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This article shows how 3D geometric morphometric data can be analyzed using newly developed distance-based evolutionary tree inference methods, with extensions to planar graphs. Application of these methods to 3D representations of the…

Populations and Evolution · Quantitative Biology 2015-01-05 Peter J. Waddell

Divergence time estimation requires the reconciliation of two major sources of data. These are fossil and/or biogeographic evidence that give estimates of the absolute age of nodes (ancestors) and molecular estimates that give us estimates…

Populations and Evolution · Quantitative Biology 2008-12-31 Peter J Waddell

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

Populations and Evolution · Quantitative Biology 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

A range of a priori hypotheses about the evolution of modern and archaic genomes are further evaluated and tested. In addition to the well-known splits/introgressions involving Neanderthal genes into out-of- Africa people, or Denisovan…

Populations and Evolution · Quantitative Biology 2013-12-31 Peter J. Waddell

Phylogenetic reconstruction aims at finding plausible hypotheses of the evolutionary history of genes or species based on genomic sequence information. The distinction of orthologous genes (genes that having a common ancestry and diverged…

Populations and Evolution · Quantitative Biology 2016-02-29 Marc Hellmuth , Nicolas Wieseke

Most genes are part of larger families of evolutionary related genes. The history of gene families typically involves duplications and losses of genes as well as horizontal transfers into other organisms. The reconstruction of detailed gene…

Populations and Evolution · Quantitative Biology 2023-04-25 Marc Hellmuth , Peter F. Stadler

With advances in sequencing technologies, there are now massive amounts of genomic data from across all life, leading to the possibility that a robust Tree of Life can be constructed. However, "gene tree heterogeneity", which is when…

Populations and Evolution · Quantitative Biology 2018-03-08 Sebastien Roch , Michael Nute , Tandy Warnow

Phylogenomics heavily relies on well-curated sequence data sets that consist, for each gene, exclusively of 1:1-orthologous. Paralogs are treated as a dangerous nuisance that has to be detected and removed. We show here that this severe…

Discrete Mathematics · Computer Science 2017-12-19 Marc Hellmuth , Nicolas Wieseke , Marcus Lechner , Hans-Peter Lenhof , Martin Middendorf , Peter F. Stadler

We consider a large population of asexually reproducing individuals in absence of selective pressure. The population size is maintained constant by the environment. We find out that distances between individuals (time from the last common…

Statistical Mechanics · Physics 2007-05-23 Maurizio Serva

Phylogeny can be inferred using two sources of data from an organism: morphological data and molecular data. Historically, phylogenies were usually inferred using morphological characters, but some morphological features may not necessarily…

Populations and Evolution · Quantitative Biology 2023-12-19 Ray Han

Phylogenetic comparative methods are well established tools for using inter-species variation to analyse phenotypic evolution and adaptation. They are generally hampered, however, by predominantly univariate approaches and failure to…

Populations and Evolution · Quantitative Biology 2024-12-13 Krzysztof Bartoszek

Genetic association data from national biobanks and large-scale association studies have provided new prospects for understanding the genetic evolution of complex traits and diseases in humans. In turn, genomes from ancient human…

Populations and Evolution · Quantitative Biology 2021-08-06 Evan K. Irving-Pease , Rasa Muktupavela , Michael Dannemann , Fernando Racimo

Understanding which phenotypic traits are consistently correlated throughout evolution is a highly pertinent problem in modern evolutionary biology. Here, we propose a multivariate phylogenetic latent liability model for assessing the…

Populations and Evolution · Quantitative Biology 2015-09-17 Gabriela B. Cybis , Janet S. Sinsheimer , Trevor Bedford , Alison E. Mather , Philippe Lemey , Marc A. Suchard

Phylogenetic analyses of gene expression have great potential for addressing a wide range of questions. These analyses will, for example, identify genes that have evolutionary shifts in expression that are correlated with evolutionary…

Populations and Evolution · Quantitative Biology 2014-01-14 Casey W. Dunn , Xi Luo , Zhijin Wu

Phylogenetic methods typically rely on an appropriate model of how data evolved in order to infer an accurate phylogenetic tree. For molecular data, standard statistical methods have provided an effective strategy for extracting…

Populations and Evolution · Quantitative Biology 2015-01-21 Robert W. Scotland , Mike Steel

Phylogenetic trees describe the evolutionary history of a group of present-day species from a common ancestor. These trees are typically reconstructed from aligned DNA sequence data. In this paper we analytically address the following…

Populations and Evolution · Quantitative Biology 2008-07-14 Mike Steel , Laszlo Szekely , Elchanan Mossel

We consider the following question: how close to the ancestral root of a phylogenetic tree is the most recent common ancestor of $k$ species randomly sampled from the tips of the tree? For trees having shapes predicted by the Yule-Harding…

Populations and Evolution · Quantitative Biology 2025-12-03 Michael Fuchs , Mike Steel

Species tree estimation is a complex problem, due to the fact that different parts of the genome can have different evolutionary histories than the genome itself. One of the causes for this discord is incomplete lineage sorting (also called…

Populations and Evolution · Quantitative Biology 2019-04-09 Erin Molloy , Tandy Warnow

Phylogeny is the study of the relations between biological entities. From it, the need to compare tree-like graphs has risen and several metrics were established and researched, but since there is no definitive way to compare them, its…

Data Structures and Algorithms · Computer Science 2018-04-12 Bernardo Lopo Tavares

Phylogenetic mixture models are statistical models of character evolution allowing for heterogeneity. Each of the classes in some unknown partition of the characters may evolve by different processes, or even along different trees. The…

Populations and Evolution · Quantitative Biology 2010-11-19 John A. Rhodes , Seth Sullivant
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