Science 2025-12-09 Nicolas Yax , Pierre-Yves Oudeyer , Stefano Palminteri

Gene gains and losses have shaped the gene repertoire of species since the universal last common ancestor to species today. Genes in extant species were gained at different historical times via de novo creation of new genes, duplication of…

Populations and Evolution · Quantitative Biology 2018-02-19 Haiming Tang , Paul Thomas , Haoran Xia

The aim of this review is to present and analyze the probabilistic models of mathematical phylogenetics which have been intensively used in recent years in biology as the cornerstone of attempts to infer and reconstruct the ancestral…

Populations and Evolution · Quantitative Biology 2020-01-08 Peter D Jarvis , Jeremy G Sumner

Evolutionary relationships between species are usually represented in phylogenies, i.e. evolutionary trees, which are a type of networks. The terminal nodes of these trees represent species, which are made of individuals and populations…

Populations and Evolution · Quantitative Biology 2007-07-11 E. Hernandez-Garcia , E. A. Herrada , A. F. Rozenfeld , C. J. Tessone , V. M. Eguiluz , C. M. Duarte , S. Arnaud-Haond , E. Serrao

This article shows how to fit reticulate finite and infinite sites sequence spectra to aligned data from five modern human genomes (San, Yoruba, French, Han and Papuan) plus two archaic humans (Denisovan and Neanderthal), to better infer…

Populations and Evolution · Quantitative Biology 2011-12-30 Peter J. Waddell , Jorge Ramos , Xi Tan

While linear mixed model (LMM) has shown a competitive performance in correcting spurious associations raised by population stratification, family structures, and cryptic relatedness, more challenges are still to be addressed regarding the…

Machine Learning · Computer Science 2023-02-15 Wenting Ye , Xiang Liu , Tianwei Yue , Wenping Wang

Exploring the genetic basis of heritable traits remains one of the central challenges in biomedical research. In simple cases, single polymorphic loci explain a significant fraction of the phenotype variability. However, many traits of…

Populations and Evolution · Quantitative Biology 2015-03-20 Barbara Rakitsch , Christoph Lippert , Oliver Stegle , Karsten Borgwardt

Genomes and genes diversify during evolution; however, it is unclear to what extent genes still retain the relationship among species. Model species for molecular phylogenetic studies include yeasts and viruses whose genomes were sequenced…

Genomics · Quantitative Biology 2008-06-09 Yunfeng Shan , Xiu-Qing Li

Species' interactions are shaped by their traits. Thus, we expect traits -- in particular, trait (dis)similarity -- to play a central role in determining whether a particular set of species coexists. Traits are, in turn, the outcome of an…

Populations and Evolution · Quantitative Biology 2025-03-19 Carlos A. Servan , Jose A. Capitan , Zachary R. Miller , Stefano Allesina

Phylogenetic trees elucidate evolutionary relationships among species, but phylogenetic inference remains challenging due to the complexity of combining continuous (branch lengths) and discrete parameters (tree topology). Traditional Markov…

Populations and Evolution · Quantitative Biology 2024-12-30 ChenRui Duan , Zelin Zang , Siyuan Li , Yongjie Xu , Stan Z. Li

The evaluation of large language models faces significant challenges. Technical benchmarks often lack real-world relevance, while existing human preference evaluations suffer from unrepresentative sampling, superficial assessment depth, and…

Computation and Language · Computer Science 2026-03-06 Nora Petrova , Andrew Gordon , Enzo Blindow

Recent studies have shown that hybridization between modern and archaic humans was commonplace in the history of our species. After admixture, some individuals with admixed autosomes carried the modern Homo Sapiens uniparental DNAs, while…

Other Quantitative Biology · Quantitative Biology 2020-03-31 Hongyao Chen , Shi Huang

Identifying undocumented or potential future interactions among species is a challenge facing modern ecologists. Recent link prediction methods rely on trait data, however large species interaction databases are typically sparse and…

Applications · Statistics 2019-09-23 Mohamad Elmasri , Maxwell J. Farrell , T. Jonathan Davies , David A. Stephens

Compatibility of phylogenetic trees is the most important concept underlying widely-used methods for assessing the agreement of different phylogenetic trees with overlapping taxa and combining them into common supertrees to reveal the tree…

Discrete Mathematics · Computer Science 2011-11-09 Merce Llabres , Jairo Rocha , Francesc Rossello , Gabriel Valiente
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