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A new variant of the pencil-beam (PB) algorithm for dose distribution calculation for radiotherapy with protons and heavier ions, the grid-dose spreading (GDS) algorithm, is proposed. The GDS algorithm is intrinsically faster than…

Medical Physics · Physics 2011-11-10 Nobuyuki Kanematsu , Shunsuke Yonai , Azusa Ishizaki

Currently existing energy-stable parametric finite element methods for surface diffusion flow and other flows are usually limited to first-order accuracy in time. Designing a high-order algorithm for geometric flows that can also be…

Numerical Analysis · Mathematics 2024-07-15 Meng Li , Yihang Guo , Jingjiang Bi

A Geant4 based simulation platform of the Holland Proton Therapy Centre (HollandPTC, Netherlands) R&D beamline (G4HPTC-R&D) was developed to enable the planning, optimisation and advanced dosimetry for radiobiological studies. It…

Medical Physics · Physics 2023-06-01 C. F. Groenendijk , M. Rovituso , D. Lathouwers , J. M. C. Brown

We revisit the method of cumulants for analysing dynamic light scattering data in particle sizing applications. Here the data, in the form of the time correlation function of scattered light, is written as a series involving the first few…

Soft Condensed Matter · Physics 2015-04-27 Alastair G. Mailer , Paul S. Clegg , Peter N. Pusey

Proton radiography is used in various high-energy-density (HED) plasma experiments. In this paper, we describe a Monte Carlo and ray-tracing simulation tool called MPRAD that can be used for modeling the deflection of proton beams in…

Plasma Physics · Physics 2020-01-08 Yingchao Lu , Hui Li , Kirk A. Flippo , Kwyntero Kelso , Andy Liao , Shengtai Li , Edison Liang

Diffusing alpha-emitters radiation therapy (Alpha-DaRT) is a new modality that uses alpha particles to treat solid tumors. Alpha-DaRT employs interstitial sources loaded with low activities of Radium-224, which release a chain of…

We report a detailed and systematic study of wave propagation through a stochastic absorbing random medium. Stochastic absorption is modeled by introducing an attenuation constant per unit length $\alpha$ in the free propagation region of…

Disordered Systems and Neural Networks · Physics 2009-10-31 Sandeep K. Joshi , Debendranath Sahoo , A. M. Jayannavar

We present computer simulations about the spatial and temporal evolution of a 1-MeV proton microbeam transmitted through an insulating macrocapillary with the length of 45 mm and with the inner diameter of 800 {\mu}m. The axis of the…

Atomic Physics · Physics 2021-04-26 G. U. L. Nagy , Z. T. Gaál , I. Rajta , K. Tőkési

Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…

Medical Physics · Physics 2023-04-13 Sylvain Deffet , Edmond Sterpin

We develop a stable and efficient numerical scheme for modeling the optical field evolution in a nonlinear dispersive cavity with counter propagating waves and complex, semiconductor physics gain dynamics that are expensive to evaluate. Our…

For atoms embedded in dense plasma, the plasma screening effects will greatly alter their structure and dynamics, and then determine the radiation transport properties of the plasma. In the present work, a new statistical model is proposed…

Plasma Physics · Physics 2020-11-25 Fuyang Zhou , Yizhi Qu , Junwen Gao , Yulong Ma , Yong Wu , Jianguo Wang

A broad-beam-delivery system for heavy-charged-particle radiotherapy often employs multiple collimators and a range-compensating filter, which potentially offer complex beam customization. In treatment planning, it is however difficult for…

Medical Physics · Physics 2012-01-11 Nobuyuki Kanematsu

Electron beam probe (EBP) is a new principle detector, which makes use of a low-intensity and low-energy electron beam to measure the transverse profile, bunch shape, beam neutralization and beam wake field of an intense beam with small…

Accurately quantifying the energy loss rate of proton beams in liquid water is crucial for the precise application and improvement of proton therapy, whereas the slowing down of proton in water ices also plays an important role in…

HollandPTC is an independent outpatient center for proton therapy, scientific research, and education. Patients with different types of cancer are treated with Intensity Modulated Proton Therapy (IMPT). In addition, the HollandPTC R&D…

The paper provides a novel framework to study the accuracy and stability of numerical integration schemes when employed for the time domain simulation of power systems. A matrix pencil-based approach is adopted to evaluate the error between…

Systems and Control · Electrical Eng. & Systems 2022-01-25 Georgios Tzounas , Ioannis Dassios , Federico Milano

A statistical algorithm for estimating the characteristic parameter $\alpha$ of the stable law is presented and the estimate of its quadratic deviation is obtained in the paper. This algorithm is applied in the description of the…

Statistics Theory · Mathematics 2020-04-03 Olga Yanushkevichiene , Viacheslav Saenko

Stable distributions are an important class of infinitely-divisible probability distributions, of which two special cases are the Cauchy distribution and the normal distribution. Aside from a few special cases, the density function for…

Numerical Analysis · Mathematics 2021-08-31 Sebastian Ament , Michael O'Neil

We study the optimal focusing of two-level atoms with a near resonant standing wave light, using both classical and quantum treatments of the problem. Operation of the focusing setup is considered as a nonlinear spatial squeezing of atoms…

Quantum Physics · Physics 2015-07-15 R. Arun , Offir Cohen , I. Sh. Averbukh

Diffusion models achieve state-of-the-art image generation but remain computationally costly due to iterative denoising. Latent-space models like Stable Diffusion reduce overhead yet lose fine detail, while retrieval-augmented methods…

Machine Learning · Computer Science 2025-12-23 Bilal Faye , Hanane Azzag , Mustapha Lebbah