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The evaluation of obstructions (stenosis) in coronary arteries is currently done by a physician's visual assessment of coronary angiography video sequences. It is laborious, and can be susceptible to interobserver variation. Prior studies…
Glaucoma is the leading cause of irreversible but preventable blindness in the world. Its major treatable risk factor is the intra-ocular pressure, although other biomarkers are being explored to improve the understanding of the…
Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…
In this work, we investigate how concepts from medical flow visualization can be applied to enhance stroke prevention diagnostics. Our focus lies on carotid stenoses, i.e., local narrowings of the major brain-supplying arteries, which are a…
The liver has a unique blood supply system and plays an important role in the human blood circulatory system. Thus, hemodynamic problems related to the liver serve as an important part in clinical diagnosis and treatment. Although…
Aortic stenosis (AS) is the most common valvular heart disease in developed countries. High-fidelity preclinical models can improve AS management by enabling therapeutic innovation, early diagnosis, and tailored treatment planning. However,…
Physical systems with complex unsteady dynamics, such as fluid flows, are often poorly represented by a single mean solution. For many practical applications, it is crucial to access the full distribution of possible states, from which…
A method is presented for the registration of MRA and 4D Flow images, with the goal of calculating blood flow properties using both modalities simultaneously. In particular, the method produces an alignment of segmentations of vessel…
Computational fluid dynamics (CFD) studies have been increasingly used for blood flow simulations in intracranial aneurysms (ICAs). However, despite the continuous progress of body-fitted CFD solvers, generating a high quality mesh is still…
We present a fully automatic, graph-based technique for extracting the retinal vascular topology -- that is, how different vessels are connected to each other -- given a single color fundus image. Determining this connectivity is very…
Neural networks have been applied to tackle many-body electron correlations for small molecules and physical models in recent years. Here we propose a new architecture that extends molecular neural networks with the inclusion of periodic…
Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by rapid and irregular contractions of the atria. It significantly elevates the risk of strokes due to slowed blood flow in the atria, especially in the left atrial…
Personalised 3D vascular models are valuable for diagnosis, prognosis and treatment planning in patients with cardiovascular disease. Traditionally, such models have been constructed with explicit representations such as meshes and voxel…
Zero-dimensional (0D) cardiovascular models are reduced-order models used to study global circulation dynamics and transport. They provide estimates of biomarkers (such as pressure, flow rates, and concentrations) for surgery planning and…
Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…
Purpose: Radio-frequency ablations play an important role in the therapy of malignant liver lesions. The navigation of a needle to the lesion poses a challenge for both the trainees and intervening physicians. Methods: This publication…
We use a one dimensional symmetric exclusion model to study pressure and osmosis driven flows through molecular-sized channels, such as biological membrane channels and zeolite pores. Analytic expressions are found for the steady-state flow…
We derive a full 3-dimensional (3-D) model of inhomogeneous -- anisotropic diffusion in a tumor region coupled to a binary population model. The diffusion tensors are acquired using Diffusion Tensor Magnetic Resonance Imaging (DTI) from a…
The examination of Osteoarthritis disease through X-ray by rheumatology can be classified into four grade of severity. This paper discusses about the application of artificial neural network backpropagation method for measuring the severity…
The automatic segmentation of blood vessels in fundus images can help analyze the condition of retinal vasculature, which is crucial for identifying various systemic diseases like hypertension, diabetes, etc. Despite the success of Deep…